“…Our results also suggest that the negative impact of the COVID-19 outbreak on psychological well-being is significantly greater for men, young adults, middle-aged adults, self-employed workers, and middle-income individuals. …”
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“…BACKGROUND: Osteonecrosis of the femoral head (ONFH) involves young or middle-aged adults, and its incidence is increasing along with increasing use of steroids in the management of organ transplantation and adjuvant therapy for malignant neoplasms. …”
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“…Male C57BL/6NCrl calorie restricted and ad libitum fed control mice were obtained from the National Institute on Aging (NIA) and studied at 10, 18, 26, and 28 months of age to better understand the metabolic changes that occur in response to CR in middle age and advanced age. Food intake was measured in ad libitum fed controls to assess the true degree of CR (15%) in these mice. …”
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“…In this prospective, randomized-controlled, and single-blind study, we administered an 8-week n-back training to 55 healthy middle-aged (50–64 years) participants. State-of-the-art multimodal neuroimaging was used to examine potential anatomic and functional changes. …”
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“…METHODS: Using data from the pairfam COVID-19 survey, an online survey of the participants of the German Family Panel pairfam conducted from May to July 2020, as well as personality data from the pairfam panel data, this study analyzes whether the Big Five personality traits influence the degree to which young and middle-aged individuals (16–49 years old) felt negatively affected by and were able to see any benefits of the initial COVID-19 lockdown in Germany. …”
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“…Ischemic heart disease (IHD) is a high-risk disease in the middle-aged and elderly population. The ischemic heart may be further damaged after reperfusion therapy with percutaneous coronary intervention (PCI) and other methods, namely, myocardial ischemia–reperfusion injury (MIRI), which further affects revascularization and hinders patient rehabilitation. …”
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“…One hundred eighty-nine participants (aged 50-87) were divided into three groups according to their age: middle-aged (MA; < 65), young older adults (YOA; 65-74), and old older adults (OOA; ≥75). …”
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“…Cluster 4 recipients were middle-aged, had diabetes or hypertension and received well-matched standard KDPI kidneys. …”
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“…We conducted a case–control study in elderly (≥65 years old; ELD) vs. younger adults (young/middle-aged adults (18–44/45–64 years old; YA|MAA) stratified by TB and T2D, using a research study population (n = 1160) and TB surveillance data (n = 8783). …”
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“…METHODS AND RESULTS: Twenty healthy middle‐aged men consume CF (bi‐daily 450 mg) or control drinks for 1 month. …”
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“…The recruited patients were mainly young and middle-aged, with more males than females. There were no significant differences in smoking history, comorbidities and opportunistic infections between the two groups. …”
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“…It was observed that adherence was improved on middle age. Treatment adherence was found to be higher in patients receiving medication due to disorders other than hepatitis B. …”
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“…In 18 studies (78%), patients were children, in five (22%), young or middle-aged adults. No study included elderly or frail patients. …”
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“…CONCLUSION: Our study shows that middle-aged female patients may be more difficult to satisfy. …”
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“…CONCLUSION: Based on the results, depression is highly prevalent in Saudi patients with RA, especially those with positive RF and those who are female, middle-aged, and divorced. Early detection and treatment of depression in patients with RA is highly recommended to improve their quality of life and avoid unfavorable effects on RA clinical progression.…”
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“…Promoting breastfeeding may reduce the burden of peripheral neuropathy in middle-aged postmenopausal women.…”
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“…Moreover, genes associated with oxidoreductase activity and oxidation–reduction process were hypermethylated in Tet2-deficient oocytes from middle-age mice treated with resveratrol, indicating that loss of Tet2 abolishes the antioxidant effect of resveratrol. …”
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“…DISCUSSION: SOVA is a rare finding but should still be considered in the differential in young and middle-aged patients with symptoms of acute heart failure, hemodynamic compromise, and a new continuous heart murmur. …”
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“…The percentage of those with PD was higher among younger and middle-aged (< 61 years old) than older (> 61 years old) adults. …”
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“…RESULTS: A total of 14,222,326 (21%) of all inpatient cases aged ≥ 40 years had a diagnosis of diabetes. More middle-aged females with vs. without diabetes/100,000 individuals [95% CI] were observed, most pronounced in cases aged 40–< 50 years with myocardial infarction (305 [293–319] vs. 36 [36–37], p < 0.001). …”
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