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321“…While for the post transcription factors, miR146a and miR132, the opposite was observed. They were down-regulated in the meningitis group. …”
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322“…We generated single and double deletion mutants of the mir-279 and mir-996 hairpins, and cursory analysis suggested that miR-996 was dispensable. …”
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323por Salah, Zaidoun, Arafeh, Rand, Maximov, Vadim, Galasso, Marco, Khawaled, Saleh, Abou-Sharieha, Samah, Volinia, Stefano, Jones, Kevin B., Croce, Carlo M., Aqeilan, Rami I.“…By contrast, sequestering miR-27a/miR-27a* by sponge technology suppressed OS cells invasion and metastases formation. miR-27a/miR-27a* directly repressed CBFA2T3 expression among other target genes. …”
Publicado 2015
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324por Tong, Dayue, Jin, Yi, Xue, Tianyu, Ma, Xiaoyan, Zhang, Jinxiang, Ou, Xueling, Cheng, Jianding, Sun, Hongyu“…To evaluate the identification method using the microRNA markers miR10b and miR135b to distinguish semen stains from menstrual blood, peripheral blood, vaginal fluid and so on body fluid stains. …”
Publicado 2015
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325por Effatpanah, Hosein, Yadegarazari, Reza, Karami, Manoochehr, Majlesi, Amir, Shabab, Nooshin, Saidijam, Massoud“…Molecular markers such as miRNA (microRNA) can have great importance in the early diagnosis of gastric cancer. Expression of miR-21 and miR-221 are deregulated in many types of human cancers. …”
Publicado 2015
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326por Li, Yanshuang, Zhao, Lianmei, Shi, Bianhua, Ma, Sisi, Xu, Zhenbiao, Ge, Yehua, Liu, Yanxin, Zheng, Dexian, Shi, Juan“…However, systematic studies of the functions and mechanisms of miRNAs in TAMs in tumor tissues are rare. In this study, miR-146a and miR-222 were shown to be significantly decreased in TAMs associated with the up-regulated NF-κB p50 subunit. miR-146a promoted the expression of some M2 macrophage phenotype molecules, and miR-146a antagomir transfected RAW264.7 monocyte-macrophage cells inhibited 4T1 tumor growth in vivo. …”
Publicado 2015
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327por Zhang, Xiaoying, Gee, Harriet, Rose, Barbara, Lee, C. Soon, Clark, Jonathan, Elliott, Michael, Gamble, Jennifer R., Cairns, Murray J., Harris, Adrian, Khoury, Samantha, Tran, Nham“…The 3’UTR of PDCD4 contains three binding-sites for miR-499 and one for miR-21. Using a wild-type and truncated 3’UTR of PDCD4, we demonstrated that the initial suppression of PDCD4 was mediated by miR-21 whilst sustained suppression was mediated by miR-499. …”
Publicado 2016
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328por Navarro, A, Pairet, S, Álvarez-Larrán, A, Pons, A, Ferrer, G, Longarón, R, Fernández-Rodríguez, C, Camacho, L, Monzó, M, Besses, C, Bellosillo, B“…According to the mutational status, three differentially expressed miRNAs, miR-15a (P=0.045), miR-150 (P=0.001) and miR-519a (P=0.036), were identified. …”
Publicado 2016
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329por Tamaddon, Gholamhossein, Geramizadeh, Bita, Karimi, Mohammad Hossein, Mowla, Seyed Javad, Abroun, Said“…The greatest changes were detected in miR-4284 and miR-4484 level in patient’s lymphoma samples. …”
Publicado 2016
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331miR-125b and miR-100 Are Predictive Biomarkers of Response to Induction Chemotherapy in Osteosarcomapor Kubota, Daisuke, Kosaka, Nobuyoshi, Fujiwara, Tomohiro, Yoshida, Akihiko, Arai, Yasuhito, Qiao, Zhiwei, Takeshita, Fumitaka, Ochiya, Takahiro, Kawai, Akira, Kondo, Tadashi“…We found six miRNAs, including miR-125b and miR-100, that were differentially expressed > 2-fold (p < 0.05) in patients who respond poorly to treatment. …”
Publicado 2016
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332por Venø, Morten T., Venø, Susanne T., Rehberg, Kati, van Asperen, Jessy V., Clausen, Bettina H., Holm, Ida E., Pasterkamp, R. Jeroen, Finsen, Bente, Kjems, Jørgen“…Temporal miRNA profiling in the developing embryonic porcine cortex revealed a distinct set of miRNAs, including miR-34c and miR-204, which exhibited a highly specific expression profile across the time of cortical folding. …”
Publicado 2017
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333“…OBJECTIVE: To determine the role of miR-484 and miR-744 in DENV infection and to examine whether DENV infection alters the expression of both miRNAs. …”
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334por Liu, Kejian, Xuekelati, Saiyare, Zhang, Yue, Yin, Yin, Li, Yue, Chai, Rui, Li, Xinwei, Peng, Yi, Wu, Jiangdong, Guo, Xiaomei“…The aim of the current study is to investigate the expression levels of atherosclerosis-associated miR-143 and miR-145 in Hhcy patients and predict the progress of atherosclerosis in Hhcy patients. …”
Publicado 2017
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335por Copier, Camila Uribe, León, Luis, Fernández, Mauricio, Contador, David, Calligaris, Sebastián D.“…Then, selected miRNAs expression in myocardium (at 4 and 16 months) and plasma (at 4, 12 and 16 months) were measured by RT-qPCR. Circulating miR-19b-3p and miR-181b-5p levels were associated with myocardium levels during the development of diabetic cardiomyopathy (in terms of cardiac dysfunction), suggesting that these miRNAs could be suitable biomarkers of this disease in asymptomatic diabetic patients.…”
Publicado 2017
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336“…Four oncogenic microRNAs (miR-155, miR-19a, miR-181b, and miR-24) and one tumor suppressor microRNA (let-7a) were shown to differentiate between high- and low-risk early breast cancer (EBC) and reflect the surgical tumor removal and adjuvant therapy. …”
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337“…Our results attest that three microRNAs (miR-21, miR-155, miR-222) were significantly up-regulated, whilst miR-205 was substantially down-regulated in BC tissues in relation to normal adjoining tissues in a heterogeneous patient cohort. …”
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338“…Early diagnosis will lead to a more effective treatment with much less morbidity. As miR-31 and miR-145 are shown to be directly or indirectly correlated to biological processes involved in endometriosis, the aim of this study was to examine the association of miR-31 and miR-145 expression in plasma with the presence of endometriosis. …”
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339“…The present study investigated the relationship between the expression of miR-146a and miR-146b with the occurrence and prognosis of papillary thyroid carcinoma. …”
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340“…MicroRNAs (miRNAs or miRs) are a class of evolutionarily-conserved small, regulatory non-coding RNAs, 19–3 nucleotides in length, that negatively regulate protein coding gene transcripts’ expression. miR-146 (146a and 146b) and miR-155 are among the first and most studied miRs for their multiple roles in the control of the innate and adaptive immune processes and for their deregulation and oncogenic role in some tumors. …”
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