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  1. 13161
    “…We used prospective data to examine whether body mass index (BMI) increased more following hysterectomy with and without bilateral oophorectomy compared to natural menopause among middle-aged women. METHODS: BMI was assessed annually for up to 10 years in the Study of Women’s Health Across the Nation (SWAN (n=1962). …”
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    Body Mass Index Following Natural Menopause and Hysterectomy with and without Bilateral Oophorectomy
  2. 13162
    “…METHODS AND RESULTS: We analyzed 14 493 baseline stroke-free middle-aged individuals in the ARIC public-use data. …”
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    Premature Cardiac Contractions and Risk of Incident Ischemic Stroke
  3. 13163
    “…Previously, we showed that familial longevity is marked by a more beneficial glucose metabolism already at middle age. As glucose is also related to skin aging, this study aimed to investigate the association between glucose metabolism and perceived age. …”
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    High serum glucose levels are associated with a higher perceived age
  4. 13164
    “…METHODS: Fish oil n-3 PUFA (3g daily) were consumed during 5weeks separated by a 5 week washout period in a cross-over placebo controlled study, including 40 healthy middle aged to elderly subjects. Cognitive performance was determined by tests measuring working memory (WM) and selective attention. …”
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    Effects of supplementation with n-3 polyunsaturated fatty acids on cognitive performance and cardiometabolic risk markers in healthy 51 to 72 years old subjects: a randomized controlled cross-over study
  5. 13165
    “…RESULTS: Although diverse in their characteristics, the patients were over represented by females, young to middle aged, and people on public support. The patients were mostly referred to the team by self/family members and primary care physicians. …”
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    A crisis resolution and home treatment team in Norway: a longitudinal survey study Part 1. Patient characteristics at admission and referral
  6. 13166
    “…CONCLUSIONS: The important risk factors for appearance of BE in GERD patients were male sex, middle age, smooking and alcohol consumption. Obesity is an important factor for development of BE. …”
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    What are Predictive Factors for Developing of Barrett’s Esophagus in Patients with Gerd–our Experience
  7. 13167
    “…The absence of either a switch effect in the young group and the P3 slowing in middle-aged group indicate that switching was not particularly demanding for these participants. …”
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    The Effects of Aging on Conflict Detection
  8. 13168
    “…Conclusion: Three mechanisms may contribute to lower Pap testing among middle-aged first-generation Chinese immigrants: preference for Chinese medicine philosophy, perceived sexualization of Pap testing, and the institutionalization of medical care. …”
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    Cervical Cancer Screening and Chinese Women: Insights from Focus Groups
  9. 13169
    “…RESULTS: Thirty-seven (84.1%) of 44 eligible patients, predominantly female, middle-aged, Bolivians at the indeterminate stage, were enrolled. …”
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    Serological and parasitological response in chronic Chagas patients 3 years after nifurtimox treatment
  10. 13170
    “…The highest risk was found in middle-aged men and was consistently increased throughout the 13-year period of observation. …”
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    New-Onset Atrial Fibrillation Is a Predictor of Subsequent Hyperthyroidism: A Nationwide Cohort Study
  11. 13171
    “…In contrast, ceruloplasmin levels were strikingly higher in neocortex at all ages and rose linearly until middle age. PA28 levels rose with age and were higher in allocortex in vivo, also paralleling in vitro data. …”
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    Neocortex and Allocortex Respond Differentially to Cellular Stress In Vitro and Aging In Vivo
  12. 13172
    “…From 2000, mortality rates levelled off in the youngest groups but accelerated in middle aged and older groups. Mortality analyses by small areas could provide potentially valuable insights into possible drivers of inequalities, and thus inform future strategies to reduce CHD mortality across all social groups.…”
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    Unequal Trends in Coronary Heart Disease Mortality by Socioeconomic Circumstances, England 1982–2006: An Analytical Study
  13. 13173
    “…Circulating intact FGF-23 (iFGF-23) and C-terminal (CtFGF-23) concentrations (ELISA) were measured in 133 middle aged men from the general population in association with insulin sensitivity (Cohort 1); and in association with fat mass and bone mineral density (DEXA) and atherosclerosis (intima media thickness, IMT) in 78 subjects (52 women) with a wide range of adiposity (Cohort 2). …”
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    Iron and Obesity Status-Associated Insulin Resistance Influence Circulating Fibroblast-Growth Factor-23 Concentrations
  14. 13174
    “…This increased ratio was accompanied by reduced levels of oxidative DNA damage in established CD4(+) human T cell clones, from a young or a middle-aged donor. Additionally, cultures of primary human peripheral blood mononuclear cells and CD4(+) T cells from donors aged 25–30 or 55–60 years were also supplemented with these agents. …”
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    An investigation of the effects of the antioxidants, ebselen or N-acetyl cysteine on human peripheral blood mononuclear cells and T cells
  15. 13175
    por Hong, Hua, Wang, Hongxuan, Liao, Huanquan
    Publicado 2013
    “…CONCLUSION: Prehypertension is associated with significantly increased carotid atherosclerotic plaque and is a primary stratify risk factor for carotid atherosclerosis which could cause ischemic stroke in middle-aged and elderly population in Southern China.…”
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    Prehypertension is associated with increased carotid atherosclerotic plaque in the community population of Southern China
  16. 13176
    “…The association of HCV RNA with CMV IgG differed by age (P (interaction) = 0.0007), with a strong association observed among women in the low and middle age tertiles (≤45.3 years of age; β = 6.21, 95% CI:3.30 – 9.11, P<0.0001) but not among women in the high age tertile. …”
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    Hepatitis C Viremia Is Associated with Cytomegalovirus IgG Antibody Levels in HIV-Infected Women
  17. 13177
    “…BMI means increased in parallel across most baseline BMI weight classifications, except for more rapid increases through middle-age for obese women followed by declines in the last wave. …”
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    Population Trends and Variation in Body Mass Index from 1971 to 2008 in the Framingham Heart Study Offspring Cohort
  18. 13178
    “…The model with waist circumference, triglycerides/HDL-C ratio, fasting plasma glucose and mean artery pressure fits middle-aged men.…”
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    Evaluation of two single-factor models of metabolic syndrome: a confirmatory factor analysis for an adult population in Beijing
  19. 13179
    “…METHODS: This was a prospective cohort study: the Copenhagen Male Study, a longitudinal study of healthy middle-aged employed men. Subjects with sinus rhythm and without known cardiovascular disease or diabetes were included. …”
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    Elevated resting heart rate, physical fitness and all-cause mortality: a 16-year follow-up in the Copenhagen Male Study
  20. 13180
    “…Hospitalisation rates increased during the study period for both males and females, with the highest rate of 3.0 hospitalisations per 100,000 population among elderly men, but the most pronounced average increase of 6.4%/year among females, particularly those of young and middle age, and hospitalisations associated with cystic fibrosis. …”
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    Burden and trends of hospitalisations associated with pulmonary non-tuberculous mycobacterial infections in Germany, 2005–2011
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