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Mostrando 561 - 580 Resultados de 59,543 Para Buscar '"Mir"', tiempo de consulta: 0.43s Limitar resultados
  1. 561
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    Retracted: Clinical Potential of miR-451 and miR-506 as a Prognostic Biomarker in Patients with Breast Cancer
  2. 562
    “…AIM: This study aimed to evaluate the expression levels of miR-99b and miR-135b in peritoneal carcinoma and liver metastases associated with Colorectal Cancer (CRC), assess their association with the intracellular signaling pathway proteins Kirsten Rat Sarcoma Virus (KRAS) and Akt, and investigate their effects on survival. …”
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    Effect of the MiR-99b and MiR-135b on peritoneal carcinomatosis and liver metastasis in colorectal cancer
  3. 563
    “…Here, we aim to evaluate the cytotoxic effects of curcumin on the expression of miR-383-5p and miR-708-5p and their target genes in CD44(+) CSCs and CD44(-) non-CSCs isolated from the PC3 prostate cancer cell line. …”
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    Cytotoxicity of curcumin against CD44(±) prostate cancer cells: Roles of miR-383 and miR-708
  4. 564
    “…Furthermore, exosomal miR-1290 and miR-29c-3p exhibited higher diagnostic efficiency in early-stage lung cancer than traditional tumor markers, with AUC values of 0.947 and 0.895, respectively. …”
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    Plasma exosomal miR-1290 and miR-29c-3p as diagnostic biomarkers for lung cancer
  5. 565
    “…MATERIALS: To address this issue, we sought to develop optimized fluorescence reporters that could be expressed in precise cellular subsets and used to accurately quantify miR contents in vivo. RESULTS: Focusing on miR-124, we tested different reporter designs whose efficiency was confirmed in different in vitro settings including cell lines and primary neuronal cultures from different brain structures. …”
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    Optimized miR-124 reporters uncover differences in miR-124 expression among neuronal populations in vitro
  6. 566
    por Song, Guisheng, Wang, Li
    Publicado 2008
    “…Gene cloning revealed that the 3′-coding region of pri-miR-433 served as the promoter region of pri-miR-127. …”
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    Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRγ
  7. 567
    “…The CpG island is unmethylated in human miR-200/miR-141 expressing epithelial cells and in miR-200c/miR-141 positive tumor cells. …”
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    Role for DNA Methylation in the Regulation of miR-200c and miR-141 Expression in Normal and Cancer Cells
  8. 568
    “…Antiapoptotic genes BCL2L2 (encoding Bcl-w) and E2F6 are identified as the targets of miR-205 and miR-31, respectively. By downregulating Bcl-w and E2F6, miR-205 and miR-31 promote chemotherapeutic agents-induced apoptosis in prostate cancer cells. …”
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    Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells
  9. 569
    por Jensen, Kevin P., Covault, Jonathan
    Publicado 2011
    “…We have identified brain-expressed mRNAs from genes including, GPHN, RGS2, HOMER1 and KCC2, which share the same miR-96 and miR-1271 regulatory elements. Interestingly, human miR-1271 is expressed abundantly in brain tissue, where miR-96 is not highly expressed. …”
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    Human miR-1271 is a miR-96 paralog with distinct non-conserved brain expression pattern
  10. 570
    “…BACKGROUND: On the base of the microRNA (miRNA) expression signature of bladder cancer (BC), we found that miR-1 and miR-133a were significantly downregulated in BC. …”
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    The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer
  11. 571
    “…A significant reduction of CDK5R1 mRNA and p35 levels was observed after transfection of SK-N-BE neuroblastoma cells with the miR-103 or miR-107 precursor (pre-miR-103 or pre-miR-107). …”
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    The Role of miR-103 and miR-107 in Regulation of CDK5R1 Expression and in Cellular Migration
  12. 572
    “…Differentiation potential correlated with the absence of expression of a novel miRNA, miR669q, and with down-regulation of miR669a. Other miRNAs are known to promote myogenesis, but only miR669a and miR669q act upstream of myogenic regulatory factors to prevent myogenesis by directly targeting the MyoD 3′ untranslated region. …”
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    miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors
  13. 573
    “…BACKGROUND: MicroRNA expression is severely disrupted in carcinogenesis, however limited evidence is available validating results from cell-line models in human clinical cancer specimens. MicroRNA-21 (mir-21) and microRNA-143 (mir-143) have previously been identified as significantly deregulated in a range of cancers including cervical cancer. …”
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    Expression of Mir-21 and Mir-143 in Cervical Specimens Ranging from Histologically Normal through to Invasive Cervical Cancer
  14. 574
    por Shah, Maitri Y, Calin, George A
    Publicado 2011
    “…A recent study has reported that the miRNAs miR-221 and miR-222 are involved in the promotion of an aggressive basal-like phenotype in breast cancer, functioning downstream of the RAS pathway and triggering epithelial-to-mesenchymal transition. …”
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    MicroRNAs miR-221 and miR-222: a new level of regulation in aggressive breast cancer
  15. 575
    “…Besides the fact that miR-96 and miR-182 belong to the miR-182/183 cluster, their seed region (UUGGCA, nucleotides 2–7) is identical suggesting potential common properties in mRNA target recognition and cellular functions. …”
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    Molecular basis of differential target regulation by miR-96 and miR-182: the Glypican-3 as a model
  16. 576
    “…We demonstrated that, in human umbilical vein endothelial cells, both miR-421 and miR-30c directly interacted with PAI-1 mRNA to inhibit the expression of the associated protein. …”
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    miR-421 and miR-30c Inhibit SERPINE 1 Gene Expression in Human Endothelial Cells
  17. 577
    “…Phenotypic changes induced after heterologous expression of miR-147a strikingly differ from those induced by miR-147b or miR-210. …”
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    “Seed-Milarity” Confers to hsa-miR-210 and hsa-miR-147b Similar Functional Activity
  18. 578
    “…Here, we studied how it affects cellular miRs. Extensive miR profiling of the virus-infected and EBNA2-transfected B lymphoma cells revealed that oncomiR miR-21 is positively regulated by this viral protein. …”
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    Differential regulation of miR-21 and miR-146a by Epstein–Barr virus-encoded EBNA2
  19. 579
    “…This study investigated miR-30a, miR-195 and let-7b as potential of biomarker for acute myocardial infarction (AMI). …”
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    Circulating miR-30a, miR-195 and let-7b Associated with Acute Myocardial Infarction
  20. 580
    “…In plants, the juvenile to adult transition (vegetative phase change) is initiated by a decrease in miR156. In Arabidopsis, we found that exogenous sugar decreased the abundance of miR156, whereas reduced photosynthesis increased the level of this miRNA. …”
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    Sugar promotes vegetative phase change in Arabidopsis thaliana by repressing the expression of MIR156A and MIR156C
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