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6221por de Wilde, Adriaan H., Zevenhoven-Dobbe, Jessika C., Beugeling, Corrine, Chatterji, Udayan, de Jong, Danielle, Gallay, Philippe, Szuhai, Karoly, Posthuma, Clara C., Snijder, Eric J.“…Here, we investigated the CypA dependence of three distantly related nidoviruses that can all replicate in Huh7 cells: the arterivirus equine arteritis virus (EAV), the alphacoronavirus human coronavirus 229E (HCoV-229E), and the betacoronavirus Middle East respiratory syndrome coronavirus (MERS-CoV). …”
Publicado 2018
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6222por Song, Wenfei, Wang, Ying, Wang, Nianshuang, Wang, Dongli, Guo, Jianying, Fu, Lili, Shi, Xuanling“…Middle East respiratory syndrome coronavirus (MERS-CoV) infects host cells through binding the receptor binding domain (RBD) on its spike glycoprotein to human receptor dipeptidyl peptidase 4 (hDPP4). …”
Publicado 2014
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6223por Woo, Patrick C.Y., Lau, Susanna K.P., Teng, Jade L.L., Tsang, Alan K.L., Joseph, Marina, Wong, Emily Y.M., Tang, Ying, Sivakumar, Saritha, Bai, Ru, Wernery, Renate, Wernery, Ulrich, Yuen, Kwok-Yung“…The recent discovery of Middle East Respiratory Coronavirus and another novel dromedary camel coronavirus UAE-HKU23 in dromedaries has boosted interest in search of novel viruses in dromedaries. …”
Publicado 2014
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6224“…This is particularly illustrated over the last 15 years by the emergence of two zoonotic CoVs, the severe acute respiratory syndrome (SARS)- and Middle East respiratory syndrome (MERS)-CoV. Due to their inherent genetic variability, it is inevitable that new cross-species transmission events of these enveloped, positive-stranded RNA viruses will occur. …”
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6225“…The committee determined that, given their potential to cause a public health emergency and the absence of efficacious drugs and/or vaccines, there is an urgent need for accelerated R&D for (in no order of priority) Crimean-Congo haemorrhagic fever, Ebola virus and Marburg virus disease, Lassa fever, Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS), Nipah and henipaviral diseases, Rift Valley fever and Zika virus disease. …”
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6226“…With the recent emergence of Middle East Respiratory Syndrome coronavirus in humans and the outbreak of devastating porcine epidemic diarrhea coronavirus in swine, therapeutic intervention is urgently needed. …”
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6227por Lei, Jian, Mesters, Jeroen R., Drosten, Christian, Anemüller, Stefan, Ma, Qingjun, Hilgenfeld, Rolf“…The Middle-East Respiratory Syndrome coronavirus (MERS-CoV) causes severe acute pneumonia and renal failure. …”
Publicado 2014
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6228por Liu, William J., Zhao, Min, Liu, Kefang, Xu, Kun, Wong, Gary, Tan, Wenjie, Gao, George F.“…However, other coronaviruses still pose a continuous threat to human health, as exemplified by the recent emergence of Middle East respiratory syndrome (MERS) in humans. The work on SARS-CoV widens our knowledge on the epidemiology, pathophysiology and immunology of coronaviruses and may shed light on MERS coronavirus (MERS-CoV). …”
Publicado 2017
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6229por Kang, Shuntong, Peng, Wenyao, Zhu, Yuhao, Lu, Shiyao, Zhou, Min, Lin, Wei, Wu, Wenfang, Huang, Shu, Jiang, Liping, Luo, Xuan, Deng, Meichun“…Viral respiratory diseases such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) always pose a severe threat to people. …”
Publicado 2020
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6230“…First identified in 2012, Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel virus that can cause acute respiratory distress syndrome (ARDS), multiorgan failure, and death, with a case fatality rate of ~35%. …”
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6231por Böttcher-Friebertshäuser, Eva“…Furthermore, MASPs have been recognized as host cell factors activating respiratory viruses including influenza virus as well as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) coronaviruses. …”
Publicado 2018
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6232por Relich, Ryan F.“…Since the beginning of the twenty-first century, numerous “new” viruses, including the coronaviruses responsible for severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), the 2009 pandemic influenza A virus, and Lujo hemorrhagic fever virus, have made their debut and have proved to be formidable threats to human health. …”
Publicado 2017
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6233por Jazieh, Abdul-Rahman, Alenazi, Thamer H., Alhejazi, Ayman, Al Safi, Faisal, Al Olayan, Ashwaq“…PURPOSE: This study investigated the features of oncology patients with confirmed Middle East respiratory syndrome (MERS) at the Ministry of National Guard Health Affairs-Riyadh during the outbreak of June 2015 to determine the clinical course and outcome of affected patients. …”
Publicado 2020
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6234“…In 2018, we conducted a systematic review to identify priority research questions for Severe Acute Respiratory Syndrome-related coronavirus (SARS-CoV) and Middle East Respiratory Syndrome-related coronavirus (MERS-CoV). …”
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6235por Ahmadzadeh, Jamal, Mobaraki, Kazhal, Mousavi, Seyed Jalil, Aghazadeh-Attari, Javad, Mirza-Aghazadeh-Attari, Mohammad, Mohebbi, Iraj“…Risk factors associated with Middle East respiratory syndrome coronavirus (MERS-CoV) infection outcome were established by analyses of WHO data from September 23, 2012 to 18 June 2018. …”
Publicado 2020
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6236“…OBJECTIVES: The aims of this study were to test the following hypotheses: stigma and hardiness exert both direct effects on mental health and also indirect (mediated) effects on mental health through stress in nurses working at a government-designated hospital during a Middle East Respiratory Syndrome coronavirus (MERS-CoV) epidemic. …”
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6237por Frans, Glynis, Beuselinck, Kurt, Peeters, Bart, Van Ranst, Marc, Saegeman, Veroniek, Desmet, Stefanie, Lagrou, Katrien“…The goal of the study was to adapt our Middle East respiratory syndrome coronavirus (MERS-CoV) lab-developed test (LDT) to 3 “Sample to Result” (S2R) systems: BD MAX (BD), ELITe InGenius (ELITechGroup), and ARIES (Luminex). …”
Publicado 2019
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6238por LIU, Ren-qiang, GE, Jin-ying, WANG, Jin-ling, SHAO, Yu, ZHANG, Hui-lei, WANG, Jin-liang, WEN, Zhi-yuan, BU, Zhi-gao“…Middle East respiratory syndrome coronavirus (MERS-CoV), a member of the Coronaviridae family, is the causative pathogen for MERS that is characterized by high fever, pneumonia, acute respiratory distress syndrome (ARDS), as well as extrapulmonary manifestations. …”
Publicado 2017
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6239por Adney, DR, Brown, VR, van Doremalen, N, Bushmaker, T, Scott, D, de Wit, E, Munster, VA, Bowen, RA“…The Middle East respiratory syndrome coronavirus (MERS CoV) is a novel coronavirus first recognized in 2012 and is associated with severe respiratory disease in humans. …”
Publicado 2015
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6240por Choi, Sungwoon, Lee, Jangho, Kang, Min-Gyu, Min, Hyeyoung, Chang, Yoon-Seok, Yoon, Sungroh“…From May to July 2015, there was a nation-wide outbreak of Middle East respiratory syndrome (MERS) in Korea. MERS is caused by MERS-CoV, an enveloped, positive-sense, single-stranded RNA virus belonging to the family Coronaviridae. …”
Publicado 2017
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