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  1. 13061
    “…METHODS: The current cross-sectional study was performed on 527 middle-aged adults (45.7% women), who were selected through a multistage cluster random-sampling method. …”
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    An Unhealthy Plant-Based Diet Increases Risk of Hypertension but not Framingham Risk Score in Adults
  2. 13062
    “…While great strides have been made to increase men's involvement in health promoting activities by delivering interventions through sports clubs, research has predominantly focused on select behaviours (e.g., physical activity), sub-groups (e.g., sports fans) and predominantly Caucasian, overweight, middle-aged men.…”
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    Promoting men's health through sports clubs: a rapid realist review
  3. 13063
    “…Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease that is observed more frequently in middle-aged women. This disorder is considered an autoimmune disease, since liver injury is sustained by the presence of self-directed antimitochondrial antibodies targeting the bile duct cells. …”
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    Sequence of events leading to primary biliary cholangitis
  4. 13064
    por Wang, Meijian, Lin, Shengyin, Xie, Ruili
    Publicado 2023
    “…We investigated these questions using immunohistochemistry in three age groups of CBA/CaJ mice of either sex, including 2–5 months (young), 17–19 months (middle-age), and 28–32 months (old). Mouse cochleae were cryo-sectioned and triple-stained using antibodies against Tuj1, calretinin (CR) and calbindin (CB), which are reportedly expressed in all type I, subtype I(a), and subtype I(b) SGNs, respectively. …”
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    Apical-basal distribution of different subtypes of spiral ganglion neurons in the cochlea and the changes during aging
  5. 13065
    por Heo, Seung-Jae, Jee, Yong-Seok
    Publicado 2023
    “…Conversely, the capability to complete the five-time chair stand demonstrated a clear incline (32.49 to 56.81%; p = 0.001), starting from the middle-aged group. As for appendicular skeletal muscle mass, there was an evident tendency for it to decrease (−7.08 to −26.62%; p = 0.001) with increasing age. …”
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    Characteristics of Age Classification into Five-Year Intervals to Explain Sarcopenia and Immune Cells in Older Adults
  6. 13066
    “…We recommend that even if there are no gastrointestinal manifestations of GISTs in the offspring of newly mutated NF1 patients, regular review of gastroenteroscopy, imaging examination, and long-term follow-up after middle age are still crucial for the early diagnosis and treatment of NF1-related GISTs.…”
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    Case Report: Multiple gastrointestinal stromal tumors along with numerous cutaneous neurofibromas: a case description and literature analysis
  7. 13067
    “…Previous studies have reported brain atrophy in middle-aged patients with systolic heart failure. In this report, we present the case of a 21-year-old woman with idiopathic dilated cardiomyopathy, cardiac failure, and global cerebral atrophy due to reduced cerebral artery blood flow. …”
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    Direct Link Between Cardiac Failure and Global Cerebral Atrophy in a Young Adult: A Case Report on Reduced Cerebral Artery Blood Flow
  8. 13068
    “…CONCLUSION: AF with BBB was not significantly associated with the recurrence of AF after catheter ablation in middle‐aged patients with low‐risk cardiovascular profile.…”
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    Association of right bundle branch block or intraventricular conduction delay with recurrence of atrial fibrillation after catheter ablation
  9. 13069
    por Lee, Yong-Hwa, Park, Sunmin
    Publicado 2023
    “…This study investigated the impact of genetic and environmental factors on serum propionylcarnitine levels in middle-aged and elderly participants from the Ansan/Ansung cohort of the Korean Genome and Epidemiology Study. …”
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    Genetic and Lifestyle-Related Factors Influencing Serum Hyper-Propionylcarnitine Concentrations and Their Association with Metabolic Syndrome and Cardiovascular Disease Risk
  10. 13070
    “…CONCLUSIONS: Our findings indicate a positive association between elevated zinc intake and a slowdown in the progression of subchondral sclerosis in OA patients, notably among females, middle-aged individuals, and those with higher calcium and magnesium intake. …”
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    The influence of zinc and iron intake on osteoarthritis patients' subchondral sclerosis progression: A prospective observational study using data from the osteoarthritis Initiative
