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  1. 12821
    “…Moreover, FPDs were significantly the highest restorations among young-adult and middle-aged patients (P-value = 0.00). CONCLUSION: There was a clear change in prosthetic rehabilitation trends over the past few years. …”
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    Changing trends of prosthetic rehabilitation of partially edentulous patients visiting a tertiary care dental hospital
  2. 12822
    “…Patients were mostly middle-aged, males, whites, and had significant comorbidities. …”
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    Endobronchial valves for persistent air leak all-cause mortality and financial impact: US trend from 2012–2016
  3. 12823
    “…It is necessary to inform patients to focus more on medical institutions that provide primary care, adjust the proportion of medical insurance reimbursement, control the cost of hospitalization and strengthen the healthcare management of middle-aged and elderly diabetic patients. Only in this way can costs be reduced and the economic burden be eased.…”
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    How Serious is the Economic Burden of Diabetes Mellitus in Hainan Province? A Study Based on “System of Health Account 2011”
  4. 12824
    “…METHODS AND ANALYSES: We will conduct a systematic review to evaluate vitamin D and calcium recommendations for osteoporosis prevention in generally healthy middle-aged and older adults. Methodological assessment will be performed for each guideline against those outlined in the 2014 WHO handbook for guideline development. …”
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    Methodological quality of public health guideline recommendations on vitamin D and calcium : a systematic review protocol
  5. 12825
    “…CONCLUSION: Pulmonary LELC looks like distinct from squamous carcinoma. Middle-aged women and nonsmokers are comparatively predominated. …”
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    Primary pulmonary lymphoepithelioma-like carcinoma: a rare type of lung cancer with a favorable outcome in comparison to squamous carcinoma
  6. 12826
    “…Average APC among men aged ≥75 years did not decrease. Among middle-aged and older women (75–84 and ≥85 years) decreasing trends were observed. …”
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    Fall-related mortality trends in older Japanese adults aged ≥65 years: a nationwide observational study
  7. 12827
    “…CONCLUSIONS: A small reduction in mortality may be achieved by sustained elevated physical activity levels in healthy middle-aged adults, but there may be comparatively little gain from increasing adherence to a Mediterranean-style diet.…”
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    Sustained adherence to a Mediterranean diet and physical activity on all-cause mortality in the Melbourne Collaborative Cohort Study: application of the g-formula
  8. 12828
    “…Conclusions: We concluded that middle-aged men accounted for most of the patients with chronic hepatitis B in this cross-sectional study. …”
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    Baseline Characteristics and Treatment Patterns of the Patients Recruited to the China Registry of Hepatitis B
  9. 12829
    “…Prevalence of obesity increased with age until late middle age and then declined; increased only slightly across surveys; but increased steadily with birth year until the 1960s and then accelerated. …”
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    Flexible age-period-cohort modelling illustrated using obesity prevalence data
  10. 12830
    “…The objective of this study was to investigate the relation between dairy product consumption and the risk of hypertension among middle-aged women. METHODS: In a prospective cohort of 40,526 French women, there were 9340 new cases of hypertension after an average 12.2 years of follow up. …”
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    Dairy product consumption and hypertension risk in a prospective French cohort of women
  11. 12831
    “…Within these municipalities, a random sample of men and women between 18 and 75 years of age was selected and invited to participate. In total, 562 middle-aged Belgian adults were tested in 2002 and 2012 for the same anthropometric, lifestyle, nutrition and physical activity parameters. …”
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    Assessment of sugar-sweetened beverage consumption and weight change: a prospective cohort study
  12. 12832
    por Wruck, Wasco, Adjaye, James
    Publicado 2020
    “…In sex-specific analysis we identified genes correlating with age and differentially expressed between groups of young, middle-aged and aged. Pathways and gene ontologies (GOs) over-represented in the resulting gene sets were calculated. …”
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    Meta-analysis of human prefrontal cortex reveals activation of GFAP and decline of synaptic transmission in the aging brain
  13. 12833
    “…Multiple logistic regression showed that BMI recording was higher in females, the middle age bands, persons living in the most deprived areas and within persons who were hypertensive, had serious mental illness or were multimorbid. …”
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    Characteristics of patients with body mass index recorded within the Kent Integrated Dataset (KID)
  14. 12834
    “…We also observed that there was no difference in the prevalence of hepatitis B between males and females in areas where schistosomiasis was endemic (χ(2)=1.827, p=0.177), but the prevalence of hepatitis B in middle-aged people was higher than in other age groups (χ(2)=47.877, p<0.001). …”
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    Prevalence and co-infection of schistosomiasis/hepatitis B among rural populations in endemic areas in Hubei, China
  15. 12835
    “…This study aimed to identify genes associated with cognition in later life using integrated enrichment analyses of the results of blood-derived intra-pair epigenome-wide and transcriptome-wide association analyses of cognition in 452 middle-aged and old-aged monozygotic twins (56–80 years). …”
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    A Genome-Wide Integrative Association Study of DNA Methylation and Gene Expression Data and Later Life Cognitive Functioning in Monozygotic Twins
  16. 12836
    “…METHODS: Data were collected from the six-wave Korean Longitudinal Study of Ageing (2006–2016). A total of 9263 middle-aged and older adults were included in the analysis. …”
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    The impact of poverty transitions on frailty among older adults in South Korea: findings from the Korean longitudinal study of ageing
  17. 12837
    “…METHODS: A cross-sectional analysis was conducted using data on 747 middle-aged women obtained from the Study of Women’s Health Across the Nation (SWAN) from 1996 to 2008. …”
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    Is menopause still evolving? Evidence from a longitudinal study of multiethnic populations and its relevance to women’s health
  18. 12838
    “…Multiple vaginal delivery (MVD) is an important factor for pelvic floor muscle (PFM) function decline and pelvic floor dysfunction (PFD). PFD is common in middle-aged and elderly women, but its pathogenesis is not clear. …”
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    CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade
  19. 12839
    “…BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) increases the risk of hepatocellular carcinoma, which is currently the leading cause of obesity-related cancer deaths in middle-aged men. METHODS: Probiotics with lipid-lowering function were screened from the fecal microbiota of healthy adults. …”
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    Combination of Probiotics and Salvia miltiorrhiza Polysaccharide Alleviates Hepatic Steatosis via Gut Microbiota Modulation and Insulin Resistance Improvement in High Fat-Induced NAFLD Mice
  20. 12840
    “…METHODS: Using data from middle age to elderly individuals (age 55+ years) from two Danish cohorts of monozygotic twins and the Scottish Lothian Birth Cohort 1921, we conducted an X-chromosome-wide analysis of age-associated DNA methylation patterns with consideration of stably inferred XCI status. …”
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    Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples
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