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601por Mogilyansky, Elena, Clark, Peter, Quann, Kevin, Zhou, Honglei, Londin, Eric, Jing, Yi, Rigoutsos, Isidore“…We discuss two interactions involving the miR-19a and miR-19b members of the cluster and the 3′UTR of BRCA2’s mRNA. …”
Publicado 2016
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602por Ji, Qiuhong, Ji, Yuhua, Peng, Jingwen, Zhou, Xin, Chen, Xinya, Zhao, Heng, Xu, Tian, Chen, Ling, Xu, Yun“…The aims of this study were to examine the alternation in serum exosome concentrations and the levels of serum exosomal miR-9 and miR-124, two brain-specific miRNAs, in acute ischemic stroke (AIS) patients and to explore the predictive values of these miRNAs for AIS diagnosis and damage evaluation. …”
Publicado 2016
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603por Metheetrairut, Chanatip, Adams, Brian D., Nallur, Sunitha, Weidhaas, Joanne B., Slack, Frank J.“…As expected, loss of jun-1 resulted in IR sensitivity, similar to the phenotype of cel-mir-237 overexpressors. Since miR-237 is the homologue of human miR-125, we validated our findings in MCF-7 and MDA-MB-231 breast cancer cell lines, which harbor lower hsa-miR-125b levels than normal HMECs. …”
Publicado 2016
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604por He, Yutong, Jin, Jing, Wang, LiQun, Hu, Yuejiao, Liang, Di, Yang, Huichai, Liu, Yueping, Shan, Baoen“…The expression levels of miR-21, miR-31, miR-93 and miR-375 were different when Zn levels were varied in EC cell lines, but only miR-21 and miR-375 were associated with patient characteristics and prognosis in patients with EC from an area of China with a high incidence of EC. …”
Publicado 2016
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605por Faccini, Julien, Ruidavets, Jean-Bernard, Cordelier, Pierre, Martins, Frédéric, Maoret, Jean-José, Bongard, Vanina, Ferrières, Jean, Roncalli, Jérôme, Elbaz, Meyer, Vindis, Cécile“…Multivariate logistic regression analysis revealed that low levels of circulating let-7c, miR-145 and miR-155 were associated with CAD. Receiver operating curves analysis showed that let-7c, miR-145 or miR-155 were powerful markers for detecting CAD. …”
Publicado 2017
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606por Cerutti, Camilla, Edwards, Laura J., de Vries, Helga E., Sharrack, Basil, Male, David K., Romero, Ignacio A.“…This study investigated the regulation of firm leukocyte adhesion to human brain endothelium by two different brain endothelial microRNAs (miRs), miR-126 and miR-126*, that are downregulated by TNFα and IFNγ in a human brain endothelial cell line, hCMEC/D3. …”
Publicado 2017
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607Aneurysm-Specific miR-221 and miR-146a Participates in Human Thoracic and Abdominal Aortic Aneurysmspor Venkatesh, Premakumari, Phillippi, Julie, Chukkapalli, Sasanka, Rivera-Kweh, Mercedes, Velsko, Irina, Gleason, Thomas, VanRyzin, Paul, Aalaei-Andabili, Seyed Hossein, Ghanta, Ravi Kiran, Beaver, Thomas, Chan, Edward Kar Leung, Kesavalu, Lakshmyya“…We observed significant upregulation of miR-221 and downregulation of miR-1 and -133 in TAA specimens. …”
Publicado 2017
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608por Vitiello, Marianna, Tuccoli, Andrea, D’Aurizio, Romina, Sarti, Samanta, Giannecchini, Laura, Lubrano, Simone, Marranci, Andrea, Evangelista, Monica, Peppicelli, Silvia, Ippolito, Chiara, Barravecchia, Ivana, Guzzolino, Elena, Montagnani, Valentina, Gowen, Michael, Mercoledi, Elisa, Mercatanti, Alberto, Comelli, Laura, Gurrieri, Salvatore, Wu, Lawrence W., Ope, Omotayo, Flaherty, Keith, Boland, Genevieve M., Hammond, Marc R., Kwong, Lawrence, Chiariello, Mario, Stecca, Barbara, Zhang, Gao, Salvetti, Alessandra, Angeloni, Debora, Pitto, Letizia, Calorini, Lido, Chiorino, Giovanna, Pellegrini, Marco, Herlyn, Meenhard, Osman, Iman, Poliseno, Laura“…By performing small RNA sequencing on A375 melanoma cells and a vemurafenib-resistant clone that was taken as negative control, we discover miR-204 and miR-211 as the miRNAs most induced by vemurafenib. …”
Publicado 2017
