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55721por Mutowo, Prudence, Bento, A. Patrícia, Dedman, Nathan, Gaulton, Anna, Hersey, Anne, Lomax, Jane, Overington, John P.“…BACKGROUND: The process of discovering new drugs is a lengthy, time-consuming and expensive process. Modern day drug discovery relies heavily on the rapid identification of novel ‘targets’, usually proteins that can be modulated by small molecule drugs to cure or minimise the effects of a disease. …”
Publicado 2016
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55722“…These studies, which combine traditional methods with modern approaches, illustrate how a molecular understanding of gut microbial xenobiotic metabolism can guide hypothesis-driven research into the roles these reactions play in both microbiota and host biology. …”
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55723por Parczewski, Milosz, Siwak, Ewa, Leszczyszyn-Pynka, Magdalena, Cielniak, Iwona, Burkacka, Ewa, Pulik, Piotr, Witor, Adam, Muller, Karolina, Zasik, Ewelina, Grzeszczuk, Anna, Jankowska, Maria, Lemańska, Małgorzata, Olczak, Anita, Grąbczewska, Edyta, Szymczak, Aleksandra, Gąsiorowski, Jacek, Szetela, Bartosz, Bociąga-Jasik, Monika, Skwara, Paweł, Witak-Jędra, Magdalena, Jabłonowska, Elżbieta, Wójcik-Cichy, Kamila, Kamerys, Juliusz, Janczarek, Małgorzata, Krankowska, Dagny, Mikuła, Tomasz, Kozieł, Katarzyna, Bielec, Dariusz, Stempkowska, Justyna, Kocbach, Aleksandra, Błudzin, Wiesława, Horban, Andrzej“…Introduction: Modern combined antiretroviral therapies (cART) allow to effectively suppress HIV-1 viral load, with the 90% virologic success rate, meeting the WHO target in most clinical settings. …”
Publicado 2017
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55724“…And also, it has proved the old saying in China that Sweet wormwood Daodi herb which has been used to resolve summerheat-heat and prevent malaria, which distributed in central China. But in modern time, Daodi Sweet wormwood herb mainly has been used to extract artemisinin and prevent malaria, so the Daod-region has transferred to the southern China.…”
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55725“…DISCUSSION: The recovery rate in this sample is higher (45.5%) compared to other studies. Modern treatment, as well as keeping the fully recovered in the study, may all contribute to this higher rate of recovery. …”
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55726por Khatami, Mahin“…Despite better hygiene, modern detection technologies and discovery of antibiotics, baby boomers and subsequent 2–3 generations are sicker than previous generations at same age. …”
Publicado 2018
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55727por Bahamondes, Luis, Villarroel, Claudio, Frías Guzmán, Natalia, Oizerovich, Silvia, Velázquez-Ramírez, Norma, Monteiro, Ilza“…LIMITATIONS, REASONS FOR CAUTION: Knowledge and awareness of the contraceptive method itself and of the mix of individual countries in the region is essential to the development of specific strategies and actions, tailored to each particular country situation, aimed at increasing access to modern contraceptive methods, especially LARC. WIDER IMPLICATIONS OF THE FINDINGS: Healthcare systems in LAC should consider LARC as a primary option for decreasing UP and adolescent pregnancy. …”
Publicado 2018
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55728por Gulzar, Nabila, Rafiq, Saima, Nadeem, Muhammad, Imran, Muhammad, Khalique, Anjum, Muqada Sleem, Iqra, Saleem, Tahir“…Milling pH did not influence C18:1 t10–11 concentration but storage days significantly (p < 0.05) decreased its concentration. CONCLUSION: In modern era, Mozzarella cheese is major source of dietary fatty acids. …”
Publicado 2019
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55729“…Indigo production from plants using traditional methods is a slow process compared to synthetic dyes and is not suitable for modern and rapid industrial production. Therefore, our study records the detailed information of traditional indigo dyeing to protect and inherit it. …”
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55730por Bandi, Archana, Larson, Meg, Beattie, Janice, Summerville, Ashley, Lumley, Brandi, Lutz-McCain, Stacey, B-Kelly, Monique“…Background: Diabetes Care Network (DCN) is a collaborative care pathway that uses a team approach via telehealth to modernize diabetes care delivery and scale the endocrine expertise for complex diabetic patients. …”
Publicado 2019
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55731por Ahlqvist, Göran, Larsson, Jan-Olov, von Rosen, Tatjana, Westling Allodi, Mara, Rydelius, Per-Anders“…BACKGROUND: A curriculum was planned using modern concepts based on the “old” principles to test if such an educational intervention provided pupils with good mental health and a solid basis for good reading and writing skills, as well as generated a positive attitude to learn. …”
