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  1. 1221
    “…OBJECTIVES: This paper investigates (1) how social relationships (SRs) relate to the frequency of general practitioner (GP) visits among middle-aged and older adults in Europe, (2) if SRs moderate the association between self-rated health and GP visits, and (3) how the associations vary regarding employment status. …”
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    Social relationships and GP use of middle-aged and older adults in Europe: a moderator analysis
  2. 1222
    “…The prevalence of cardiovascular disease has increased among middle-aged women in the United States, yet has declined in middle-aged men. …”
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    Sex Differences in Adipose Tissue CD8(+) T Cells and Regulatory T Cells in Middle-Aged Mice
  3. 1223
    “…We assessed 35 non-demented middle-aged and older adults (25 women, 10 men; 45–75 years) using the International Physical Activity Questionnaire for older adults, which quantifies physical activity levels in MET-equivalent units and asks about the average number of hours spent sitting per day. …”
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    Sedentary behavior associated with reduced medial temporal lobe thickness in middle-aged and older adults
  4. 1224
    por Cha, Seung-Eun, Eun, Ki-Soo
    Publicado 2018
    “…Although the gender gap in sleep time has narrowed significantly in the last decade, middle-aged women between ages 35 and 60 still sleep less than their male counterparts in Korea. …”
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    Convergence in Sleep Time Accomplished? Gender Gap in Sleep Time for Middle-Aged Adults in Korea
  5. 1225
    “…BACKGROUND: The ε4 allele of the apolipoprotein E gene (APOE-ε4) is the strongest genetic factor for late-onset Alzheimer’s disease. During middle age, cognitively healthy APOE-ε4 carriers already show several brain alterations that resemble those of Alzheimer's disease (AD), but to a subtler degree. …”
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    White matter microstructure is altered in cognitively normal middle-aged APOE-ε4 homozygotes
  6. 1226
    “…In conclusion, after 12 weeks of taking 5-ALA, we found significant improvements in self-perception of effort spent, loneliness, and coping ability in prediabetic middle age and older adults. Improved mood and coping ability may allow prediabetic individuals to overcome the emotional obstacles preventing them from maintaining a healthy lifestyle and ultimately, help them to avoid the development of diabetes.…”
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    The Relationship of 5-Aminolevulinic Acid on Mood and Coping Ability in Prediabetic Middle Aged and Older Adults
  7. 1227
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    Drug-induced Pressure Ulcers in a Middle-aged Patient with Early-stage Parkinson's Disease
  8. 1228
    “…OBJECTIVES: Hospitalisations for serious infections are common among middle age and older adults and frequently used as study outcomes. …”
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    Validation of discharge diagnosis codes to identify serious infections among middle age and older adults
  9. 1229
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    Habitual hot water bathing protects cardiovascular function in middle-aged to elderly Japanese subjects
  10. 1230
    “…Effective improvement of hippocampal neurogenesis was also caused by intermittent voluntary wheel running in middle-aged mice.…”
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    Effects of Voluntary Wheel-Running Types on Hippocampal Neurogenesis and Spatial Cognition in Middle-Aged Mice
  11. 1231
    “…It is an uncommon but life-threatening case of infective endocarditis in middle-aged otherwise healthy adults. We present a case of a patient with life-threatening infective endocaritis caused by Streptococcus agalactiae, who passed away despite medical treatment.…”
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    Streptococcus Agalactiae Infective Endocarditis in a Healthy Middle-aged Man: Uncommon but Life-threatening
  12. 1232
    por Ouyang, Peng, Sun, Wenjun
    Publicado 2018
    “…Individuals were divided into subgroups according to gender (male or female), age (45–59, middle-aged or ≥ 60, elderly people), and residence (rural or urban). …”
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    The association between depressive symptoms and fall accidents among middle-aged and elderly people in China
  13. 1233
    “…Clinical efficacy of meniscal plasty and total meniscectomy under arthroscopy in treating middle-aged and elderly patients with meniscus injury were explored. …”
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    Clinical efficacy of meniscus plasty under arthroscopy in middle-aged and elderly patients with meniscus injury
  14. 1234
    “…BACKGROUND: The principal aim of this study was to demonstrate the gender-specific cognitive patterns among middle-aged and elderly Chinese adults, investigate the risk factors on global and domain-specific cognitive performance in men and women, respectively, and report demographically adjusted norms for cognitive tests. …”
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    Patterns of cognitive function in middle-aged and elderly Chinese adults—findings from the EMCOA study
  15. 1235
    “…RESULTS: Middle-aged non-problematised drinkers constructed their drinking practices by creating a narrative of normative drinking via discourses of gender, identity, play, and learning to drink. …”
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    Constructions of alcohol consumption by non-problematised middle-aged drinkers: a qualitative systematic review
  16. 1236
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    Neuroprotective Effects of the Multitarget Agent AVCRI104P3 in Brain of Middle-Aged Mice
  17. 1237
    “…PURPOSE: The aim of the present study was to assess the effect of prolonged and repeated exercise on iron metabolism in middle-aged adults and to compare differences between sexes. …”
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    Changes in iron metabolism during prolonged repeated walking exercise in middle-aged men and women
  18. 1238
    “…Results revealed a significant methylation change acceleration in middle-aged males (40–50 years old), which was further supported by another cohort containing 2711 subjects with Indian ancestry. …”
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    Accelerated DNA methylation changes in middle-aged men define sexual dimorphism in human lifespans
  19. 1239
    por Hwang, Jongnam, Park, Sangmin, Kim, Sujin
    Publicado 2018
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    Effects of Participation in Social Activities on Cognitive Function Among Middle-Aged and Older Adults in Korea
  20. 1240
    por Bu, Estella Qian Lin, Chung, Ho Jin
    Publicado 2018
    “…Despite the initiatives, the obesity rate in middle-aged women is still high. This study seeks to understand and identify the vast barriers that prevent middle-aged women from exercising. …”
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    Barriers towards exercise and physical activity of different ethnic groups in middle-aged female Singaporeans
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