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55001por Castrignanò, Tiziana, Gioiosa, Silvia, Flati, Tiziano, Cestari, Mirko, Picardi, Ernesto, Chiara, Matteo, Fratelli, Maddalena, Amente, Stefano, Cirilli, Marco, Tangaro, Marco Antonio, Chillemi, Giovanni, Pesole, Graziano, Zambelli, Federico“…BACKGROUND: The advent of Next Generation Sequencing (NGS) technologies and the concomitant reduction in sequencing costs allows unprecedented high throughput profiling of biological systems in a cost-efficient manner. Modern biological experiments are increasingly becoming both data and computationally intensive and the wealth of publicly available biological data is introducing bioinformatics into the “Big Data” era. …”
Publicado 2020
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55002por Wu, Jiaqi, Chen, Xianghong, Lv, Yuan, Gao, Kaixin, Liu, Zehao, Zhao, Yue, Chen, Xiumin, He, Xiaohong, Chu, Yongliang, Wu, Xiaodong, Ou, Aihua, Wen, Zehuai, Zhang, Jianyong, Peng, Jianhong, Huang, Zhisheng, Jakobsson, Per-Johan, Huang, Qingchun, Huang, Runyue“…Background: Traditional Chinese Medicine is complementary and an alternative to modern medicine. The combination therapies of herbal products with disease-modifying anti-rheumatic drugs are gradually and widely adopted in the management of rheumatoid arthritis (RA) in China. …”
Publicado 2020
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55003por Pepper, Niklas Benedikt, Oertel, Michael, Kittel, Christopher, Kröger, Kai Jannes, Elsayad, Khaled, Haverkamp, Uwe, Eich, Hans Theodor“…PURPOSE: Mediastinal radiotherapy (RT), especially when combined with bleomycin, may result in substantial pulmonary morbidity and mortality. The use of modern RT techniques like intensity-modulated radiotherapy (IMRT) is gaining interest to spare organs at risk. …”
Publicado 2020
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55004por pour, Ali Foroughi, Pietrzak, Maciej, Sucheston-Campbell, Lara E., Karaesmen, Ezgi, Dalton, Lori A., Rempała, Grzegorz A.“…BACKGROUND: Developing binary classification rules based on SNP observations has been a major challenge for many modern bioinformatics applications, e.g., predicting risk of future disease events in complex conditions such as cancer. …”
Publicado 2020
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55005por Smittenaar, Peter, Ramesh, B.M., Jain, Mokshada, Blanchard, James, Kemp, Hannah, Engl, Elisabeth, Isac, Shajy, Anthony, John, Prakash, Ravi, Gothalwal, Vikas, Namasivayam, Vasanthakumar, Kumar, Pankaj, Sgaier, Sema K.“…Achieving this change will require training CHWs in counseling and behavior change and providing supervision and modern tools such as apps that can help the CHW keep track of her beneficiaries, suggest behavior change strategies, and direct attention to households that stand to gain the most from support.…”
Publicado 2020
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55006por Volkmann, Ariane, Williamson, Anna-Lise, Weidenthaler, Heinz, Meyer, Thomas P.H., Robertson, James S., Excler, Jean-Louis, Condit, Richard C., Evans, Eric, Smith, Emily R., Kim, Denny, Chen, Robert T.“…In multiple clinical trials with the MVA-BN backbone, more than 7800 participants have been vaccinated, demonstrating a safety profile consistent with other licensed, modern vaccines. MVA-BN has been approved as smallpox vaccine in Europe and Canada in 2013, and as smallpox and monkeypox vaccine in the US in 2019. …”
Publicado 2021
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55007por Moccia, Giuseppina, Motta, Oriana, Pironti, Concetta, Proto, Antonio, Capunzo, Mario, De Caro, Francesco“…Traditional protocols are often not sufficient to protect patients susceptible to serious and life-threatening infections, therefore new strategies for decontaminating hospital environments are crucial to reducing microbial transmission and the spread the nosocomial infections. The adoption of modern technologies is indicated to supplement traditional methods and to improve desired levels of surface disinfection. …”
Publicado 2020
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55008por Choi, Yoonha, Qu, Jianghan, Wu, Shuyang, Hao, Yangyang, Zhang, Jiarui, Ning, Jianchang, Yang, Xinwu, Lofaro, Lori, Pankratz, Daniel G., Babiarz, Joshua, Walsh, P. Sean, Billatos, Ehab, Lenburg, Marc E., Kennedy, Giulia C., McAuliffe, Jon, Huang, Jing“…The BGC was trained and validated on patients in the Airway Epithelial Gene Expression in the Diagnosis of Lung Cancer (AEGIS) trials. A modern patient cohort, the BGC Registry, showed differences in key clinical factors from the AEGIS cohorts, with less smoking history, smaller nodules and older age. …”
Publicado 2020
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55009por Sawano, Mitsuaki, Katsuki, Toshiomi, Kitai, Takeshi, Tamita, Koichi, Obunai, Kotaro, Ikegami, Yukinori, Yamane, Takafumi, Ueda, Ikuko, Endo, Ayaka, Maekawa, Yuichiro, Kawamura, Akio, Fukuda, Keiichi, Kohsaka, Shun“…BACKGROUND: Drug-eluting stent-induced vasospastic angina (DES-VSA) has emerged as a novel complication in the modern era of percutaneous coronary intervention (PCI). …”