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609“…Different sets of RNA-binding proteins interact with primary miRs (pri-miRs) and precursor-miR transcripts (pre-miRs), controlling their biogenesis post-transcriptionally. …”
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610“…In conclusion, aberrant miR-346 and miR-582-3p expression level in pregnancy was associated with multiple maternal and fetal complications. …”
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611por Vargova, K, Pesta, M, Obrtlikova, P, Dusilkova, N, Minarik, L, Vargova, J, Berkova, A, Zemanova, Z, Michalova, K, Spacek, M, Trneny, M, Stopka, TEnlace del recurso
Publicado 2017
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612por Engkvist, M. E., Stratford, E. W., Lorenz, S., Meza-Zepeda, L. A., Myklebost, O., Munthe, E.“…The microRNAs in the miR-34 family, consisting of miR-34a, miR-34b and miR-34c, are tumour suppressors. …”
Publicado 2017
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613por Lei, Chao, Du, Feng, Sun, Lina, Li, Ting, Li, Tingyu, Min, Yali, Nie, Aiying, Wang, Xin, Geng, Lei, Lu, Yuanyuan, Zhao, Xiaodi, Shi, Yongquan, Fan, Daiming“…We determined that miR-143 and miR-145 were downregulated in GC, and the ectopic expression of miR-143 and/or miR-145 inhibited GC cell migration and metastasis. …”
Publicado 2017
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614por Gutierrez-Camino, Angela, Martin-Guerrero, Idoia, Dolzan, Vita, Jazbec, Janez, Carbone-Bañeres, Ana, Garcia de Andoin, Nagore, Sastre, Ana, Astigarraga, Itziar, Navajas, Aurora, Garcia-Orad, Africa“…We analyzed all variants in pre-miRNAs (MAF > 1%) in two independent cohorts from Spain and Slovenia and inferred their functional effect by in silico analysis. SNPs rs12402181 in miR-3117 and rs62571442 in miR-3689d2 were associated with ALL risk in both cohorts, possibly through their effect on MAPK signalling pathway. …”
Publicado 2018
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615por Palkina, Nadezhda, Komina, Anna, Aksenenko, Maria, Moshev, Anton, Savchenko, Andrei, Ruksha, Tatiana“…MicroRNA (miR)-204-5p was previously identified to be downregulated in melanoma compared with melanocytic nevi. …”
Publicado 2018
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616por Guo, Jian, Liu, Chen, Wang, Wei, Liu, Yan, He, Huiwen, Chen, Chong, Xiang, Rong, Luo, Yunping“…ROC analysis suggested that miR-1915-3p and miR-455-3p had the potential as a promising serum diagnostic and predictive biomarkers of breast cancer. miR-1915-3p was over-expressed in certain human breast cancer cells. …”
Publicado 2018
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617por Cao, Xueliang, Huang, Yong, Xia, Dingguo, Qiu, Zhiyong, Shen, Xingjia, Guo, Xijie, Zhao, Qiaoling“…Results showed that TOR2 is not directly a target gene of BmNPV-miR-415, but its expression is up-regulated by BmNPV-miR-415 via Bmo-miR-5738, which could be induced by BmNPV.…”
Publicado 2017
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618por Lu, Yuzhu, Feng, Zhen, Liu, Xuanyu, Bian, Liying, Xie, Hong, Zhang, Changlun, Mysore, Kirankumar S., Liang, Jiansheng“…When miR393 was up-regulated by various stresses, miR390 expression level fell down. …”
Publicado 2018
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619por Wang, Lu‐Qin, Yu, Peng, Li, Bin, Guo, Yan‐Hua, Liang, Zi‐Rui, Zheng, Ling‐Ling, Yang, Jian‐Hua, Xu, Hui, Liu, Shun, Zheng, Li‐Si, Zhou, Hui, Qu, Liang‐Hu“…Instead, differentiation‐related pathways, such as NFκB, MAPK/Erk and VDR, were markedly repressed by miR‐372/373. Numerous new targets of miR‐372/373 were identified, including SPOP, VDR and SETD7, all of which are factors important for cell differentiation. …”
Publicado 2018
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620por Farroni, Chiara, Marasco, Emiliano, Marcellini, Valentina, Giorda, Ezio, Valentini, Diletta, Petrini, Stefania, D'Oria, Valentina, Pezzullo, Marco, Cascioli, Simona, Scarsella, Marco, Ugazio, Alberto G., De Vincentiis, Giovanni C., Grimsholm, Ola, Carsetti, Rita“…Chromosome 21 (HSA21) encodes two microRNAs (miRs), miR-125b, and miR-155, that regulate B-cell responses. …”
Publicado 2018
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