  11. 13071
    por Wu, Xiao-Hong, Chen, Shi-Wei
    Publicado 2023
    “…Multiple myeloma (MM) is a malignant disease characterized by abnormal proliferation of plasma cells, which usually occurs in middle-aged and elderly male patients. Bisphosphonates (BP) are commonly used for the treatment of MM bone disease. …”
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    Multiple myeloma identified within the same site of the mandible with medication-related osteonecrosis of jaw: An unusual case report
  12. 13072
    “…The study objectives were to determine cognitive trajectories in middle-aged and elderly Chinese individuals, as well as to examine differences in physical performance across cognitive trajectory groups. …”
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    Exploring cognitive trajectories and their association with physical performance: evidence from the China Health and Retirement Longitudinal Study
  13. 13073
    “…Methods: From June 2020 to December 2021, a total of 50 subjects were enrolled in this study, of whom 20 patients with DLS served as the case group and 30 middle-aged and elderly patients with LSS were selected as the control group according to the general conditions (sex, age, and BMI) of the case group. …”
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    Lasso Analysis of Gait Characteristics and Correlation with Spinopelvic Parameters in Patients with Degenerative Lumbar Scoliosis
  14. 13074
    “…CONCLUSION: Chest CT was excessively used during the COVID-19 pandemic. Young and middle-aged people were exposed more than others. The impact of COVID-19-pandemic-related radiation exposure on public health should be followed carefully in future years.…”
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    Did radiation exposure increase with chest computed tomography use among different ages during the COVID-19 pandemic? A multi-center study with 42028 chest computed tomography scans
  15. 13075
    “…T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL) is an extremely rare and aggressive subtype of diffuse large B-cell lymphoma (DLBCL) that typically presents in middle-aged patients and carries a poor prognosis. Hypercalcemia presenting as the initial manifestation of the disease is rare, with only one other case reported in the literature. …”
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    Catch the Calcium: T-Cell Histiocyte-Rich B-Cell Lymphoma Presenting as Hypercalcemia
  16. 13076
    “…BACKGROUND: Research from various countries has shown increases in alcohol- and drug-related deaths and suicide, known as ‘deaths of despair’ over recent decades, particularly among low-educated middle-aged individuals. However, little is known about trends in death-of-despair causes in Spain. …”
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    Trends in cause-specific mortality: deaths of despair in Spain, 1980–2019
  17. 13077
    “…INTERPRETATION: Antihypertensive treatment of adults with SBP/DBP of 130–139/80–89 mmHg and high cardiovascular risk would gain substantial benefits with cost-effectiveness. The young and middle-aged population would derive the most benefit. …”
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    Cost-effectiveness of treatment in adults with blood pressure of 130–139/80–89 mmHg and high cardiovascular risk in China: a modelling study
  18. 13078
    “…We assessed the impact of obesity on the development of DM for two age groups (40-year-old, middle age; 66-year-old, older adults) in the Korean population. …”
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    Differential Impact of Obesity on the Risk of Diabetes Development in Two Age Groups: Analysis from the National Health Screening Program
  19. 13079
    “…In this study, we investigated whether this ALAD polymorphism is associated with altered levels of lead in bone and blood among 726 middle-aged and elderly men who had community (nonoccupational) exposures to lead. …”
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    The delta-aminolevulinic acid dehydratase (ALAD) polymorphism and bone and blood lead levels in community-exposed men: the Normative Aging Study.
  20. 13080
    por Tyczynski, Jerzy E, Berkel, Hans J
    Publicado 2005
    “…The exceptions are the rates in young and middle-aged African Americans. CONCLUSION: Although direction of time trends in Ohio are similar in Ohio and the whole US, Ohio still have cancer mortality rates higher than the US average. …”
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    Long-term all-sites cancer mortality time trends in Ohio, USA, 1970–2001: differences by race, gender and age
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