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  1. 11821
    “…CONCLUSIONS: COPD is highly prevalent among medically complex middle‐aged and older nursing home residents with heart failure. …”
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    Differences in chronic obstructive pulmonary disease among US nursing home residents with heart failure according to sex and type of heart failure
  2. 11822
    “…Preventive and rehabilitative programs should be implemented that firstly target middle-aged females and males.…”
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    The burden of neck pain in the Middle East and North Africa region, 1990–2019
  3. 11823
    “…Previous studies showed the beneficial effects on cognitive functions in middle-aged adults. However, it is unclear that 6-MSITC has a positive effect on cognitive functions in healthy older adults aged 60 years and over. …”
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    Benefits of Wasabi Supplements with 6-MSITC (6-Methylsulfinyl Hexyl Isothiocyanate) on Memory Functioning in Healthy Adults Aged 60 Years and Older: Evidence from a Double-Blinded Randomized Controlled Trial
  4. 11824
    “…However, the migration of a large number of young and middle-aged rural laborers has undermined the traditional arrangements for old-age care in rural areas and affected the psychological health of the older adult. …”
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    The impact of adult children’s support on the psychological health of rural older adult people in China
  5. 11825
    “…Arterial stiffness, an independent predictor of CVDs, is particularly elevated in both conditions, yet the molecular mechanisms underlying this phenomenon remain elusive, hindering effective management of CVDs in this population. We recruited 20 middle-aged Emiratis, including 9 individuals with vitamin D deficiency (Vit D level ≤20 ng) and obesity (BMI ≥30) and 11 individuals as control with Vit D level >20 ng and BMI <30. …”
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    Unveiling the molecular Culprit of arterial stiffness in vitamin D deficiency and obesity: Potential for novel therapeutic targets
  6. 11826
    “…Comparing the bottom versus top third of serum testosterone, the corresponding (adjusted) risk estimates were 1.76 (1.11–2.81) and 1.76 (1.10–2.80), respectively. In middle-aged and older Finnish men, elevated levels of serum testosterone were associated with an increased risk of AS. …”
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    Association between Serum Testosterone and Aortic Valve Stenosis: A Prospective Cohort Study
  7. 11827
    “…This disease generally occurs in middle-aged and older adults, but there are also reports of it occurring in young people. …”
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    Vasospastic Angina in a Young Woman: A Case Report
  8. 11828
    “…METHODS: The association between the parameters of skeletal muscle and RPV/body surface area (BSA) was analyzed by computed tomography in 728 middle-aged participants without kidney disease or diabetes mellitus in a cross-sectional study. …”
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    Trunk muscle quality and quantity are associated with renal volume in nondiabetic people
  9. 11829
    “…More severe inflammation contained more plasma cells, and more dense giant cells were seen in middle aged patients.…”
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    Clinicopathologic evaluation of granuloma annulare: Study of 136 Iranian cases, south of Iran
  10. 11830
    “…Apolipoprotein E (ApoE) genotype, the major genetic risk factor in sporadic late-onset Alzheimer Disease (AD), modulates cerebral perfusion in late middle-age cognitively normal subjects. ApoE ε4 homozygous have reduced glucose metabolism in the same regions involved in AD. …”
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    Functional correlates of Apolipoprotein E genotype in Frontotemporal Lobar Degeneration
  11. 11831
    “…METHODS: We conducted a cross-sectional survey with 418 members of the general middle-aged and senior adults (aged between 40 and 65) in Tokyo, Japan. …”
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    Survey of the general public's attitudes toward advance directives in Japan: How to respect patients' preferences
  12. 11832
    “…Respondents were predominantly middle-aged Caucasian females, most of whom had FM symptoms for ≥ 4 years. …”
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    An internet survey of 2,596 people with fibromyalgia
  13. 11833
    “…METHODS: We conducted a prospective investigation of the relation between usual intake of choline and betaine with the risk of CHD in 14,430 middle-aged men and women of the biethnic Atherosclerosis Risk in Communities study. …”
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    Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study
  14. 11834
    “…The healing rates of damaged endothelia for young, middle-aged, and old persons are compared and are found to be particularly sensitive to the stem cell homing parameter. …”
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    A continuum mathematical model of endothelial layer maintenance and senescence
  15. 11835
    “…Many middle-aged patients are affected by localized cartilage defects that are neither appropriate for primary, nor repeat biological repair methods, nor for conventional arthroplasty. …”
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    Effects of a contoured articular prosthetic device on tibiofemoral peak contact pressure: a biomechanical study
  16. 11836
    “…BACKGROUND: This cross-sectional study of two middle-aged community samples from Sweden and Russia examined the distribution of perceived control scores in the two populations, investigated differences in individual control items between the populations, and assessed the association between perceived control and self-rated health. …”
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    Adverse health effects of low levels of perceived control in Swedish and Russian community samples
  17. 11837
    “…In the obese group, a history of falls was related (p ≤ 0.05) to lower scores in 4 domains of HRQL, and ambulatory stumbling was related (p ≤ 0.01) to 7 domains. CONCLUSION: In middle-aged and older adults, obesity was associated with a higher prevalence of falls and stumbling during ambulation, as well as lower values in multiple domains of HRQL. …”
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    The influence of obesity on falls and quality of life
  18. 11838
    “…This study aimed to describe the use of these drugs among middle-aged Finnish coronary patients and to identify patient groups in risk of being prescribed inadequate medication for secondary prevention of coronary heart disease. …”
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    Equity in the use of antithrombotic drugs, beta-blockers and statins among Finnish coronary patients
  19. 11839
    “…CONCLUSION: In men in this cohort, exposure to disadvantaged social circumstances across the lifecourse, but particularly in adulthood, is associated with detrimental patterns of alcohol consumption and problem drinking in late middle age.…”
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    Problem drinking and exceeding guidelines for 'sensible' alcohol consumption in Scottish men: associations with life course socioeconomic disadvantage in a population-based cohort study
  20. 11840
    “…Most of these referred patients were over-weight middle-aged men with elevated ferritin levels, but without the hemochromatosis-predisposing gene mutations. …”
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    Hyperferritinemia Is Associated with Insulin Resistance and Fatty Liver in Patients without Iron Overload
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