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  1. 12861
    “…Avascular necrosis of femoral head (AVNFH) is a debilitating disease, which affects the middle aged population. Though the disease is managed using bisphosphonate, it eventually leads to total hip replacement due to collapse of femoral head. …”
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    Systems analysis of avascular necrosis of femoral head using integrative data analysis and literature mining delineates pathways associated with disease
  2. 12862
    “…METHODS: Twenty healthy, middle-aged to older males underwent brain DCE MRI. …”
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    Permeability of the windows of the brain: feasibility of dynamic contrast-enhanced MRI of the circumventricular organs
  3. 12863
    “…Clinical characteristics of the latter are heterogeneous and not yet fully elucidated, while the pathogenesis appears related to neuroinflammation in a subset of patients. Case: A middle-aged man presented with acute language disturbance at the emergency department. …”
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    Encephalopathy in COVID-19 Presenting With Acute Aphasia Mimicking Stroke
  4. 12864
    “…In the general population, females scored higher than males, and middle-aged and older adults scored higher than young adults. …”
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    Reliability and validity of a General Nutrition Knowledge Questionnaire for adults in a Romanian population
  5. 12865
    “…Prevalence was low in children less than ten years, highest in the middle age and getting lower in higher age (≥ 50 years). …”
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    Risk factors for respiratory Aspergillus fumigatus in German Cystic Fibrosis patients and impact on lung function
  6. 12866
    “…Here, 14-month-old male Sprague–Dawley (SD) rats were divided into a middle-aged control group (18-month-old control group), an old control group (28-month-old control group), and a long-term runner group (28-month-old runner group). …”
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    Long-Term Running Exercise Delays Age-Related Changes in White Matter in Rats
  7. 12867
    “…Brain surgery for the young, anxious status for the middle-aged, and depressive status for the elderly were risk factors for CI at different ages. …”
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    One-Year Analysis of Risk Factors Associated With Cognitive Impairment in Newly Diagnosed Epilepsy in Adults
  8. 12868
    “…METHODS: In this cross-sectional, retrospective, cohort study, the prevalence and incidence of DM was analyzed in 803 and 624 middle-aged Japanese participants, respectively. The cross-sectional area of the abdominal adipose tissue was evaluated from an unenhanced computed tomography scan at the third lumbar vertebrae, and the IVAT or RVAT was analyzed using specialized software. …”
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    Intraperitoneal, but not retroperitoneal, visceral adipose tissue is associated with diabetes mellitus: a cross-sectional, retrospective pilot analysis
  9. 12869
    “…Histopathological abnormalities can occur prior to the onset of fatty infiltration. In middle-aged controls, almost all biopsies showed some histopathological abnormalities. …”
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    Correlation Between Quantitative MRI and Muscle Histopathology in Muscle Biopsies from Healthy Controls and Patients with IBM, FSHD and OPMD
  10. 12870
    “…METHODS: A cross‐sectional study was conducted among 4365 middle‐aged adults. Major DPs and DII score were identified using a validated semi‐quantitative food frequency questionnaire (FFQ). …”
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    Dietary Inflammatory Index is associated with Healthy Eating Index, Alternative Healthy Eating Index, and dietary patterns among Iranian adults
  11. 12871
    “…Widespread immune cell activation is especially pronounced and first detectable in white adipose depots during middle age. Single-cell RNA-sequencing confirms the accumulation of adipose T and B cells, including immunoglobulin J-expressing plasma cells, which also accrue concurrently across diverse organs. …”
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    Aging hallmarks exhibit organ-specific temporal signatures
  12. 12872
    “…The effect of physical composite score on survival was prominent among young or middle-aged groups. CONCLUSION: Poor physical health status 3 months after hemodialysis start correlates significantly with overall mortality.…”
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    Impact of health-related quality of life on survival after dialysis initiation: a prospective cohort study in Korea
  13. 12873
    “…DISCUSSION: Our conceptual hypothesis is that beach tennis training will reduce ambulatory blood pressure and improve fitness parameters in middle-aged individuals with hypertension. The results of this trial are expected to provide evidences of efficacy of recreational beach tennis practice on blood pressure management and to support sport recommendations for clinical scenario in higher risk populations. …”
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    Effect of recreational beach tennis on ambulatory blood pressure and physical fitness in hypertensive individuals (BAH study): rationale and study protocol
  14. 12874
    “…BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common lung disease during middle age which one of its complications is depression. …”
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    The associations between dietary pattern of chronic obstructive pulmonary disease patients and depression: a cross-sectional study
  15. 12875
    “…The prevalence of diabetes and dyslipidemia were highest in middle age. A majority (76.9%) of the patients with AMI had at least 1 of these coronary risk factors. …”
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    In-hospital morality associated with acute myocardial infarction was inversely related with the number of coronary risk factors in patients from a Japanese nation-wide real-world database
  16. 12876
    “…Segment one is more likely to be younger and older high-income workers; whereas, segment two includes middle-aged lower-income, unemployed individuals. The model results suggest that daily activity engagement and sociodemographic attributes significantly affect travel satisfaction. …”
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    COVID-19: Are you satisfied with traveling during the pandemic?
  17. 12877
    “…We quantified absolute mtDNA-CN in both prevalent and incident T2DM by well-optimized droplet digital PCR (ddPCR) method in a population-based follow-up study of middle aged (50–59 years) Swedish women (n = 2387). …”
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    Association of mitochondrial DNA copy number with prevalent and incident type 2 diabetes in women: A population-based follow-up study
  18. 12878
    “…For age, young people are prioritized for ICU treatment, while the middle-aged are given priority over a vaccine, with younger respondents favoring healthcare for elderly claimants, while older respondents favor support for young cohorts. …”
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    The perceived deservingness of COVID-19 healthcare in the Netherlands: a conjoint experiment on priority access to intensive care and vaccination
  19. 12879
    “…BACKGROUND: Immunoglobulin G4-related disease (IgG4-RD) is a multi-organ disorder predominantly occurring in middle-aged to elderly male patients characterized by multi-organ fibrosis, specific pathological findings of storiform fibrosis with IgG4-positive plasma cell infiltration, and elevated serum IgG4 level. …”
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    Isolated middle mediastinal mass associated with immunoglobulin G4-related disease
  20. 12880
    “…METHODS: We enrolled 9960 middle-aged and elderly subjects (6726 women and 3234 men) and performed a 3-year follow-up cohort study. …”
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    Hemoglobin concentration is associated with the incidence of metabolic syndrome
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