Publicado 2019
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55732por Akseer, Nadia, Rizvi, Arjumand, Bhatti, Zaid, Das, Jai K., Everett, Karl, Arur, Aneesa, Chopra, Mickey, Bhutta, Zulfiqar A.“…MAIN OUTCOMES AND MEASURES: Health intervention coverage was examined using 10 standard indicators: contraceptive method (any or modern); antenatal care by a skilled health care professional; facility delivery; skilled birth attendance (SBA); bacille Calmette-Guérin vaccination (BCG); diphtheria, pertussis, and tetanus vaccination (DPT3) or DPT3 plus hepatitis B and poliomyelitis (penta); measles vaccination; care-seeking for acute respiratory infection; oral rehydration therapy for diarrhea; and the Composite Coverage Index. …”
Publicado 2019
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55733por Yan, Dong, Zhao, Li-li, Yue, Bo-wen, Qian, Hui, Zhang, Zi-han, Wang, Ning, Yan, Shi-hai, Qian, Yu-liang“…OBJECTIVE: Coronary heart disease (CHD) has been regarded as a serious and common disease in the modern society. This study aims to investigate the effect of Granule of BU-XIN RUAN-MAI (BXRM) on angina pectoris of coronary heart disease and to explore the molecular mechanisms underlying Granule of BU-XIN RUAN-MAI-mediated protective activity against this disease. …”
Publicado 2019
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55734por Liu, Gang, Li, Xiaoqiang, Qin, An, Zheng, Weili, Yan, Di, Zhang, Sheng, Stevens, Craig, Kabolizadeh, Peyman, Ding, Xuanfeng“…CONCLUSIONS: SPArc could significantly spare OARs while providing a similar or better robust target coverage compared with IMPT in the treatment of bilateral HNC. In the modern proton system with ELST less than 0.5 s, SPArc could potentially be implemented in the routine clinic with a practical, achievable treatment delivery efficiency.…”
Publicado 2020
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55735por Demergazzi, Silvia, Pastore, Luca, Bassani, Giada, Arosio, Marco, Lonati, Caterina“…Novel strategies are required to identify physicians’ real-life needs with the final aim to improve modern medical information delivery. OBJECTIVE: Our research used an innovative tool to collect real-time physician queries in order to investigate information needs and seeking behavior of Italian neurologists treating patients with multiple sclerosis (MS) and migraine. …”
Publicado 2020
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55736por Lin, Xiajing, Gou, Zhongyong, Wang, Yibing, Li, Long, Fan, Qiuli, Ding, Fayuan, Zheng, Chuntian, Jiang, Shouqun“…It is important, therefore, to accurately re-evaluate and satisfy the Fe requirements of modern broiler chicken, and especially important, non-Western breeds such as Chinese yellow broilers, for their optimal growth and health. …”
Publicado 2020
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55737por Acaralp-Rehnberg, Lydia K., Coleman, Grahame J., Magrath, Michael J. L., Melfi, Vicky, Fanson, Kerry V., Bland, Ian M.“…SIMPLE SUMMARY: Live animal encounter programs are an increasingly popular occurrence in the modern zoo. The effects of such encounters on program animal welfare have not been studied extensively to date. …”
Publicado 2020
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55738por Starzer, Marie, Hjorthøj, Carsten, Albert, Nikolai, Nordentoft, Merete, Lund Sørensen, Helene“…The 20 year OPUS follow-up will give us the first opportunity to assess the long term outcome in a large representative cohort treated within modern mental health services with treatment available for all. …”
Publicado 2020
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55739por Selvaraj, Michael Gomez, Valderrama, Manuel, Guzman, Diego, Valencia, Milton, Ruiz, Henry, Acharjee, Animesh“…CONCLUSION: UAV platforms, time series image acquisition, automated image analytical framework (CIAT Pheno-i), and key vegetation indices (VIs) to estimate phenotyping traits and root yield described in this work have great potential for use as a selection tool in the modern cassava breeding programs around the world to accelerate germplasm and varietal selection. …”
Publicado 2020
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55740“…S.M.N. reports personal fees from Access Fertility, personal fees from Merck, personal fees from Ferring, grants and personal fees from Roche Diagnostics, personal fees from The Fertility Partnership and personal fees from Modern Fertility, outside the submitted work. T.C. reports personal fees from Merck and personal fees from Ferring, outside the submitted work. …”
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