Publicado 2020
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55010por Szala, Karolina, Ogonowska, Hanna, Lugowska, Boguslawa, Zmijewska, Barbara, Wyszynska, Renata, Dmochowska-Boguta, Marta, Orczyk, Waclaw, Nadolska-Orczyk, Anna“…RESULTS: We compared expression and crosstalk of the TaCKX GFMs and TaNAC2-5A gene in modern varieties grown in a growth chamber (GC) and in the field and looked for differences in their impact on yield-related traits. …”
Publicado 2020
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55011por Nanvubya, Annet, Wanyenze, Rhoda K., Nakaweesa, Teddy, Mpendo, Juliet, Kawoozo, Barbarah, Matovu, Francis, Nabukalu, Sarah, Omoding, Geoffrey, Kaweesi, Jed, Ndugga, John, Kamacooko, Onesmus, Chinyenze, Kundai, Price, Matt, Van Geertruyden, Jean Pierre“…Concerns about safety and effectiveness of some modern FP methods exist. Misconceptions on effects of FP like sterility, cancers and foetal abnormalities were common. …”
Publicado 2020
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55012“…Therefore, it is very important to identify resistance genes for improving the ability of plants to resist heat stress or cold stress by using modern biotechnology. Members of the C-repeat binding factor/Dehydration responsive element-binding 1 (CBF/DREB1) protein family are related to the stress resistance of many plant species. …”
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55013por Nour, Tahir Yousuf, Farah, Alinoor Mohamed, Ali, Omer Moelin, Osman, Mohamed Omar, Aden, Mowlid Akil, Abate, Kalkidan Hassen“…BACKGROUND: Immunization is one of modern medicine’s greatest achievements in the last three decades. …”
Publicado 2020
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55014por Herkert, Cyrille, Kraal, Jos Johannes, Spee, Rudolph Ferdinand, Serier, Anouk, Graat-Verboom, Lidwien, Kemps, Hareld Marijn Clemens“…Unique to this study is the concept of remote on-demand disease management by a single case manager for both diseases, combined with multidisciplinary meetings. Moreover, modern telemonitoring technology is used instead of, rather than as an addition to, regular care. …”
Publicado 2020
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55015por Wright, Esther Victoria, Musbahi, Omar, Singh, Abhinav, Somashekar, Naresh, Huber, Christopher P., Wiik, Anatole Vilhelm“…BACKGROUND: The coronavirus disease 19 (COVID-19) pandemic has presented modern healthcare with an unprecedented challenge. …”
Publicado 2021
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55016“…We implemented this algorithm in an improved GCSscore R package for analysis of modern oligonucleotide microarrays. GCSscore has multiple methods for grouping individual probes on the ClariomD/XTA chips, providing the user with differential expression analysis at the gene-level and the exon-level. …”
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55017“…Further trials should evaluate the role of WBRT in the modern context.…”
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55018por Naseri, Ardalan, Tang, Kecong, Geng, Xin, Shi, Junjie, Zhang, Jing, Shakya, Pramesh, Liu, Xiaoming, Zhang, Shaojie, Zhi, Degui“…Although complete pedigree information for most individuals is difficult to track beyond a few generations, it is possible to describe a person’s genealogical history using their genetic relatives revealed by identity by descent (IBD) segments—long genomic segments shared by two individuals within a population, which are identical due to inheritance from common ancestors. When modern biobanks collect genotype information for a significant fraction of a population, dense genetic connections of a person can be traced using such IBD segments, offering opportunities to characterize individuals in the context of the underlying populations. …”
Publicado 2021
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55019por Bawah, Ayaga A., Sato, Ryoko, Asuming, Patrick, Henry, Elizabeth G., Agula, Caesar, Agyei-Asabere, Charles, Canning, David, Shah, Iqbal“…METHODS: We estimated discontinuation rates during a 12-month period since starting use by applying single and multiple decrement life table methods to the contraceptive calendar data collected in a survey of women in reproductive age of 15–49 years. RESULTS: Modern contraceptive method use was estimated to be 13.7% at the time of the survey. …”
Publicado 2021
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55020por Lindberg, Jesper, Holmström, Paul, Hallberg, Stefan, Björk-Eriksson, Thomas, Olsson, Caroline E.“…Real data for patients treated in 2015-2016 at a modern RT department in Sweden were used. RT workflow similarity was quantified by averaged pairwise utilization rate differences (%) and the size of corresponding correlation coefficients (r). …”
Publicado 2021
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