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  1. 15081
    “…BACKGROUND: This case report describes a neck abscess caused by a strain of Hypervirulent Klebsiella pneumoniae in a middle aged man with diabetes without a history of travel to East and South East Asia. …”
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    A case of neck abscess caused by rare hypervirulent Klebsiella pneumoniae, capsular type K20 and sequence type 420
  2. 15082
    “…Among non-users, awareness was more among middle-aged, more educated, rich participants of west India. …”
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    Awareness regarding the adverse effect of tobacco among adults in India: findings from secondary data analysis of Global Adult Tobacco Survey
  3. 15083
    “…METHODS: In the present study, we explored the psychometric performance of the GAS-10 in the elderly through Item Response Theory in a sample of 1200 Italian community-dwelling middle-aged and elderly adults (53.8% males, mean age = 65.21 ± 9.19 years). …”
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    Psychometric properties and diagnostic accuracy of the short form of the geriatric anxiety scale (GAS-10)
  4. 15084
    “…A proactive screening tool using a non-invasive, easy-to-use method is required to assess the risk focused on musculoskeletal health for primary prevention. However, middle-aged adults have insufficient awareness of musculoskeletal disorders. …”
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    Empirical study of the 30-s chair-stand test as an indicator for musculoskeletal disorder risk of sedentary behaviour in Japanese office workers: a cross-sectional empirical study
  5. 15085
    “…METHODS: A six-week randomized, double-blind, placebo-controlled, four-arm clinical trial including 48 young and middle-aged recreationally trained runners of the Guangzhou Pearl River running team was conducted. …”
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    Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study
  6. 15086
    por Xu, Lingqian, Polya, David A.
    Publicado 2020
    “…According to the results, a negative but not significant relationship was found between hypertension risks and E-iAs(ing,rice) after adjusting for major risk factors, notably age, gender, diabetes and obesity, with relatively higher risks being observed for male, middle-aged, overweight, alcohol consumer or Asian or Asian British, Black or Black British and mixed ethnic groups. …”
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    Exploratory study of the association in the United Kingdom between hypertension and inorganic arsenic (iAs) intake from rice and rice products
  7. 15087
    “…OBJECTIVE: Knee osteoarthritis (KOA) is prevalent in middle-aged and elderly people. This condition negatively affects the quality of life of patients. …”
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    Efficacy of Acupuncture-Related Therapy in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis of Randomized Controlled Trials
  8. 15088
    “…Furthermore, receiver operating characteristic analysis showed that the TyG-BMI could better predict the risk of NAFLD than other traditional indicators [TyG-BMI (AUC): 0.886; 95% CI: 0.8797–0.8927; P < 0.0001], particularly among young and middle-aged and non-obese people. CONCLUSIONS: This epidemiological study is the first on the association between the TyG-BMI and NAFLD risk in the general population. …”
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    Usefulness of the triglyceride glucose-body mass index in evaluating nonalcoholic fatty liver disease: insights from a general population
  9. 15089
    “…Predictors of persistent symptoms included provider-assessed moderate–severe illness (adjusted odds ratio [aOR], 3.24; 95% CI, 1.75–6.02), female sex (aOR, 1.99; 95% CI, 0.98–4.04; >90 days out: aOR, 2.24; 95% CI, 1.01–4.95), and middle age (aOR, 2.08; 95% CI, 1.07–4.03). Common symptoms associated with reports of worse physical health included weakness, fatigue, myalgias, and mental fog. …”
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    Postacute Sequelae of SARS-CoV-2 Infection and Impact on Quality of Life 1–6 Months After Illness and Association With Initial Symptom Severity
  10. 15090
    “…In-depth interviews were conducted with community members including, young, middle-aged and older adults of both genders. Study data were analysed manually using the conventional content analysis technique. …”
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    Exploring community perceptions, attitudes and practices regarding the COVID-19 pandemic in Karachi, Pakistan
  11. 15091
