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  1. 6161
    “…[Purpose] The aim of this study was to determine how compound physical activity affects muscular strength of middle-aged obese women. [Subjects] The research subjects were 40–50 year-old middle-aged women with excess body fat (30%). …”
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    A Study of Effect of the Compound Physical Activity Therapy on Muscular Strength in Obese Women
  2. 6162
    “…Low vitality (a component of fatigue) in middle-aged and older adults is an important complaint often identified as a symptom of a disease state or side effect of a treatment. …”
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    Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells
  3. 6163
    “…Using another mouse model of type 2 diabetes generated by high-fat diet (HFD) feeding and low doses of streptozotocin injection, we found that baicalein treatment significantly improved hyperglycemia, glucose tolerance, and blood insulin levels in these middle-aged obese diabetic mice, which are associated with the improved islet β-cell survival and mass. …”
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    Baicalein Protects against Type 2 Diabetes via Promoting Islet β-Cell Function in Obese Diabetic Mice
  4. 6164
    “…We investigated whether middle-aged type 2 diabetic patients show these brain activity patterns during encoding and recognition tasks. …”
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    Task-Induced Brain Activity Patterns in Type 2 Diabetes: A Potential Biomarker for Cognitive Decline
  5. 6165
    “…The relationship between dairy consumption and insulin resistance was ascertained in 272 middle-aged, nondiabetic women using a cross-sectional design. …”
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    Dairy Consumption and Insulin Resistance: The Role of Body Fat, Physical Activity, and Energy Intake
  6. 6166
    “…Objective: To explore potential risk factors of isolated diastolic hypertension (IDH) among young and middle-aged Chinese. Methods: A community-based cross-sectional study was conducted among 338 subjects, aged 25 years and above, using random sampling technique. …”
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    Isolated Diastolic Hypertension Associated Risk Factors among Chinese in Anhui Province, China
  7. 6167
    por Morgan, Todd E., Finch, Caleb E.
    Publicado 2015
    “…In a perimenopausal model of middle-aged rats, the astrocyte estrogen receptor-alpha (ERa): ER-beta (ERb) ratio increased with the onset of acyclicity (constant estrus, CE) in association with impaired neurotrophic responses to estradiol (E2). …”
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    Astrocytic estrogen receptors and impaired neurotrophic responses in a rat model of perimenopause
  8. 6168
    “…This study compared levels of physical activity (i.e., sedentary behavior, light physical activity (LPA), and moderate-to-vigorous physical activity (MVPA)) and rates of meeting public health guidelines for MVPA (i.e., ≥30 min/day) among young (i.e., ages 20-39 years), middle-aged (i.e., ages 40-59 years) and older adults (i.e., ages ≥60 years) with MS. …”
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    Levels and Rates of Physical Activity in Older Adults with Multiple Sclerosis
  9. 6169
    “…We found that females exhibit an increase in RFamide-related peptide-3 (RFRP3) mRNA expression in the hypothalamus in middle age prior to changes in estrous cycle length. …”
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    The Role of RFamide-Related Peptide-3 in Age-Related Reproductive Decline in Female Rats
  10. 6170
    por Simon, Ellin, Verboon, Peter
    Publicado 2016
    “…Insight into the usefulness of measuring psychological flexibility is an important step to enable studies on the effectiveness of acceptance commitment therapy in middle-aged children (8–10 years). For this purpose, we examined the factor structure, the construct validity and the reliability of the Avoidance and Fusion Questionnaire for Youth. …”
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    Psychological Inflexibility and Child Anxiety
  11. 6171
    “…This cross-sectional study investigated the age-related differences in dual-task performance both in mobility and cognitive tasks and the additive dual-task costs in a sample of older, middle-aged and young adults. 74 older adults (M = 72.63±5.57 years), 58 middle-aged adults (M = 46.69±4.68 years) and 63 young adults (M = 25.34±3.00 years) participated in the study. …”
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    Age-related decrements in dual-task performance: Comparison of different mobility and cognitive tasks. A cross sectional study
  12. 6172
    “…These results indicate that LCGT intake can reduce stress in middle-aged individuals and improve their quality of sleep. …”
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    Reduced Stress and Improved Sleep Quality Caused by Green Tea Are Associated with a Reduced Caffeine Content
  13. 6173
    “…The explained variance in health in older people by the social network and SEP was only half of the explained variance observed in middle-aged people, suggesting that other factors than SEP were more important for health when people age. …”
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    Social pathways to health: On the mediating role of the social network in the relation between socio-economic position and health
  14. 6174
    por Park, So Hyun, Kim, Seong-Gil
    Publicado 2018
    “…METHODS: Subjects (n = 571) were classified into 3 groups by age; young (18–39 years), middle aged (40–64 years), and old aged (≥ 65 years). …”
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    Comparison of Hypertension Prediction Analysis Using Waist Measurement and Body Mass Index by Age Group
  15. 6175
    “…Our results demonstrate that the increase in circulating ROS and protein carbonyl content occurs as early as middle age. Moreover, increased 8-OHdG in the liver of 15-month-old rats was at least in part associated with a reduced DNA damage repairing capacity as suggested by the down-regulation of APE1 gene expression. …”
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    Aging related changes in circulating reactive oxygen species (ROS) and protein carbonyls are indicative of liver oxidative injury
  16. 6176
    “…Methods: A total of 100 middle-aged (M(AGE) = 48.07; SD = 5.27; 53% female) and 100 older-aged participants (M(AGE) = 70.89; SD = 5.97; 51% female) completed the 40-item Narcissistic Personality Inventory and the UCLA Loneliness Scale, Version 3. …”
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    The Aging Narcissus: Just a Myth? Narcissism Moderates the Age-Loneliness Relationship in Older Age
  17. 6177
    “…In addition, comparing to the 0-4-year age-group, odds of death were significantly higher in middle aged and elderly victims.   CONCLUSION: Our findings showed that middle age groups, male gender and urban area increase the odds of death. …”
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    Epidemiologic Aspects of Overall Injuries in Hamadan Province; A Six-Year Registry-Based Analysis
  18. 6178
    “…RMO is most commonly observed in middle-aged men, and its etiology is unknown. We report the case of a middle-aged man who experienced repeated low back pain that was caused by RMO of the sacroiliac joint (SIJ). …”
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    Repeated Low Back Pain Caused by Regional Migratory Osteoporosis of the Sacroiliac Joint
  19. 6179
    “…Treatment of middle-aged females with an ERα agonist did not recover the positive actions of exercise. …”
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    Loss of the interaction between estradiol and insulin-like growth factor I in brain endothelial cells associates to changes in mood homeostasis during peri-menopause in mice
  20. 6180
    “…The present study is aimed at assessing the effect of MOI on aging-associated alteration of the endothelial function in Wistar rats. Middle-aged Wistar rats (46-week-old males) have been fed with food containing or not 750 mg/kg/day of MOI seed powder for 4 weeks. …”
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    Moringa oleifera Seeds Improve Aging-Related Endothelial Dysfunction in Wistar Rats
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