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  1. 15461
    “…CONCLUSION: In most cases, middle age, male, and healthy workers were patients. …”
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    An online observational study assessing clinical characteristics and impacts of the COVID-19 pandemic on mental health: a perspective study from Bangladesh
  2. 15462
    “…RESULTS: The chatbot users spanned all age groups, including middle-aged and older adults. Users consulted the chatbot on a wide range of medical conditions, including those that often entail considerable privacy and social stigma issues. …”
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    Utilization of Self-Diagnosis Health Chatbots in Real-World Settings: Case Study
  3. 15463
    por Eid, Basma G., Abdel-Naim, Ashraf B.
    Publicado 2020
    “…Benign prostatic hyperplasia (BPH) is a serious illness affecting middle-aged and elderly male patients. It is a complication of several diseases including metabolic syndrome. …”
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    Piceatannol Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by Modulation of Nrf2/HO-1/NFκB Axis
  4. 15464
    “…Osteoarthritis (OA), the most common form of arthritis, is a very common joint disease that often affects middle-aged to elderly people. However, current treatment options for OA are predominantly palliative. …”
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    USP7 Inhibition Alleviates H(2)O(2)-Induced Injury in Chondrocytes via Inhibiting NOX4/NLRP3 Pathway
  5. 15465
    “…The Ovid MEDLINE and CINAHL databases were queried using a combination of relevant search terms (including middle aged, aged, older adult, elderly, health coaching, and wellness coaching). …”
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    The Use of Telehealth Technology to Support Health Coaching for Older Adults: Literature Review
  6. 15466
    “…CONCLUSIONS: Selective expression of Hand2 in the mouse SNs from middle age through old age increases muscle mass and force by (i) regulating skeletal muscle sympathetic and motor innervation; (ii) improving acetylcholine receptor stability and NMJ transmission; (iii) preventing inflammation and myofibrillar protein degradation; (iv) increasing autophagy; and (v) probably enhancing protein synthesis.…”
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    Heart and neural crest derivative 2‐induced preservation of sympathetic neurons attenuates sarcopenia with aging
  7. 15467
    “…RESULTS: Across multiple birth cohorts, middle-aged Chinese men have consistently higher risks of starting and resuming heavy drinking and lower probabilities of quitting their current heavy drinking than men in other age groups. …”
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    Patterns of heavy drinking behaviour over age and birth cohorts among Chinese men: a Markov model
  8. 15468
    “…This variant’s rare allele is significantly associated with increased BP in middle-aged men. CONCLUSIONS: These studies demonstrate the importance of phospholemman phosphorylation in the regulation of vascular tone and BP and suggest a novel mechanism, and therapeutic target, for aging-induced essential hypertension in humans.…”
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    Phospholemman Phosphorylation Regulates Vascular Tone, Blood Pressure, and Hypertension in Mice and Humans
  9. 15469
    “…RESULTS: Participants (n = 3223) were middle-aged (56.6 ± 15.1 years of age, mean ± SD) adults with prehypertension (systolic BP (SBP) = 136.9 ± 15.2 mmHg, diastolic BP (DBP) = 83.4 ± 8.7 mmHg). …”
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    Tai Ji Quan as antihypertensive lifestyle therapy: A systematic review and meta-analysis
  10. 15470
    por Matijevic, Stephanie, Ryan, Lee
    Publicado 2021
    “…The present study explored the degree to which age, APOE ε4, and sex exerted global vs. tract specific effects on DTI metrics in cognitively healthy late middle-aged to older adults. Data from 49 older adults (ages 54–92) at two time-points separated by approximately 2.7 years were collected. …”
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    Tract Specificity of Age Effects on Diffusion Tensor Imaging Measures of White Matter Health
  11. 15471
    “…We attempt to use the Score for Trauma Triage for Geriatric and Middle-Aged (STTGMA) tool to predict loss of ambulatory function and need for assistive device use. …”
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    Loss of Ambulatory Level and Activities of Daily Living at 1 Year Following Hip Fracture: Can We Identify Patients at Risk?
  12. 15472
    “…METHODS: A total of 103 middle-aged men who had received a health checkup were included. …”
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    Relationship Between Chronic Periodontitis and Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia
  13. 15473
    “…METHODS: The study population included 2475 young and middle-aged adults (aged 18–65 years at baseline) who completed the questionnaires and physical examinations in the Nutrition and Health Survey in Taiwan from 1993 to 1996. …”
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    The Healthy Taiwanese Eating Approach is inversely associated with all-cause and cause-specific mortality: A prospective study on the Nutrition and Health Survey in Taiwan, 1993-1996
  14. 15474
    “…The most common cause for young and young-old patients was BPPV, and the most common cause for middle-aged and old-old patients was psychogenic/PPPD. …”
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    The Impact of Coronavirus Disease 2019 Epidemic on Dizziness/Vertigo Outpatients in a Neurological Clinic in China
  15. 15475
    “…Background: The purpose of this study was to determine if earlier age of first exposure to football is associated with worse brain health in middle-aged and older adult men who played high school football. …”
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    Age of First Exposure to Football Is Not Associated With Later-in-Life Cognitive or Mental Health Problems
  16. 15476
    “…Further steps are to explore employment of these types of relationships when designing infectious diseases control programs aiming to promote infection-preventive behavior in middle aged-and older individuals.…”
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    Social networks and infectious diseases prevention behavior: A cross-sectional study in people aged 40 years and older
  17. 15477
    “…BACKGROUND: Parkinson’s disease (PD) is a common central nervous system degenerative disease in middle-aged and elderly people. Our study aimed to illuminate the relationship and mechanism of long-chain non-coding RNA SNHG1 and miRNA (miR)-216a-3p in PD. …”
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    Long non-coding RNA SNHG1 mediates neuronal damage in Parkinson’s disease model cells by regulating miR-216a-3p/Bcl-2-associated X protein
  18. 15478
    por Jee, Donghyun, Park, Sunmin
    Publicado 2021
    “…BACKGROUND: The prevalence of cataracts is steadily increasing among the middle-aged and elderly worldwide. We hypothesized that adults aged > 50 years with age-related cataracts (ARCs) have an association with metabolic syndrome (MS) and its components, and MS has interactions with different dietary patterns and lifestyles that affect ARC risk. …”
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    Hyperglycemia and Hypo-HDL-cholesterolemia Are Primary Risk Factors for Age-related Cataract, and a Korean-style Balanced Diet has a Negative Association, based on the Korean Genome and Epidemiology Study
  19. 15479
    “…Conclusions: Elevated BP levels were associated with increased plasma Aβ(1–40) levels in middle-aged and elderly ApoE ε4 non-carriers.…”
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    Blood Pressure Level Is Associated With Changes in Plasma Aβ(1 –40) and Aβ(1–42) Levels: A Cross-sectional Study Conducted in the Suburbs of Xi’an, China
  20. 15480
    “…Of 294 patients, 132 (44.9%) were middle-aged adults (41–60 years) and 107 (36.4%) were older than 60 years. …”
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    Fungal Keratitis in Northern Thailand: Spectrum of Agents, Risk Factors and Putative Virulence Factors
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