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  1. 11241
    “…Because of its occurrence in middle age, the impact on spouses is particularly marked and dyadic-based interventions are recommended. …”
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    Music and Psychology & Social Connections Program: Protocol for a Novel Intervention for Dyads Affected by Younger-Onset Dementia
  2. 11242
    “…Helping behaviors and life satisfaction generally increase after middle-age. Identifying the neural substrates of prosocial behaviors in older adults may offer additional insights into these changes over the lifespan. …”
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    Oxytocin Release Increases With Age and Is Associated With Life Satisfaction and Prosocial Behaviors
  3. 11243
    “…IMPLICATIONS: These findings highlight the long-term effects of childhood experiences on food security generally, and in Appalachia particularly for middle-aged adults. Reducing ACEs could reduce food insecurity and improve health in the region.…”
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    Adult Food Security and the Relationship with Adverse Childhood Experiences Among Residents of Appalachian North Carolina
  4. 11244
    “…Senior participants had a lower frequency of high knowledge answers about H. pylori (43.1%) compared to younger (56.1%) and middle-aged participants (51.5%, p = 0.014). Rural participants had a higher frequency of low knowledge answers compared to urban and suburban ones (21.7% vs. 9.5% and 9.4%, p = 0.011). …”
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    Helicobacter pylori Infection in Croatian Population: Knowledge, Attitudes and Factors Influencing Incidence and Recovery
  5. 11245
    “…Generalized estimating equations were employed to evaluate retention over time as a function of social determinants, health behaviors, and health conditions. Being middle-aged, higher education, and regular exercise were positively associated with retention. …”
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    Retention in Community Health Screening among Taiwanese Adults: A 9-Year Prospective Cohort Study
  6. 11246
    “…A positive and improved response to a gluten-free diet for a limited period of time (e.g., six to eight weeks), followed by retrieval of symptoms in case of gluten intake, is presently considered to be the best strategy for confirmation of diagnosis. A middle-aged lady came for medical attention with concerns of weight loss, lethargy and abdominal discomfort. …”
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    Diagnostic Dilemma, Possible Non-celiac Gluten Sensitivity: Consideration in Approach and Management
  7. 11247
    por Wang, Xueling, Han, Lin, Yang, Jiyuan
    Publicado 2022
    “…BACKGROUND: Coronary heart disease (CHD) has a high incidence rate as a cardiovascular condition, primarily affecting the elderly and middle-aged individuals. CHD has debilitating effects on the standard of life of the elderly, and affecting their physical and psychological health. …”
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    Evaluation of efficacy and safety of aspirin combination treatment in treating patients with coronary heart disease: A protocol for systematic review and meta-analysis
  8. 11248
    por Macovei, Mioara-Laura, Azis, Űnal
    Publicado 2022
    “…Objective: Our aim was to present a rare case of a middle-aged male patient, diagnosed with Graves’ orbitopathy, which had an atypical rapid unilateral onset. …”
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    A case report of a patient with severe thyroid eye disease
  9. 11249
    por Rentería, Elisenda, Zueras, Pilar
    Publicado 2022
    “…Therefore, regional authorities need to pay special attention to the level of investments on health services, as they are clearly associated with a better quality of living of the middle age and older population.…”
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    Macro-level factors explaining inequalities in expected years lived free of and with chronic conditions across Spanish regions and over time (2006–2019)
  10. 11250
    “…It is more common in middle-aged females and is treatable if diagnosed early. …”
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    Atypical Case of Schmidt’s Syndrome in a Young Male
  11. 11251
    “…Different levels of coffee consumption were considered as exposure(s) and comparator(s) according to PECO concepts, while middle age was an inclusion criterion (40+ years). No limitations were set on the tool(s) assessing physical functioning, type of dietary assessment(s), study setting, general health status, country, and observational study design (cohort, cross-sectional). …”
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    Coffee Drinking and Adverse Physical Outcomes in the Aging Adult Population: A Systematic Review
  12. 11252
    por Kim, Young-Joo, Yeom, Hyun-E
    Publicado 2022
    “…METHODS: This study used 2010–2018 panel data from the Korean Longitudinal Study of Aging that assessed sociodemographic and health-related trends in Korean middle-aged to older population. A generalized method of moments estimator of the panel threshold model was applied to estimate the potential nonlinear pattern between BMI and cognitive function. …”
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    Threshold effects of body mass index on cognitive function and heterogeneity by sex and cardiovascular risk factors
  13. 11253
    por Mutz, Julian, Dregan, Alexandru
    Publicado 2022
    “…RESULTS: Analyses included up to 297,380 middle-aged and older adults with a median follow-up of 12.19 (IQR = 1.31) years, yielding 3,516,706 person-years of follow-up. …”
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    Frailty in Individuals With Mental Disorders: Longitudinal Analyses of All-Cause Mortality
  14. 11254
    “…AIM: The aim of this study was to investigate malocclusion severity and its associations with oral health-related quality of life (OHRQoL) among middle-aged adults. MATERIALS AND METHODS: The study material consisted of 1786 subjects from the Northern Finland Birth Cohort 1966 who attended dental and oral examination as part of the 46-year-old follow-up study. …”
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    Malocclusion severity and its associations with oral health-related quality of life in an adult population
  15. 11255
    “…We first studied the expression of metabolic signature genes in gastrocnemius muscle of young, middle-aged and old mice. Then, old GHS-R knockout (Ghsr(−/−)) mice and their wild type counterparts were used to assess the impact of GHS-R ablation on the metabolic characteristics of gastrocnemius and soleus muscle. …”
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    Ablation of Ghrelin Receptor Mitigates the Metabolic Decline of Aging Skeletal Muscle
  16. 11256
    “…CASE PRESENTATION: We present a middle-age male with complaints of pain in the right lower quadrant of the abdomen with high grade fever for one week. …”
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    Pyelonephritis of an ectopic right kidney pretending as acute appendicitis: An unusual case
  17. 11257
    “…FMD occurs predominantly in early middle-age women, a fraction of the population where cardiovascular risk is different and understudied. …”
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    The complex genetic basis of fibromuscular dysplasia, a systemic arteriopathy associated with multiple forms of cardiovascular disease
  18. 11258
    “…CONCLUSIONS: Elevated urinary cotinine levels were associated with poor sleep quality in relatively young and middle-aged South Korean adults. Higher odds for poor sleep quality among cotinine-verified smokers who self-reported as never smokers also demonstrate the value of quantitative measurement of urinary cotinine. …”
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    The association between cotinine-measured smoking intensity and sleep quality
  19. 11259
    por Erdogdu, Suleyman
    Publicado 2022
    “…As a result, the risk of life-threatening coronary heart disease increases, as the majority of patients with tinnitus are in the middle age group and have high lipoprotein values. CONCLUSION: In patients presenting with the complaint of tinnitus, high serum lipoprotein values may not be directly related to tinnitus. …”
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    The frequency of dyslipidemia in patients with idiopathic tinnitus
  20. 11260
    “…Young service workers viewed themselves as being more vulnerable to risk of infection but less susceptible to getting severe disease, whilst exhibiting low levels of vaccine knowledge. Middle-aged (40–59 years) workers in the manufacturing industry underestimated both vulnerability to infection and disease severity, as well as demonstrated low knowledge of vaccines and practice of preventive measures. …”
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    Occupational disparities in COVID-19 vaccine hesitancy in Japan
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