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  1. 11061
    “…The present study shows that aging progranulin deficient mice develop progressive polydipsia and polyuria under standard housing conditions starting at middle age (6-9 months). They showed high water licking behavior and doubling of the normal daily drinking volume, associated with increased daily urine output and a decrease of urine osmolality, all maintained during water restriction. …”
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    Progranulin Deficient Mice Develop Nephrogenic Diabetes Insipidus
  2. 11062
    “…A single-center, randomized, controlled, 3-arm, 6 h, crossover study was conducted in overweight/obese middle-aged adults (n = 31). Participants consumed energy-matched breakfast meals containing 0 g (Control), 68 g (Half-A) or 136 g (Whole-A) fresh Hass avocado on 3 separate occasions. …”
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    Avocado Fruit on Postprandial Markers of Cardio-Metabolic Risk: A Randomized Controlled Dose Response Trial in Overweight and Obese Men and Women
  3. 11063
    “…RESULTS: A total of 223 (170 males and 53 females) middle-aged (50.9 ± 9 years old) liver transplant recipients were included in this study. …”
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    Prevalence and Prognosis of Portopulmonary Hypertension in 223 Liver Transplant Recipients
  4. 11064
    “…Because ischemic stroke is a more critical health problem in East Asian than in other populations, in order to clarify pathological changes underlying cerebral small vessel disease (SVD), we projected an imaging analysis of LSA using high-resolution brain magnetic resonance imaging (MRI) in middle-aged Japanese subjects with type 2 diabetes. …”
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    Evaluation of Lenticulostriate Arteries Changes by 7 T Magnetic Resonance Angiography in Type 2 Diabetes
  5. 11065
    por Riccioni, Graziano
    Publicado 2012
    “…Coronary artery diseases (CAD) represent the most common cause of death in middle–aged and older adults in European Countries. …”
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    Ivabradine: An Intelligent Drug for the Treatment of Ischemic Heart Disease
  6. 11066
    “…The ages of the groups were as follows: 26 young adults (20–30 y, 25.2±3.03), 26 middle-aged adults (35–50 y, 39.46±6.97) and 26 older adults (60 y or older, 69.80±10.01). …”
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    Age-dependent Changes in Plasma Amino Acids Contribute to Alterations in Glycoxidation Products
  7. 11067
    “…Twenty-one features were extracted from PPW that collected from the radial artery, and then a linear regression method was used to develop blood pressure estimation models by using the extracted PPW features. Sixty-five middle-aged and elderly participants were recruited to evaluate the performance of the constructed blood pressure estimation models, with oscillometric technique-based blood pressure as a reference. …”
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    Cuffless Blood Pressure Estimation Using Pressure Pulse Wave Signals
  8. 11068
    por Carvajal, Manuel J., Popovici, Ioana
    Publicado 2018
    “…Age has a U-shape effect on job satisfaction, with middle-age pharmacists less satisfied than both younger and older practitioners. …”
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    Gender, age, and pharmacists’ job satisfaction
  9. 11069
    “…CONCLUSION: We present a case report of a rare adrenal tumor in a middle-aged woman that manifested as acute coronary syndrome. …”
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    Pheochromocytoma-related cardiomyopathy presenting as broken heart syndrome: Case report and literature review
  10. 11070
    “…BACKGROUND: Both biological and social mechanisms have been implicated in the transmission of suicidal behavior in younger and middle-aged adults. Yet, while suicide rates rise with age, it is not clear whether such mechanisms operate in late life. …”
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    Familial and social transmission of suicidal behavior in older adults
  11. 11071
    “…Aim of the work: Massive rotator cuff tears are a common source of shoulder pain and dysfunction, especially in middle age patient; these lesions represent about 20% of all rotator cuff tears and 80% of recurrent tears. …”
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    Partial repair in irreparable rotator cuff tear: our experience in long-term follow-up
  12. 11072
    “…Participants were primarily male, middle-aged, married with children, and had worked in e-waste recycling for an average of 12 years. …”
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    Health Assessment of Electronic Waste Workers in Chile: Participant Characterization
  13. 11073
    “…Sport is a potential venue for more middle-aged adults to engage in sufficient physical activity for health benefits. …”
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    Gain-Framed Messaging for Promoting Adult Sport: Examining the Effects of Efficacy-Enhancing Information
  14. 11074
    “…The unexpected finding that half of the identified SPCs were typical late onset cancers in the middle-aged population raises concerns that therapy may facilitate premature aging. …”
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    Second cancers and causes of death in patients with testicular cancer in Sweden
  15. 11075
    “…The aim of the present study is to evaluate the effects of TSG treatment on middle-aged (12-mo-old) male LDLr(−/−) mice, which were fed a high fat diet for 12 weeks to induce metabolic syndrome and NASH. …”
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    2, 3, 4′, 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms
  16. 11076
    “…This injury usually presents in middle aged people with a history of chronic illness. …”
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    Atraumatic acute bilateral quadriceps tendon rupture in a patient with bilateral patella spurs. A case report and review of literature
  17. 11077
    “…Based on long-term observation data, we found that males predominated the majority of A(H7N9)-infected individuals and that most males were middle-aged or elderly. Further, wavelet analysis was used to detect the variation in time-frequency between A(H7N9) cases and meteorological factors. …”
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    Identifying Risk Factors Of A(H7N9) Outbreak by Wavelet Analysis and Generalized Estimating Equation
  18. 11078
    “…However, even under resource-limited conditions, immune challenge had no effect on the reproductive output of young or middle-aged females. Both reproductive output and immune function (lysozyme-like activity and phenoloxidase (PO) activity) increased with age, which is contrary to both hypotheses. …”
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    Immunity for nothing and the eggs for free: Apparent lack of both physiological trade-offs and terminal reproductive investment in female crickets (Gryllus texensis)
  19. 11079
    “…This study investigated the correlation of dietary patterns with components of dyslipidemia and fasting plasma glucose (FPG) among young and middle-aged adults (aged between 20 and 50 years) with dyslipidemia and abnormal FPG in Taiwan. …”
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    Dietary Patterns in Relation to Components of Dyslipidemia and Fasting Plasma Glucose in Adults with Dyslipidemia and Elevated Fasting Plasma Glucose in Taiwan
  20. 11080
    “…We found no significant treatment effect on BTMs, BMD, or TBS (p > 0.05 for all). In middle-aged healthy men, vitamin D treatment for 12 weeks had no significant effect on BTMs or BMD.…”
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    Effects of Vitamin D Supplementation on Bone Turnover and Bone Mineral Density in Healthy Men: A Post-Hoc Analysis of a Randomized Controlled Trial
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