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59341“…An in-depth analysis shows that two main molecular mechanisms are involved in exosomal modified chemoresistance: (1) translational repression of anti-oncogenes by exosomal microRNAs (miRs) and (2) lack of translational repression of oncogenes by sponging of miRs through long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs). …”
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59342“…Recent evidence suggests that aspects of this time-controlled regulation of gene products rely on post-transcriptional control, and point at micro-RNAs (miRs) and RNA-binding proteins as important players in cortical development. …”
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59343por Pazmiño-Betancourth, Mauro, Ochoa-Gutiérrez, Victor, Ferguson, Heather M., González-Jiménez, Mario, Wynne, Klaas, Baldini, Francesco, Childs, David“…Mid-infrared spectroscopy (MIRS) combined with machine learning analysis has shown potential for quick and efficient identification of mosquito species and age groups. …”
Publicado 2023
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59344“…Here, we review current findings of secreted miRs that have been identified to potentially be useful in predicting implantation outcome using material that can be collected relatively non-invasively. …”
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59345por Khan, Parvez, Siddiqui, Jawed Akhtar, Lakshmanan, Imayavaramban, Ganti, Apar Kishor, Salgia, Ravi, Jain, Maneesh, Batra, Surinder Kumar, Nasser, Mohd Wasim“…The identification of antisense sequences, short interfering RNAs (siRNAs), microRNAs (miRNAs or miRs), anti-miRs, and mRNA-based platforms holds great promise in preclinical and early clinical evaluation against LC. …”
Publicado 2021
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59346por Kanakis, Ioannis, Alameddine, Moussira, Folkes, Leighton, Moxon, Simon, Myrtziou, Ioanna, Ozanne, Susan E., Peffers, Mandy J., Goljanek-Whysall, Katarzyna, Vasilaki, Aphrodite“…Small RNA-sequencing demonstrated DE of multiple miRs, snoRNAs and snRNAs. Bioinformatic analyses of miRs-15a, -34a, -122 and -199a, in combination with known myomiRs, confirmed their implication in key muscle-specific biological processes. …”
Publicado 2021
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59347Bovine leukemia virus tax gene/Tax protein polymorphism and its relation to Enzootic Bovine Leukosis“…The BLV proviral genome, along with structural genes (gag, pro, pol, and env), includes nonstructural ones (R3, G4, tax, rex, AS, pre-miRs (for miRNAs). We have shown in our previous data the association of some pre-miRs-B’ (for BLV miRNA) alleles with leukocyte (WBC – white blood cell) number in BLV-infected cows. …”
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59348“…In most cases, overexpressed circRNAs sequester miRs to cause de-repressed translation of mRNAs that encode oncogenic proteins. …”
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59349por Rothschild, Sacha I.“…Some miRNAs have been categorized as “oncomiRs” as opposed to “tumor suppressor miRs.” This review focuses on the role of miRNAs in the lung cancer carcinogenesis and their potential as diagnostic, prognostic, or predictive markers.…”
Publicado 2013
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59350por Reina-Ortiz, Chantal, Mozas, Mª Pilar, Ovelleiro, David, Gao, Fei, Villalba, Martín, Anel, Alberto“…The down-regulation of miRs-199a, -223, and -340 was also detected and is associated with the promotion of NK cell cytotoxicity. …”
Publicado 2023
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59351“…Expressions of two microRNAs, miRs-31 and 210, were determined in the specimens by qRT-PCR. …”
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59352“…Maps of county age‐adjusted disease rates and MIRs were generated separately for African Americans and Caucasians. …”
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59353“…For evaluating the effect of CT number variations of substituted materials due to energy changing of scanner (kVp) on the dose calculation of TPS, the slices of the scanned phantom at three kVp's were imported into the desired TPSs (MIRS and CorePLAN). Dose calculations were performed on two TPSs. …”
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59354“…At the end of treatment, the MRC score was 5 in the proximal muscles and 2–4 in the distal muscles (the MRC score before the treatment was 3–4 and 1–3, respectively). The MIRS grade improved by 25% compared to baseline for both patients. …”
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59355“…We previously identified a panel of peripheral blood mononucleated cell (PBMC)-miRNA (miRs-19b-3p and -29b-3p) biomarkers for lung cancer. …”
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59356por Sorenson, Eric C., Khanin, Raya, Bamboat, Zubin M., Cavnar, Michael J., Kim, Teresa S., Sadot, Eran, Zeng, Shan, Greer, Jonathan B., Seifert, Adrian M., Cohen, Noah A., Crawley, Megan H., Green, Benjamin L., Klimstra, David S., DeMatteo, Ronald P.“…The regions encoding 71 microRNAs (miRs) were deleted in at least 25% of tumor specimens. …”
Publicado 2017
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59357por Müller Coan, Barbara G., Cesarman, Ethel, Acencio, Marcio Luis, Elgui de Oliveira, Deilson“…We found that cells expressing either LMP1 behave similarly in terms of NF-kB activation and cell migration. Nonetheless, the miRs 100-5p, 192-5p, and 574-3p were expressed at higher levels in cells expressing LMP1 B95.8 compared to M81. …”
Publicado 2022
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59358por Nalluri, Joseph J, Kamapantula, Bhanu K, Barh, Debmalya, Jain, Neha, Bhattacharya, Antaripa, de Almeida, Sintia Silva, Juca Ramos, Rommel Thiago, Silva, Artur, Azevedo, Vasco, Ghosh, Preetam“…A set of miRNAs can be used in this analysis to get the associated diseases for the input group of miRs with ranks and also further analysis can be done to find key miRs or diseases, shortest paths etc. …”
Publicado 2015
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59359“…In this review, we discuss the role and involvement of several microRNAs (miRs) in the heterogeneity and metastasis of hepatocellular carcinoma with a special emphasis on their possible role as a diagnostic and prognostic tool in the risk prediction, early detection, and treatment of hepatocellular carcinoma.…”
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59360“…The function of HMGA was evaluated in conjunction with that of other epigenetic factors such as histones and microRNAs (miRs), taking into consideration the posttranscriptional modifications (PTMs) of histones (acetylation and methylation) and DNA methylation. …”
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