“…BACKGROUND: Parkinson’s disease (PD) is the second most common neurodegenerative disease in middle-aged and elderly populations, whereas there is no cure for PD so far. …”
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“…RESULTS: The results showed that the most moderate stress levels were middle age (22.2%), women 33.3% had higher stress levels than men (10%), the highest vaccination coverage was 26.7% at a distance of 1–2 KM. …”
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“…CASE PRESENTATION: We present the case of a middle-aged man with anxiety disorder, AUD, chronic pain, and gamma-hydroxybutyrate use in context of tapering prescribed benzodiazepines who experienced severe alcohol withdrawal episodes during a complicated course of repeated inpatient withdrawal management. …”
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“…Diabetic retinopathy (DR) is a universal microvascular complication of diabetes mellitus (DM), which is the main reason for global sight damage/loss in middle-aged and/or older people. Current clinical analyses, like hemoglobin A1c, possess some importance as prognostic indicators for DR severity, but no effective circulating biomarkers are used for DR in the clinic currently, and studies on the latent pathophysiology remain lacking. …”
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“…Frailty prevalence estimates for this middle-aged, predominantly male, population varied between 2.7% and 100%. …”
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“…Our first case is that of a middle-age woman who presented with spontaneous tetany and perioral numbness. …”
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“…Patient: Female, 58-year-old Final Diagnosis: Giant bullae • spontaneous pneumothorax • subcutaneous emphysema Symptoms: Crepitus • dysphagia • dysphonia • facial swelling Medication: — Clinical Procedure: — Specialty: Critical Care Medicine • Pulmonology OBJECTIVE: Unusual clinical course BACKGROUND: Vanishing lung syndrome (VLS), also known as idiopathic giant bullous emphysema, is a rare manifestation of chronic obstructive pulmonary disease (COPD) and usually occurs in middle-aged smokers. This report presents a 58-year-old female smoker with COPD and VLS who presented with spontaneous pneumothorax. …”
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“…The absence of clear improvements in health emphasises the importance of current and future preventive measures to maintain health, especially among the middle-aged and older labour force. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10433-022-00707-0.…”
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“…We report a challenging case of a middle-aged woman with DHF complicated by acute liver failure, coagulopathy, acute renal failure and prolonged intrahepatic cholestasis. …”
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“…A case of SAPHO syndrome being reported in a middle-aged man who presented with bilateral PPP and exacerbation of back pain which developed shortly after covid-19 vaccine injection with a history of more than 20 years of inflammatory thoracic back pain and psoriasis vulgaris who initially had been worked up for metastatic bony lesions based on radiologic studies, irrespective of his skin lesions. …”
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“…The results suggest younger and older aged individuals experienced/perceived lower benefits and higher barriers to teleworking compared to middle aged individuals. The results also suggest a disproportionate impact on Hispanic or Latino and Black respondents as well as on those with children attending online school from home. …”
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“…However, our data indicate the following: Growth slowdown and regression are very common phenomena in the natural history of micro-PTC, clinical PTC in young and middle-aged patients, and hereditary MTC. The biologic characteristics of cancers of the same name, such as PTC, are diverse and vary widely with age. …”
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“…METHODS AND RESULTS: This randomized controlled trial was conducted among middle-aged subjects with a top 20% CAD PRS in a family medicine setting. …”
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“…CONCLUSIONS: This study found that the COVID arm condition is most common following the first mRNA-1273 vaccination in the female and middle-aged group. The correlation between demographic variables and COVID arm risk elucidates that the reaction is a type IV allergic skin reaction.…”
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“…A declining trend for occurrence of seropositive RA in the young and early middle-aged population may reflect change in risk factors.…”
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“…After stratified analysis, the relevance persisted in the male, young and middle-aged, hypertensives with grade 2 HTN, duration of HTN < 3 years, metabolic syndrome and those without statin therapy. …”
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“…INTRODUCTION: This study aims to explore whole-brain resting-state spontaneous brain activity using fractional amplitude of low-frequency fluctuation (fALFF) and regional homogeneity (ReHo) strategies to find differences among age groups within a population ranging from middle age to older adults. METHODS: The sample comprised 112 healthy persons (M = 68.80, SD = 7.99) aged 48–89 who were split into six age groups (< 60, 60–64, 65–69, 70–74, 75–79, and ≥ 80). …”
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“…The NHPs (Macaca fascicularis, cynomolgus) in this study included middle-aged individuals with a high prevalence of the ocular disease. …”
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“…The representative variability pattern is a monotonically increasing pattern that accelerates after middle age. CONCLUSION: DICNAP was able to identify the potential patterns of the changes in the landscape of DNA methylation during aging. …”
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“…BACKGROUND AND OBJECTIVES: Chronic pain, which affects more than 1 in 4 middle-aged and older adults, can have profound implications for everyday behaviors like driving. …”
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