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  1. 10841
    “…CASE DESCRIPTION: The authors describe a case report on similar lines of a middle aged gentleman presenting with low back pain and weakness in both lower limbs which on further investigations revealed a pathological fracture causing spinal cord compression due to metastasis from small cell carcinoma in the lungs, managed with surgical intervention, and subsequently with radiotherapy. …”
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    Metastatic small cell neuroendocrine tumor with spinal cord compression – Understanding a rare entity
  2. 10842
    “…The present study aimed to biochemically and morphometrically characterize the intrinsic neurons in ovaries from young adult, middle-aged, and senescent Long Evans CII-ZV rats (3, 12, and 15 months old, respectively). …”
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    Intrinsic innervation of the ovary and its variations in the rat senescence process
  3. 10843
    “…RESULTS: 10% of nail lesions referred to Razi Hospital (RH), and 30% of nail lesions referred to TUMS mycology laboratory were positive. Middle age (40–60) suffer more from onychomycosis. Aspergillus flavus, Trichophyton mentagrophytes, and Candida albicans were the most common etiologic agents in each of the three main classes of fungi causing onychomycosis. …”
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    The epidemiology and etiology of onychomycosis in 2 laboratory centers affiliated to Tehran university of medical sciences during 2019–2020
  4. 10844
    “…Deceased patients were mostly young or middle-aged without known systemic diseases or epilepsy. …”
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    Factors associated with mortality in patients with super-refractory status epilepticus
  5. 10845
    “…METHODS: We conducted a cross-sectional study in a middle-aged cohort of Maltese Caucasian non-institutionalized population. …”
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    Prevalence rates of metabolic health and body size phenotypes by different criteria and association with insulin resistance in a Maltese Caucasian population
  6. 10846
    “…Rare variants affecting host defense against pathogens could be involved in COVID-19 severity and may help explain fatal outcomes in young and middle-aged patients. Our aim was to report the presence of rare genetic variants in certain genes, by using whole exome sequencing, in a selected group of COVID-19 patients under 65 years who required intubation or resulting in death (n = 44). …”
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    Presence of rare potential pathogenic variants in subjects under 65 years old with very severe or fatal COVID-19
  7. 10847
    “…Diabetes often occurs in middle-aged and elderly people. However, there is growing evidence that the incidence rate of young body is increasing over the years. …”
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    Linking Mitochondrial Function to Insulin Resistance: Focusing on Comparing the Old and the Young
  8. 10848
    “…It has been inaccurately considered a pathological condition affecting only middle-aged women. The study aimed to explore the association of sociodemographic and clinical factors in patients with fibromyalgia with depression and/or anxiety. …”
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    Patients With Fibromyalgia, Depression, and/or Anxiety and Sex Differences
  9. 10849
    “…The prevalence of BPPV is found to be higher among middle-aged women. Objectives  To estimate the serum levels of calcium and vitamin D in patients with BPPV, and to study their association. …”
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    Association of Serum Calcium and Vitamin D with Benign Paroxysmal Positional Vertigo
  10. 10850
    “…RESULTS: Third‐party callers were most likely to be calling about a family member or friend and were significantly more likely than persons at risk to be female and middle‐aged or older. Counselors were able to collect information about suicide risk, and counselors and third‐parties were nearly always able to identify at least one intervention to aid the person at risk. …”
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    Third‐party callers to the national suicide prevention lifeline: Seeking assistance on behalf of people at imminent risk of suicide
  11. 10851
    “…Heart failure (HF) and cancer are responsible for 50% of all deaths in middle-aged people. These diseases are tightly linked, which is supported by recent epidemiological studies and case control studies, demonstrating that HF patients have a higher risk to develop cancer such as lung and breast cancer. …”
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    Evidence for reciprocal network interactions between injured hearts and cancer
  12. 10852
    “…We demonstrated that Sema3F‐transduced HSCs stimulate OPC migration in a neuropilin 2 (Nrp2, Sema3F receptor)‐dependent fashion, which was conserved in middle‐aged OPCs. While demyelinating lesions induced in mice with Sema3F‐expressing blood cells showed no changes in inflammation and OPC survival, OPC recruitment was enhanced which accelerated the onset of remyelination. …”
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    Genetically modified macrophages accelerate myelin repair
  13. 10853
    “…CASE PRESENTATION: The patient was a middle-aged housewife who had been using the household spray for a long time, and the main symptoms were cough and sputum production. …”
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    A Rare Case of Post-Primary Tuberculosis Which Was Pathologically Diagnosed as Lipoid Pneumonia
  14. 10854
    “…The aim of this study was to evaluate the association between gamma-glutamyl transferase (GGT) levels and the risk of hip fracture among middle-aged women by using the Korean National Health Insurance Service claims database from 2002 to 2015. …”
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    Elevated gamma-glutamyl transpeptidase level is associated with an increased risk of hip fracture in postmenopausal women
  15. 10855
    por Yamaguchi, Takeshi, Masani, Kei
    Publicado 2022
    “…Participants were divided into three groups: young, middle-aged, and old. The step width of the old group was higher than that of the young group. …”
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    Effects of age on dynamic balance measures and their correlation during walking across the adult lifespan
  16. 10856
    “…It is the primary feature of obesity in middle-aged and elderly individuals. In the adipose microenvironment, a high level of endoplasmic reticulum (ER) stress and changes in the extracellular vesicle (EV) composition of adipocytes may cause the senescence and restrained differentiation of progenitor cells of adipose, including adipose-derived mesenchymal stem cells (ASCs). …”
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    Transmissible Endoplasmic Reticulum Stress Mediated by Extracellular Vesicles from Adipocyte Promoting the Senescence of Adipose-Derived Mesenchymal Stem Cells in Hypertrophic Obesity
  17. 10857
    “…METHODS: In initially cognitively unimpaired, late middle‐aged participants (N = 1215; baseline age, M [standard deviation] = 59.3 [6.7] years) from the Wisconsin Registry for Alzheimer's Prevention (WRAP), we investigated the influence of the Lifestyle for Brain Health (LIBRA) index, a lifestyle‐based dementia risk score, on AD‐related cognitive trajectories and amyloid beta (Aβ) plaque accumulation. …”
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    Associations of the Lifestyle for Brain Health index with longitudinal cognition and brain amyloid beta in clinically unimpaired older adults: Findings from the Wisconsin Registry for Alzheimer's Prevention
  18. 10858
    “…We held focus group discussions (18) and interviews (44) with younger and middle-aged men and women from the general population and female sex workers (FSWs) in selected communities in Ibadan. …”
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    Heterosexual Oral and Anal Sex: Perceptions, Terminologies, and Attitudes of Younger and Older Adults in Ibadan, Nigeria
  19. 10859
    “…We confirmed that both younger and older individuals performed worse (less and smaller eggs) than middle-aged individuals. Our ensemble training algorithm was only able to distinguish young individuals, but not senescent breeders. …”
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    Inferring the age of breeders from easily measurable variables
  20. 10860
    “…In this study, we explored the performance of older adults, middle-aged adults, and younger controls in a task assisted by the referential gaze of a Pepper robot. …”
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    Age-Related Differences in the Perception of Robotic Referential Gaze in Human-Robot Interaction
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