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  1. 10641
    “…Here, we show that middle-aged Tet2 knockdown (Tet2(gt/gt)) mice exhibit Tfh-like cell overproduction in the spleen compared with control mice. …”
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    Reduced TET2 function leads to T-cell lymphoma with follicular helper T-cell-like features in mice
  2. 10642
    por Joh, Hee-Kyung, Oh, Seung-Won, Lee, Eun
    Publicado 2015
    “…CONCLUSIONS: Our findings suggest that the developed FFQ is reproducible and reasonably valid in categorizing individuals according to TFA intakes among healthy young and middle aged adults in Korea.…”
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    Reproducibility and validity of semi-quantitative food frequency questionnaire measuring dietary trans-fatty acids intake among Korean adults
  3. 10643
    “…It usually involves the head, neck or the back of a middle-age person. To the best of our knowledge, two ocular cases have been reported in the literature. …”
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    Superficial epithelioma with sebaceous differentiation involving the eyelid: a case report
  4. 10644
    “…Although 17β-estradiol (E(2)) deficiency has been linked to the development of osteoarthritis (OA) in middle-aged women, there are few studies relating other estrogens and estrogen metabolites (EMs) to this condition. …”
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    Measurement of serum estrogen and estrogen metabolites in pre- and postmenopausal women with osteoarthritis using high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry
  5. 10645
    “…CONCLUSION: Bodyboarding tended to induce spinal cord injuries after the head or face collided with the sea bottom, and was more common in middle-aged males during the summer season, and was associated with a favorable outcome.…”
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    Analysis of patients with bodyboarding injuries transported by physician-staffed emergency helicopter
  6. 10646
    “…There is mounting evidence that HIV exacerbates age-associated cognitive decline. Many middle-aged HIV-infected people are experiencing cognitive decline similar that to that found among much older adults. …”
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    HIV effects on age-associated neurocognitive dysfunction: premature cognitive aging or neurodegenerative disease?
  7. 10647
    “…Objectives: This article aims to contribute to the literature on life course influences upon quality of life by examining pathways linking social position in middle age to quality of life following retirement in French men and women. …”
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    Mid-life occupational grade and quality of life following retirement: a 16-year follow-up of the French GAZEL study
  8. 10648
    “…CONCLUSION: Public policies for the prevention and management of diabetes should be targeted toward people of lower SES, especially middle-aged females.…”
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    Effect of Socio-Economic Status on the Prevalence of Diabetes
  9. 10649
    “…BACKGROUND: Oral squamous cell carcinoma (OSCC) constitutes 3 percent of all cancers with predominant occurrence in middle aged and elderly males. Tumour recurrence worsens disease prognosis and decreases quality of life in patients with OSCC. …”
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    Evaluation of pretreatment serum interleukin-6 and tumour necrosis factor alpha as a potential biomarker for recurrence in patients with oral squamous cell carcinoma
  10. 10650
    “…CONCLUSIONS: Dietary MFGM supplementation combined with regular exercise improves skeletal muscle strength, which may be due to increased motor unit recruitment in healthy Japanese middle-aged adults.…”
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    Dietary milk fat globule membrane supplementation combined with regular exercise improves skeletal muscle strength in healthy adults: a randomized double-blind, placebo-controlled, crossover trial
  11. 10651
    por Uitenbroek, Daan G.
    Publicado 2015
    “…Differences in survival between ethnic groups are small up to middle age.…”
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    Use of the life table to compare mortality in ethnic groups in Amsterdam, the Netherlands
  12. 10652
    “…To determine the effect of long-term exercise on PLINs expression, 26 middle-aged, sedentary men underwent 12 weeks combined endurance and strength training intervention. …”
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    Perilipin 4 in human skeletal muscle: localization and effect of physical activity
  13. 10653
    “…Young respondents were less likely to object than were middle-aged respondents, in both the first (AOR = 0.648) and second (AOR = 0.572) scenarios. …”
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    Demographic and Socioeconomic Factors Influencing Public Attitudes Toward a Presumed Consent System for Organ Donation Without and With a Priority Allocation Scheme
  14. 10654
    “…We show that the decrease of DCX+ cells causes impaired social discrimination ability in both young adult (from 3 months) and middle aged (from 10 months) mice. Furthermore, these animals showed an age-independent altered coping behavior in the Forced Swim Test without clear changes in anxiety-related behavior. …”
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    Conditional Reduction of Adult Born Doublecortin-Positive Neurons Reversibly Impairs Selective Behaviors
  15. 10655
    “…The objective of this study was to assess the association among middle-aged and older Chinese women. We used data from the Dongfeng-Tongji Cohort Study. …”
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    Parity and Risk of Stroke among Chinese Women: Cross-sectional Evidence from the Dongfeng-Tongji Cohort Study
  16. 10656
    “…Moreover, TAT-ASCs from elderly subjects showed higher adipogenic and osteogenic capacities compared to middle aged subjects, indicating that, rather than impairing; aging seems to increase adipogenic and osteogenic capacities of TAT-ASCs. …”
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    Myocardial Ischemic Subject’s Thymus Fat: A Novel Source of Multipotent Stromal Cells
  17. 10657
    “…However, combined EE-EGCG significantly ameliorated learning alterations of middle age Ts65Dn mice. Interestingly, PCA revealed an increased variability along learning sessions with good and poor learners in Ts65Dn, and this stratification did not disappear upon treatments. …”
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    Principal Component Analysis of the Effects of Environmental Enrichment and (-)-epigallocatechin-3-gallate on Age-Associated Learning Deficits in a Mouse Model of Down Syndrome
  18. 10658
    “…Multiple sclerosis is the most common chronic disabling disease in the central nervous system in young to middle aged adults. Depression is common in multiple sclerosis (MS) affecting between 50–60% of patients. …”
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    Omega-3 Fatty Acids for Depression in Multiple Sclerosis: A Randomized Pilot Study
  19. 10659
    “…Short-term incidence of AMI (6-month prior vs 6 months after the smoking ban) was also reduced (4.5%, 95% CI 0.2% to 9.0%; p=0.0399) and was largest in the working middle-aged group (40–50 years) but observed also in the oldest age group (>70 years). …”
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    Association of restaurant smoking ban and the incidence of acute myocardial infarction in Finland
  20. 10660
    “…The majority of respondents were male (88.4 %), middle-aged (65.3 %), and worked as family physicians (56.1 %). …”
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    Change of government’s subsidization policy improves smoking cessation services: a cross-sectional study from the perspectives of physicians
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