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  1. 11901
    “…Mets was significantly related to age, sex and education. Middle-aged and elderly smokers were at approximately 4-5 times higher risk among Mets subjects. …”
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    Socioeconomic Disparities and Smoking Habits in Metabolic Syndrome: Evidence from Isfahan Healthy Heart Program
  2. 11902
    “…CONCLUSION: In a young to middle aged and relatively healthy Caucasian population, MBL2 variants related to functional MBL deficiency were associated with a doubling of the risk for MI, independent of conventional risk factors. …”
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    Mannose-Binding Lectin Deficiency Is Associated with Myocardial Infarction: The HUNT2 Study in Norway
  3. 11903
    “…BACKGROUND: This study aimed to compare Iranian elderly with the middle-aged population in terms of the prevalence of metabolic syndrome and its components. …”
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    Metabolic syndrome in Iranian elderly
  4. 11904
    “…METHODS: Approximately 1.3 million middle-aged women were recruited in the United Kingdom during 1996–2001 and followed for death, emigration and cancer registration until 2009 (mean 10.3 years per woman); potential risk factors were assessed by questionnaire. …”
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    Alcohol drinking, tobacco smoking and subtypes of haematological malignancy in the UK Million Women Study
  5. 11905
    “…We measured intensity thresholds for pure-tone detection and pure-tone loudness discrimination in a population of healthy adults and a middle-aged man with complete or near-complete lesions of the auditory cortex bilaterally. …”
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    Dissociation of Detection and Discrimination of Pure Tones following Bilateral Lesions of Auditory Cortex
  6. 11906
    “…Both 12 weeks- (young) and 1 year-PTU (middle age) treatment caused a remarkable capillary rarefaction observed in capillary density. …”
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    Thyroid hormone induces sprouting angiogenesis in adult heart of hypothyroid mice through the PDGF-Akt pathway
  7. 11907
    “…CONCLUSIONS: VFA ⩾80 cm(2) effectively identified carotid atherosclerosis for both lean and obese individuals in middle-aged Chinese men.…”
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    Contribution of visceral fat accumulation to carotid intima–media thickness in a Chinese population
  8. 11908
    “…RESULTS: A total of 302 subjects were enrolled and the majority of these were young to middle-aged women (45.8 ±18.5 years); only one third of them were treated by rheumatologists. …”
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    Characteristics of comorbidities and costs among patients who died from systemic lupus erythematosus in Taiwan
  9. 11909
    “…We present a case of unusual primary HL in rib occurring in a middle-aged female patient. Computed tomography (CT) scan revealed an osteolytic lesion was located at the right second rib and was associated with a large soft tissue mass. …”
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    Unusual primary osseous Hodgkin lymphoma in rib with associated soft tissue mass: a case report and review of literature
  10. 11910
    por Sun, Ping, Juskevicius, Ridas
    Publicado 2012
    “…Persistent polyclonal B-cell lymphocytosis (PPBL) is rare and intriguing hematological disorder predominantly reported in young to middle- aged smoking women. It is characterized by persistent moderate polyclonal B-cell lymphocytosis with circulating hallmark binucleated lymphocytes and elevated polyclonal serum IgM. …”
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    Histological and immunohistochemical features of the spleen in persistent polyclonal B-cell lymphocytosis closely mimic splenic B-cell lymphoma
  11. 11911
    “…RESULTS: Subjects were divided into early (age at AR below 5.4 years of age), middle (age at AR 5.4 to 6.8 years of age) and late (age at AR after 6.8 years of age) age at AR tertiles. …”
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    Age at Adiposity Rebound Is Associated with Fat Mass in Young Adult Males—The GOOD Study
  12. 11912
    “…CONCLUSIONS: This study demonstrates that British women who had previously undergone hysterectomy had higher BMI and waist circumference in middle-age than others. These differences appear to be accounted for by the higher BMI in earlier adulthood and increased levels of risk factors associated with both adiposity and hysterectomy risk among women who had undergone hysterectomy. …”
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    Is there an association between hysterectomy and subsequent adiposity?
  13. 11913
    “…CONCLUSION: Bothersome neck pain is most common in middle-aged individuals. Women are more likely than men to have and to develop bothersome neck pain, and less likely to recover from such pain. …”
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    The age- and sex-specific occurrence of bothersome neck pain in the general population – results from the Stockholm public health cohort
  14. 11914
    “…We aimed to assess the association between central obesity and prevalence and incidence of albuminuria in a middle-aged population-based cohort study. METHODS: This is a cross-sectional and longitudinal cohort study. …”
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    Central Obesity and Albuminuria: Both Cross-Sectional and Longitudinal Studies in Chinese
  15. 11915
    “…The cohort was stratified into young (<40 yrs), middle-aged (41–59 yrs) and aged (>60 yrs) groups. In the aged cohort, the CD8+ T cell compartment displayed a marked reduction in the frequency of naïve CD8+ T cells and increased frequencies of CD8+ T cells that expressed CD57 and lacked CD28, as previously described. …”
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    The Polyfunctionality of Human Memory CD8+ T Cells Elicited by Acute and Chronic Virus Infections Is Not Influenced by Age
  16. 11916
    “…BACKGROUND: Multiple sclerosis (MS) is a disease of young and middle aged individuals with a demyelinative axonal damage nature in central nervous system that causes various signs and symptoms. …”
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    Color blindness among multiple sclerosis patients in Isfahan
  17. 11917
    “…Our study, the first of its kind in Cameroon, analyzed the distribution and antibiotic susceptibility of bacteria causing community-acquired urinary tract infection (CAUTI) in two towns (Bamenda and Buea) with a large number of young and middle aged persons, to provide data that could guide empiric treatment. …”
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    Etiologic profile and antimicrobial susceptibility of community-acquired urinary tract infection in two Cameroonian towns
  18. 11918
    “…To better understand radiation-induced normal tissue injury and how it may be affected by aging, we exposed young adult, middle-aged, and old rats to 10 Gy of whole brain irradiation and assessed in gray- and white matter the responses of microglia, the primary cellular mediators of radiation-induced neuroinflammation, and oligodendrocyte precursor cells, the largest population of proliferating cells in the adult brain. …”
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    Regionally Distinct Responses of Microglia and Glial Progenitor Cells to Whole Brain Irradiation in Adult and Aging Rats
  19. 11919
    “…The formation and maintenance of social relationships in youth and middle age are important components of human mental health. …”
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    The Roles of Oxytocin and CD38 in Social or Parental Behaviors
  20. 11920
    “…Neuronal AR deficiency leads to reduced insulin sensitivity in middle-aged mice. Neuronal AR regulates hypothalamic insulin signaling by repressing nuclear factor-κB (NF-κB)–mediated induction of protein-tyrosine phosphatase 1B (PTP1B). …”
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    Neuronal Androgen Receptor Regulates Insulin Sensitivity via Suppression of Hypothalamic NF-κB–Mediated PTP1B Expression
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