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  1. 5421
    “…Animals were analyzed at two different ages: i) 13-weeks old young mice, and ii) 12-months old middle-aged mice. In addition, the effects of 10 weeks-long high-fat diet (HFD) were investigated in middle-aged mice. …”
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    IGF1R is a mediator of sex-specific metabolism in mice: Effects of age and high-fat diet
  2. 5422
    “…We examined strength training engagement by middle-aged and older US adults with and without SCD. …”
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    ASSOCIATION BETWEEN SUBJECTIVE COGNITIVE DECLINE AND STRENGTH TRAINING IN US ADULTS AGED 45+ YEARS
  3. 5423
    “…TLR4 knockdown showed a rescue effect in DEP group for Iba-1 and 8-OHdG in young but not in middle-aged mice. Both C5a and 4HNE were rescued by TLR4 knockdown in young and middle-aged mice, possibly with less robust effects in older mice. …”
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    SHORT-TERM DIESEL EXHAUST PARTICLE NEUROTOXICITY MEDIATED BY TLR4 ACROSS AGE AND SEX
  4. 5424
    “…RESULTS: We enrolled 60,911 ICH patients, including 22,284 young and middle‐aged males, 15,651 older males, 11,948 young and middle‐aged females, and 11,028 older females. …”
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    Association of sex and age with in‐hospital mortality and complications of patients with intracerebral hemorrhage: A study from the Chinese Stroke Center Alliance
  5. 5425
    “…This network was explored for association with chronological age, familial longevity and immune-related diseases (type 2 diabetes, chronic obstructive pulmonary disease and rheumatoid arthritis) in 87 nonagenarians, 337 of their middle-aged offspring and 321 middle-aged controls from the Leiden Longevity Study (LLS). …”
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    IL7R gene expression network associates with human healthy ageing
  6. 5426
    “…Preconditioning reduced infarct size in hearts from young control rats and both middle-aged groups, but not from young DIO rats. Age had a significant effect on functional recovery in preconditioning: it was improved in hearts from young control and DIO rats, but depressed in both middle-aged groups. …”
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    Myocardial susceptibility to ischaemia/reperfusion in obesity: a re-evaluation of the effects of age
  7. 5427
    “…MATERIALS AND METHODS: This study included 120 subjects that were divided into three groups according to age: young (20-39 years), middle-aged (40-59 years), and older (over 60 years); and by gender. …”
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    Maximal strength and endurance scores of the tongue, lip, and cheek in healthy, normal Koreans
  8. 5428
    por Shoji, Hirotaka, Miyakawa, Tsuyoshi
    Publicado 2019
    “…RESULTS: Some behavioral changes occurred between young and middle age, and further changes in various behaviors were observed in old age. …”
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    Age‐related behavioral changes from young to old age in male mice of a C57BL/6J strain maintained under a genetic stability program
  9. 5429
    por Hu, Ying, LV, Fajin, Li, Qi, Liu, Rongbo
    Publicado 2020
    “…CONCLUSION: Young people are less affected by PLDs than middle-aged and elderly people. The middle-aged people are most affected by PLDs. …”
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    Effect of post-labeling delay on regional cerebral blood flow in arterial spin-labeling MR imaging
  10. 5430
    “…BACKGROUND: It is unclear that whether childhood neighborhood relationship is associated with mental health among middle-aged and older adults. To overcome this research gap, this study aimed to investigate the association between childhood neighborhood relationship and mental health among the middle-aged and older adults in China. …”
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    The association between childhood neighborhood relationship and mental health in middle and later life: Evidence from the China Health and Retirement Longitudinal Study
  11. 5431
    “…CONCLUSION: A low prevalence of oral hygiene behaviors among middle-aged and elderly Iranian adults was observed. …”
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    Socioeconomic-related inequalities in oral hygiene behaviors: a cross-sectional analysis of the PERSIAN cohort study
  12. 5432
    “…Middle-aged patients were more concerned about computer security than any other group. …”
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    Impact of Age on Patients’ Communication and Technology Preferences in the Era of Meaningful Use: Mixed Methods Study
  13. 5433
    “…RESULTS: Young and middle-aged women did not differ in AT-IR (3.5±2.7 and 3.2±2.1, respectively). …”
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    Determinants and correlates of adipose tissue insulin resistance index in Japanese women without diabetes and obesity
  14. 5434
    “…Objectives: Examine trends in limitations among young (15–39), middle-aged (40–64) and older age-groups (>=65) and their socioeconomic differences. …”
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    Trends in Activity Limitations From an International Perspective: Differential Changes Between Age Groups Across 30 Countries
  15. 5435
    por Ratts, Robert B., Weng, Nan-Ping
    Publicado 2012
    “…As expected, young donors had more T cell receptor excision circles (TRECs), CD31{}(+) cells (CD4 only) and longer telomeres in T cells than did the middle-aged donors. Interestingly, more variation in TREC number, Vβ usages, and telomere lengths were observed in young donors during the 3–5 years course of donation whereas the middle-aged/old donors showed a rather striking stability in these measurements. …”
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    Homeostasis of lymphocytes and monocytes in frequent blood donors
  16. 5436
    por Dunneram, Yashvee, Jeewon, Rajesh
    Publicado 2013
    “…A survey-based study was conducted in 2012 among Indo-Mauritian women including 117 young (21.35 ± 1.98), 160 reaching middle age (34.02 ± 5.09) and 50 middle-aged (37.85 ± 8.32). …”
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    A Scientific Assessment of Sociodemographic Factors, Physical Activity Level, and Nutritional Knowledge as Determinants of Dietary Quality among Indo-Mauritian Women
  17. 5437
    “…CONCLUSIONS: The reduction in lower extremity muscle strength occurs in the middle-age group. We recommend that middle-age women be conscious of the reduction in their lower extremity muscle strength and conduct advanced preparations for future aging.…”
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    Does functional fitness decline in accordance with our expectation? – a pilot study in healthy female
  18. 5438
    por Jones, Chris I.
    Publicado 2016
    “…Platelet count remains relatively stable during middle age (25–60 years old) but falls in older people. …”
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    Platelet function and ageing
  19. 5439
    “…Few studies involving the cognition of middle-aged adults are available in the international literature, particularly investigating the process of cognitive aging, executive components and attention. …”
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    Executive functions and sustained attention: Comparison between age groups of 19-39 and 40-59 years old
  20. 5440
    “…Finally, we found that the relative abundances of Firmicutes and Bacteroidetes were significantly decreased and increased, respectively, in young MDD patients as compared with young HCs, and the relative abundances of Bacteroidetes and Actinobacteria were significantly decreased and increased, respectively, in middle-aged MDD patients as compared with middle-aged HCs. …”
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    Age-specific differential changes on gut microbiota composition in patients with major depressive disorder
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