“…Participants were divided into 6 groups based on sex and age (less than 45 years old (young), aged 45–64 years (middle-aged), and 65 years or older (old)) as follows: male, young (n = 136); middle-aged (n = 133); old (n = 82); female, young (n = 159); middle-aged (n = 228); and old (n = 157). …”
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“…Moreover, depression was associated with nutrient intake and dietary habits by gender and age group: sugar, breakfast, lunch, and eating out frequency in the young women’s group; sodium and lunch frequency among middle-age men; dietary fibers, breakfast, and eating out frequency among middle-age women; energy, moisture, carbohydrate, lunch, and dinner frequency in late middle-age men; breakfast and lunch frequency among late middle-age women; vitamin A, carotene, lunch, and eating out frequency among older age men; and fat, saturated fatty acids, omega-3 fatty acid, omega-6 fatty acid, and eating out frequency among the older age women’s group (p-value < 0.05). …”
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“…Additionally, when weight was accounted for, there was a significant relationship between MetS and select executive functioning tasks in middle-aged adults. These findings suggest that aspects of executive functioning may be impaired in MetS and could be further impacted by excess weight in middle-age. …”
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“…The strongest known risk factors for late-onset Alzheimer disease (LOAD) remain a positive family history and the APOE ε4 allele. van Exel and colleagues used these known risk factors to identify high- and low-risk samples of middle-aged persons in whom they compared levels of inflammatory and vascular risk factors. …”
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“…Mean GH exposure was greater in women than men, and in middle-aged than older women (FAS); it increased slightly over time in all groups. …”
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“…Interhemispheric EEG asymmetry was more evident in middle-aged than in young ischemic rats, and this could tentatively explain the behavioral asymmetry. …”
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“…OBJECTIVES: Adiposity in middle age is an established risk factor for cardiovascular disease and type 2 diabetes; less is known about the impact of adiposity from early adult life. …”
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“…Specifically, we demonstrate that astrocyte defects occur in the hippocampal area of middle‐aged Tet‐mev‐1 mice with the SDHC(V69E) mutation. …”
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“…HFpEF is especially prevalent in elderly women and preceded in middle age by preclinical left ventricular (LV) diastolic dysfunction. …”
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“…At the site scale, the species dissimilarity and turnover both enlarged with increasing slope position difference, especially in the middle-aged community, but the species nestedness had no consistent trend among sites, except a decreasing trend in the middle-aged forest. …”
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“…Methods: Elderly and middle-aged persons with no acute disease or severe chronic disorder were assessed. …”
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“…RESULTS: Older adults reported lower levels of anxiety and sadness than middle aged adults, and middle aged adults reported lower levels than younger participants. …”
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“…BACKGROUND: Although middle-aged adults in Korea are vulnerable to depression, there are few preventive interventions for depression in middle adulthood. …”
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“…Middle-aged patients with APM score lower in all subscales than the normal population (p≤0.009). …”
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“…There was also no difference in OS (HR: 0.6, 95% CI: 0.3–1.3) for middle-aged patients. However, middle-aged patients had low recurrence rates (HR: 0.5, 95% CI: 0.3–0.8). …”
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“…We found that synaptic tagging was impaired in the ACC of middle-aged male mice as compared to adult mice. Both the network late-phase LTP (L-LTP) and the recruitment of inactive responses were reduced in the ACC of middle-aged male mice. …”
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“…BACKGROUND: A surge in suicide rates in middle age people in Hong Kong and many Asian countries was recently observed. …”
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“…Age-related memory decline including spatial reference memory is considered to begin at middle-age and coincides with reduced adult hippocampal neurogenesis. …”
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“…Objective To compare sagittal cervical range of motion (ROM) and alignment in young versus middle-aged adults. Methods One hundred four asymptomatic adults were selected randomly out of 791 subjects who underwent lateral cervical radiographs in neutral, flexion, and extension positions. …”
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“…However, not all of the findings were replicated in the two middle-aged cohorts. CONCLUSION: Our data provides a novel insight into the inconsistent genetic determinants between middle-aged and LLI subjects. …”
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