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  1. 11321
    “…Latent class analysis of 1659 patients revealed the following patient groups: (1) young, high-needs males early in their disease course; (2) actively managed middle-aged patients; (3) elderly patients with multiple chronic conditions and polypharmacy; (4) unstably housed males with low treatment rates; (5) unstably housed females with high acute care use and low treatment rates. …”
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    Identifying Unique Subgroups of High-Cost Patients With Schizophrenia: A Population-Based Study Using Latent Class Analysis
  2. 11322
    por Lee, Mi-Sun, Lee, Hooyeon
    Publicado 2023
    “…Monitoring the risk factors of depressive symptoms, including OSA, or unhealthy behaviors may decrease the mental health issues of middle-aged and older adults.…”
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    The risk of obstructive sleep apnea is highly correlated with depressive symptoms among the Korean adults population: results from the 2020 Korea National Health and Nutrition Examination Survey
  3. 11323
    “…The prevalence of the disease in the overall sample was 79%, more prevalent in males in any age group and more frequent in the middle age group. The analyzes revealed that STOP-Bang performed better, both for the overall sample and for all age groups, followed by Berlin Questionnaire and Epworth Sleepiness Scale. …”
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    Obstructive sleep apnea screening in different age groups: performance of the Berlin, STOP-Bang questionnaires and Epworth Sleepiness Scale
  4. 11324
    “…Hyperthyroidism is considered the most common endocrinopathy in middle-aged and old cats. The increased level of thyroid hormones influences many organs, including the heart. …”
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    Comparative cardiac macroscopic and microscopic study in cats with hyperthyroidism vs. cats with hypertrophic cardiomyopathy
  5. 11325
    “…This study uses artificial intelligence for testing (1) whether the comorbidity of diabetes and its comorbid condition is very strong in the middle-aged or old (hypothesis 1) and (2) whether major determinants of the comorbidity are similar for different pairs of diabetes and its comorbid condition (hypothesis 2). …”
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    Explainable artificial intelligence on life satisfaction, diabetes mellitus and its comorbid condition
  6. 11326
    “…Microfracture, debridement and autologous chondrocyte implantation are not considered to be highly affected by age > 40 years by any of the respondents (0–3%). Moreover, for the middle-aged there is a large spread in treatments considered. …”
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    Cartilage repair strategies in the knee according to Dutch Orthopedic Surgeons: a survey study
  7. 11327
    por Ren, Tingting, Liu, Rui, Li, Jing, Ma, Jianmin
    Publicado 2023
    “…Both MD and SS are more common in middle-aged female, and the dry eyes could be presented in both of them with different degree. …”
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    Primary Sjögren’s syndrome misdiagnosed as Mikulicz’s disease: a case report
  8. 11328
    “…CASE REPORT: We present four different cases, all middle aged males, who sustained injuries due to crush, low velocity gun shot, and defects post-debridement of acute onset infections following abrasions. …”
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    Management of Soft-tissue Defects of Hand in a Conflict Combat Zone: A Case Series
  9. 11329
    “…CONCLUSION: The presence, extension, and progression of subclinical atherosclerosis in middle-aged asymptomatic individuals are associated with an acceleration in the Grim epigenetic age. …”
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    Subclinical atherosclerosis and accelerated epigenetic age mediated by inflammation: a multi-omics study
  10. 11330
    “…Using multiple mouse models, we explored the impact of aging on the size and severity of atherosclerotic lesions. In young, middle-aged and old apolipoprotein E knockout mice (ApoE(−/−)) fed an atherogenic diet (AD) for 3–8 weeks, plaque/atheroma formation in the descending aorta and aortic root, and atheroma development in the carotid in response to partial carotid ligation (PCL) were assessed. …”
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    Advancing age increases the size and severity of spontaneous atheromas in mouse models of atherosclerosis
  11. 11331
    “…BACKGROUD: The influencing factors of osteoporosis are complex, the incidence of osteoporosis is higher in middle-aged and elderly women, and osteoporotic fractures (OF) can seriously affect quality of life. …”
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    Gastrointestinal disease is an important influencing factor of osteoporosis fracture:a retrospective study in chinese postmenopausal women
  12. 11332
    “…Eighteen healthy young men (mean age [SD]: 22.7 years [3.1]) and seven middle‐aged to older individuals with OSA (54.4 years [6.4]) consumed a high‐fat meal during normoxia or intermittent hypoxemia (~15 hypoxic cycles per hour, ~85% oxyhemoglobin saturation) for 6 h. …”
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    No impact of a high‐fat meal coupled with intermittent hypoxemia on acute kidney injury biomarkers in adults with and without obstructive sleep apnea
  13. 11333
    “…BACKGROUND: Pulmonary sclerosing pneumocytoma (PSP) is a rare benign lung tumor which generally presents as a solitary pulmonary nodule in middle-aged females. However, the PSP in some patients exhibits potentially malignant biological behavior, with recurrence and lymphatic or distant metastasis being observed. …”
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    Giant pulmonary sclerosing pneumocytoma with potentially malignant biological behavior: a case report and literature review
  14. 11334
    “…Most research on psychological treatments to improve sleep has been conducted with middle-aged and older adults, which means it is unclear whether existing psychological treatments are helpful for young adult university students. …”
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    Preferences of University Students for a Psychological Intervention Designed to Improve Sleep: Focus Group Study
  15. 11335
    “…In both contrast-enhancing and non-enhancing tumors, age of 50 years or older was also significantly associated with GBM. CONCLUSION: In middle-aged and older patients with a mesial temporal lobe tumor, GBM is the most likely diagnosis even when there is no MRI contrast enhancement. …”
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    Clinical, radiological and pathological features of temporomesial tumors in the adult. A single center experience from 15 years
  16. 11336
    “…A total of 23.5% of the sample reported sleep difficulties (SDS ≥ 8) at a severity warranting follow-up with a trained sleep provider. Middle-aged adults generally reported significantly worse sleep health characteristics, relative to young adults, except young adults reported significantly longer sleep onset latency (SOL). …”
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    Sleep Health, Individual Characteristics, Lifestyle Factors, and Marathon Completion Time in Marathon Runners: A Retrospective Investigation of the 2016 London Marathon
  17. 11337
    “…The incidence gradually increased until middle age, followed by a decrease. The highest incidence rates were observed in the fifth decade of life for females and the sixth decade of life for males. …”
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    The current status of fibromyalgia in Korea: an electronic population health data study in Korea
  18. 11338
    “…Memory function declines in normal aging, in a relatively continuous fashion following middle-age. The effect of aging on decision-making is less well-understood, with seemingly conflicting results on both the nature and direction of these age effects. …”
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    Memory precision and age differentially predict the use of decision-making strategies across the lifespan
  19. 11339
    “…Multivariable logistic regressions were assessed for older adults (OA ≥65 years) when compared to young (YA, 18–39 years) and middle-aged adults (40–64 years). We found that the OA had features associated with a less complicated TB (e.g., lower prevalence of extra-pulmonary TB and less likely to abandon treatment or have drug resistant TB), and yet, were more likely to die during TB treatment (adj-OR 3.9, 95% 2.5, 5.25). …”
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    Tuberculosis presentation and outcomes in older Hispanic adults from Tamaulipas, Mexico
  20. 11340
    “…We employed a cross-correlation analysis on hand and head kinematics data collected from 122 healthy participants (ages: 20–90 years; divided as follows: young, middle-aged, and older adults) who completed the VR-CTT. …”
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    Higher cognitive load interferes with head-hand coordination: virtual reality-based study
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