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  1. 5741
    “…We also found sex-dependent differences that were more pronounced in younger adults than in middle-aged adults, with women having higher alpha diversity than men. …”
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    Age- and Sex-Dependent Patterns of Gut Microbial Diversity in Human Adults
  2. 5742
    “…BACKGROUND: Middle-aged and older adults with mental health conditions have a high likelihood of experiencing comorbid physical health conditions, premature nursing home admissions, and early death compared with the general population of adults aged 50 years or above. …”
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    Older Adult Peer Support Specialists’ Age-Related Contributions to an Integrated Medical and Psychiatric Self-Management Intervention: Qualitative Study of Text Message Exchanges
  3. 5743
    “…METHODS: In this 4-year multicenter case-control study, patients with community-onset bacteremia were retrospectively categorized into the “middle-aged” (45–64 years), “old” (65–74 years), and “very old” (≥75 years) groups. …”
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    Prognostic Effects of Inappropriate Empirical Antimicrobial Therapy in Adults With Community-Onset Bacteremia: Age Matters
  4. 5744
    “…A middle-aged woman suffering from CMV pancreatitis and HIV positive was treated…”
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    Cytomegalovirus-Associated Pancreatitis in Acquired Immunodeficiency Syndrome
  5. 5745
    “…We describe a rare case of angioleiomyoma in the foot of a middle‐aged man.…”
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    Angioleiomyoma of the right forefoot
  6. 5746
    “…Twenty-two patients developed delirium postoperatively (14 older; 8 middle-aged) and 89 proteins in pre- or 1-day postoperative plasma were associated with delirium. …”
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    Age-dependent differences and similarities in the plasma proteomic signature of postoperative delirium
  7. 5747
    “…The risk of BMI for common chronic diseases increased dramatically in middle-aged, especially for men with drinking and smoking habits.…”
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    The dose-response analysis between BMI and common chronic diseases in northeast China
  8. 5748
    “…After 4 weeks of induction, aortic diameter was significantly increased and excessive Mac3-positive inflammatory cells infiltrated the destroyed aorta in middle-aged mice. AAA-induced middle-aged mice further exhibited cognitive impairment. …”
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    Establishment of Novel Murine Model showing Vascular Inflammation-derived Cognitive Dysfunction
  9. 5749
    “…OBJECTIVES: We aimed to compare the association of body mass index (BMI), waist circumference (WC), and waist‐to‐height ratio (WHtR) with risk of cardiovascular disease (CVD) among middle‐aged working Japanese men. METHODS: A nested case‐control study was performed among middle‐aged male employees who underwent periodic health checkup. …”
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    Association between anthropometric indices of obesity and risk of cardiovascular disease in Japanese men
  10. 5750
    “…BACKGROUND: Middle-aged and older adults are more vulnerable to hospitalization and mortality if they are infected with the COVID-19 virus. …”
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    Effects of subjective successful aging on emotional and coping responses to the COVID-19 pandemic
  11. 5751
    “…We compared the differences in clinical outcomes for younger and older surgeons compared to middle-aged surgeons. Subgroup analyses were performed for major and minor surgery. …”
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    Association between surgeon age and postoperative complications/mortality: a systematic review and meta-analysis of cohort studies
  12. 5752
    “…Tissues were also excised from younger (3‐month‐old) and middle‐aged (15‐month‐old) mice. Microarray analysis of RNA was performed using tibialis anterior (TA) muscles from middle‐aged mice, and some genes were further tested using RT‐PCR. …”
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    Angiotensin‐converting enzyme 2 deficiency accelerates and angiotensin 1‐7 restores age‐related muscle weakness in mice
  13. 5753
    “…MUS were higher in the middle age group than in the low age group. No significant difference existed between the two groups and the high age group. …”
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    Differences of medically unexplained symptoms among patients of different ages and sexes in the psychological clinic of a general hospital and the influencing factors of MUS: A cross-sectional study
  14. 5754
    “…The majority of cases are reported in middle-aged Asian males and rarely seen in other ethnicities. …”
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    A rarely described Kimura’s disease of the breast
  15. 5755
    “…Obstructive sleep apnea (OSA) occurs in 2% of middle-aged women and 4% of middle-aged men with a higher prevalence among obese subjects. …”
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    Cardiovascular Complications of Sleep Apnea: Role of Oxidative Stress
  16. 5756
    “…Pilomatrixoma of the eyelid is extremely rare in middle age and rarely develops into a large tumor. A 45-year-old female developed a painless, progressive swelling (3.0 cm × 2.0 cm) of the left upper eyelid over a period of two years. …”
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    A giant upper eyelid ossifying pilomatrixoma
  17. 5757
    “…BACKGROUND: Cellular angiofibroma, first described in 1997, is known to occur in both genders with equal predilection occurring in middle aged females and older males. CASE PRESENTATION: In this study, a case of vaginal cellular angiofibroma was reported in a 30 year old female presenting with secondary infertility. …”
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    Cellular Angiofibroma of Vagina Presenting with Secondary Infertility
  18. 5758
    “…Obstructive sleep apnea (OSA) occurs in 2% of middle-aged women and 4% of middle-aged men and is considered an independent risk factor for cerebrovascular and cardiovascular diseases. …”
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    Nitric Oxide Bioavailability in Obstructive Sleep Apnea: Interplay of Asymmetric Dimethylarginine and Free Radicals
  19. 5759
    “…NAM is a rare disease that typically affects middle-aged Caucasian women. In this case report, we present the diagnosis of anti-SRP NAM in a middle-aged African American male. …”
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    Anti-signal Recognition Particle Necrotizing Autoimmune Myopathy: An Atypical Presentation
  20. 5760
    por Wang, Guanyu
    Publicado 2020
    “…Moderate middle-age spread is thus natural, not an anomaly caused by hypothalamic defects, as proposed by lipostatic theory. …”
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    Body Mass Dynamics Is Determined by the Metabolic Ohm's Law and Adipocyte-Autonomous Fat Mass Homeostasis
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