    “…RESULTS: Aged mice showed reduced skeletal muscle function and levels of Ang-(1–7) expression in comparison to young and middle-aged mice. In ACE2KO mice, skeletal muscle function and MEF2A protein expression were significantly lower than in age-matched wild-type (WT) mice. …”
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    Ang-(1–7) protects skeletal muscle function in aged mice
  12. 15092
    “…Similar image quality measures were assessed from measurements on 13 healthy middle‐aged volunteers. Both simulation and in vivo results showed that D‐DANTE had only slightly lower vessel wall/CSF and vessel wall/blood contrast‐to‐noise ratio values compared with regular DANTE, which originated from a 10%–15% reduction in vessel wall SNR but not from reduced CSF or blood suppression efficiency. …”
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    Double delay alternating with nutation for tailored excitation facilitates banding‐free isotropic high‐resolution intracranial vessel wall imaging
  13. 15093
    “…Here, we report on the characterization of amyloid load in the brains of two transgenic amyloidosis models using positron emission tomography (PET) with florbetaben (FBB), an (18)F-labeled amyloid PET tracer routinely used in AD patients. Young, middle-aged, and old homozygous APP/PS1 mice (ARTE10), old hemizygous APPswe/PS1ΔE9, and old wild-type control mice were subjected to FBB PET using a small animal PET/computed tomography scanner. …”
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    Comparison of the Amyloid Load in the Brains of Two Transgenic Alzheimer’s Disease Mouse Models Quantified by Florbetaben Positron Emission Tomography
  14. 15094
    “…CONCLUSIONS: Baseline SUA levels were associated with higher risk of incident CKD in middle-aged and elderly Chinese adults, and this positive association was confirmed in the meta-analysis of multiple cohort studies. …”
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    Serum uric acid and risk of incident chronic kidney disease: a national cohort study and updated meta-analysis
  15. 15095
    por Zhang, Yunyan, Li, Xuelian, Li, Xinghua
    Publicado 2021
    “…NAFLD induces the hepatic-related cancer deaths mostly in middle-aged men. NAFLD enhanced the inflammatory reaction and oxidative stress in the hepatic tissue. …”
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    Curcumae Ameliorates Diethylnitrosamine-Induced Hepatocellular Carcinoma via Alteration of Oxidative Stress, Inflammation and Gut Microbiota
  16. 15096
    “…This is the first time that serum NfL has been assessed in middle-aged women with a history of adolescent-onset AN. …”
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    Thirty years after anorexia nervosa onset, serum neurofilament light chain protein concentration indicates neuronal injury
  17. 15097
    “…METHODS: This cross-sectional study was performed in the Alzheimer's and Families (ALFA+) cohort, comprising middle-aged cognitively unimpaired participants. CSF neurogranin and growth-associated protein-43 (GAP-43) were measured with immunoassays, and synaptosomal-associated protein-25 (SNAP-25) and synaptotagmin-1 were measured with immunoprecipitation mass spectrometry. …”
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    CSF Synaptic Biomarkers in the Preclinical Stage of Alzheimer Disease and Their Association With MRI and PET: A Cross-sectional Study
  18. 15098
    “…MATERIALS AND METHODS: This study has an observational with case-control characteristic and involved ninety-three middle-aged adults stratified into two groups (control group - CG, n = 34; diabetes group - DG, n = 59). …”
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    High Fasting Glycemia Predicts Impairment of Cardiac Autonomic Control in Adults With Type 2 Diabetes: A Case-Control Study
  19. 15099
    “…CONCLUSION: The detection rate of TN in the PreDM population is high, especially in the IFG+IGT population. Middle-aged and elderly people with hypertension and abnormal glucose and lipid metabolism should be treated reasonably and regularly, and their TN should be screened and followed up.…”
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    The Detection of Thyroid Nodules in Prediabetes Population and Analysis of Related Factors
  20. 15100
    “…Additionally, males had higher disease burdens than females. Middle-aged people with CVDs composed the major subgroup affected by HSBP while older people had the highest ASMRs associated with HSBP. …”
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    Heavy Disease Burden of High Systolic Blood Pressure During 1990-2019: Highlighting Regional, Sex, and Age Specific Strategies in Blood Pressure Control
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