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Mostrando 421 - 440 Resultados de 59,543 Para Buscar '"Mir"', tiempo de consulta: 0.47s Limitar resultados
  1. 421
    “…In this study we have focused on the imprinted miRNA cluster miR-379/miR-656 on 14q32.31 (hereafter C14) to test their coordinated function. …”
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    Genome-wide analysis reveals downregulation of miR-379/miR-656 cluster in human cancers
  2. 422
    “…We identified the interaction sites of several miRNAs with the mRNAs from paralogs and orthologs of the SPL and HAM genes in A. thaliana. miRNAs from the miR156 and miR157 families in A. thaliana are shown to have binding sites within the mRNAs of SPL genes. …”
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    miR156- and miR171-Binding Sites in the Protein-Coding Sequences of Several Plant Genes
  3. 423
    “…Out of 8 miRNAs selected for validation from PCR array data, miR-205 (p<0.0001), mir-214 (p<0.0001), miR-221(p<0.001) and miR-99b (p<0.0001) were significantly downregulated in PCa tissues. …”
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    MicroRNA Profiling in Prostate Cancer - The Diagnostic Potential of Urinary miR-205 and miR-214
  4. 424
    “…The results showed that miR-361 that predominantly located in nucleus can directly bind to primary transcript of miR-484 (pri-miR-484) and prevent its processing by Drosha into pre-miR-484. miR-361 is able to regulate mitochondrial fission and apoptosis by regulating miR-484 levels. …”
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    MDRL lncRNA Regulates the Processing of miR-484 Primary Transcript by Targeting miR-361
  5. 425
    “…We have previously shown that microRNAs (miRNAs) miR-760, miR-186, miR-337-3p, and miR-216b stimulate premature senescence through protein kinase CK2 (CK2) down-regulation in human colon cancer cells. …”
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    Upregulation of miR-760 and miR-186 Is Associated with Replicative Senescence in Human Lung Fibroblast Cells
  6. 426
    “…METHODS: Total RNA was isolated from whole sera in ERA patients (prior to and after 3 and 12 months of therapy with disease modifying antirheumatic drugs), in patients with established RA and in healthy controls (HC) using phenol–chloroform extraction. Expression of miR-146a, miR-155, miR-223, miR-16, miR-203, miR-132 and miR-124a was analysed by TaqMan Real Time PCR. …”
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    Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis
  7. 427
    “…Hepatitis C virus (HCV) replication is dependent on a liver-specific microRNA (miRNA), miR-122. A recent clinical trial reported that transient inhibition of miR-122 reduced viral titers in HCV infected patients. …”
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    Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors
  8. 428
    “…The aim of this study was to test whether miR-483-3p as well as miR-21 could be plasma biomarkers for PDAC. …”
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    Circulating miR-483-3p and miR-21 is highly expressed in plasma of pancreatic cancer
  9. 429
    “…Intriguingly, both miR-20a, member of the oncogenic miR-17–92 cluster, and miR-290, belonging to the miR-290–295 cluster, are highly expressed in embryonic stem (ES) cells. …”
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    miR-20a and miR-290, multi-faceted players with a role in tumourigenesis and senescence
  10. 430
    “…Using next-generation sequencing to profile miRNA transcriptomes, we demonstrate that miR-26a and miR-384-5p specifically affect the maintenance, but not induction, of LTP and different stages of spine enlargement by regulating the expression of RSK3. …”
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    miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement
  11. 431
    “…RESULTS: High levels of circulating miR-34a and low miR-150 levels distinguished groups of patients with polyps from those with advanced cancer (AUC = 0.904), and low circulating miR-150 levels separated patients with adenomas from those with advanced cancer (AUC = 0.875). …”
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    Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression
  12. 432
    “…A total of eight plasma miRNAs abnormally expressed between BC patients and healthy controls in microarray analysis (i.e., elevated miRNAs for miR-505, miR-363 and miR-663b, and decreased for miR-99a, miR-194, miR-100, miR-497 and miR-1 in BC plasma). …”
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    Circulating miR-497 and miR-663b in plasma are potential novel biomarkers for bladder cancer
  13. 433
    “…We aimed to characterize miR-125b and miR-34a expression in 114 women with different cervical lesions: normal epithelium with (n = 20) and without (n = 29) HPV infection; LSIL (n = 28); HSIL (n = 29); and ICC (n = 8). miRNA expression analysis was performed by comparing the distinct groups with the reference group (women with normal epithelium without HPV). …”
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    miR-34a and miR-125b Expression in HPV Infection and Cervical Cancer Development
  14. 434
    “…Twelve miRs (let-7, miR-16, miR-22, miR-26, miR-93, miR-103, miR-191, miR-192, miR-221, miR-423, miR-425 and miR-451) and RNU6B were selected based on their reported production by lung cells, expression in blood and previous use as a reference miRNA. …”
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    Identification of miR-93 as a suitable miR for normalizing miRNA in plasma of tuberculosis patients
  15. 435
    “…The microRNAs isolated from the exosomes contained mir455, mir29b, mir323-5p and mir466 as quantified by qRTPCR, however, mir29b and mir455 showed highest upregulation. …”
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    Cardiosome mediated regulation of MMP9 in diabetic heart: role of mir29b and mir455 in exercise
  16. 436
    “…Upon inhibition of these miRNAs, HNSCC cell lines exhibited increased sensitivity to cisplatin and reduced matrigel invasion. miRNA knockdown also indicated direct targeting of several tumor suppressor genes by miR-30a and miR-934. CONCLUSIONS: Alcohol induces the dysregulation of miR-30a and miR-934, which may play crucial roles in HNSCC pathogenesis and progression. …”
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    Alcohol-dysregulated miR-30a and miR-934 in head and neck squamous cell carcinoma
  17. 437
    “…In exploring the molecular mechanism by which miR-23a promotes apoptosis, we found that it sensitized the effect of p53 on miR-128 regulation. …”
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    miR-23a binds to p53 and enhances its association with miR-128 promoter
  18. 438
    “…We observed significantly elevated expression of miR-21 and miR-152 in LuCa, CRC, and BrCa when compared with normal controls. …”
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    Evaluation of Plasma miR-21 and miR-152 as Diagnostic Biomarkers for Common Types of Human Cancers
  19. 439
    “…Recently, we demonstrated that regulation of the Gtl2-Dio3 noncoding RNA locus is dependent on the MEF2 transcription factor in cardiac muscle, and that two of its encoded miRNAs, miR-410 and miR-495, induce robust cardiomyocyte proliferation. …”
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    miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy
  20. 440
    “…In contrast, Mir133b and Mir128.2 are mainly expressed in head and trunk musculature. …”
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    MicroRNA Profiling during Craniofacial Development: Potential Roles for Mir23b and Mir133b
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