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481por Serce Pehlevan, Ozge, Benzer, Derya, Gursoy, Tugba, Karatekin, Guner, Ovali, Fahri“…The outcome measures were the incidence of NEC stage ≥2 or late-onset cultureproven sepsis and NEC stage ≥2 or death. …”
Publicado 2020
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482por Sodhi, Chhinder P., Wipf, Peter, Yamaguchi, Yukihiro, Fulton, William B., Kovler, Mark, Niño, Diego F., Zhou, Qinjie, Banfield, Emilyn, Werts, Adam D., Ladd, Mitchell R., Buck, Rachael H., Goehring, Karen C., Prindle, Thomas, Wang, Sanxia, Jia, Hongpeng, Lu, Peng, Hackam, David J.“…OBJECTIVE: Necrotizing enterocolitis (NEC) develops through exaggerated toll-like receptor 4 (TLR4) signaling in the intestinal epithelium. …”
Publicado 2020
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483“…BACKGROUND: Necrotizing enterocolitis (NEC), while classically discussed in preterm and low birth weight neonates, also occurs in the term infant and accounts for 10% of all NEC cases. …”
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484por Ouyang, Yulin, Wen, Li, Armstrong, Jane A., Chvanov, Michael, Latawiec, Diane, Cai, Wenhao, Awais, Mohammad, Mukherjee, Rajarshi, Huang, Wei, Gough, Peter J., Bertin, John, Tepikin, Alexei V., Sutton, Robert, Criddle, David N.“…Nec-1 markedly ameliorated histological and biochemical changes in all models. …”
Publicado 2021
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485por Sun, Qian, Ji, Yan-Chun, Wang, Zheng-Li, She, Xiang, He, Yu, Ai, Qing, Li, Lu-Quan“…OBJECTIVE: To determine the role of sodium butyrate in intestinal inflammation via regulation of high-mobility group box-1 (HMGB1), we analyzed the potential mechanism in necrotizing enterocolitis (NEC) in a neonatal mouse model. METHODS: A NEC model was created with hypoxia and cold exposure and artificial overfeeding. …”
Publicado 2021
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486por Yu, Shenghua, Lv, ZhiBao, Gao, Zhimei, Shi, Jingyi, Sheng, Qingfeng, Zheng, Lulu, Zhou, Junmei, Wang, Xueli“…Background: Hydrogen is protective against intestinal injury in necrotizing enterocolitis (NEC), mainly through to alleviate inflammation response. …”
Publicado 2021
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487“…(1) Background: Necrotizing enterocolitis (NEC) is one of the leading causes of death in newborns despite improvements in the care of critically ill neonates. …”
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488por Yan, Xiaocai, Managlia, Elizabeth, Zhao, You-Yang, Tan, Xiao-Di, De Plaen, Isabelle G.“…Necrotizing enterocolitis (NEC) is a deadly bowel necrotic disease of premature infants. …”
Publicado 2022
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489“…OBJECTIVE: Necrotizing enterocolitis (NEC) is a serious neonatal disease; this study aims to investigate the role of sulforaphane (SFN) in NEC-induced intestinal injury. …”
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490“…BACKGROUND: The current indications based on the clinicopathological parameters for predicting the need for surgery in neonatal necrotizing enterocolitis (NEC) are still limited. This study retrospectively analyzes the characteristics of neonatal NEC and aims to identify the risk factors for surgical intervention in NEC. …”
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491por Pei, Xiaojing, Gao, Yujun, Kou, Yan, Ding, Yanjie, Li, Dan, Lei, Peng, Zuo, Lili, Liu, Qiongyu, Miao, Naiying, Reddy, Simmy, Yu, Yonghui, Sun, Xuemei“…Objective: To assess the risk of necrotizing enterocolitis (NEC) and explore the relationship between antibiotic overexposure and disease occurrence in a large prospective birth cohort. …”
Publicado 2022
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492“…RESULTS: Among 104 NEC neonates, the admission age was 7.5 days and the weight was 2.03 kg. …”
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493por Duess, Johannes W., Sampah, Maame E., Lopez, Carla M., Tsuboi, Koichi, Scheese, Daniel J., Sodhi, Chhinder P., Hackam, David J.“…Necrotizing enterocolitis (NEC) is a devastating disease in premature infants and the leading cause of death and disability from gastrointestinal disease in this vulnerable population. …”
Publicado 2023
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494Programmed death of intestinal epithelial cells in neonatal necrotizing enterocolitis: a mini-reviewpor Yang, Shuo, Wei, Xin, Zhong, Yuting, Guo, Conglu, Liu, Xinzhu, Wang, Zhibin, Tu, Ye“…Necrotizing enterocolitis (NEC) is one of the most fatal diseases in premature infants. …”
Publicado 2023
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495por Chen, Qin, Yao, Weiquan, Xu, Fengdan, Liao, Jinfeng, Li, Jinfeng, Mai, Minling, Xie, Haoqiang, He, Xiaoguang, Li, Ning“…Abdominal ultrasound (AUS) has been shown to provide benefits in diagnosing and managing NEC in recent years. OBJECTIVE: This study focused on the utility of AUS in the diagnosis and evaluation of surgical NEC. …”
Publicado 2023
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496por Stanikova, Andrea, Jouza, Martin, Bohosova, Julia, Slaby, Ondrej, Jabandziev, Petr“…Although necrotising enterocolitis (NEC) is a serious, life-threatening disease, improved neonatal care is increasing the number of survivors with NEC among extremely preterm neonates. …”
Publicado 2023
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497“…Previous studies showed that intestinal-fatty acid binding protein (I-FABP) may be a valid and promising serologic biomarker for early diagnosis of necrotizing enterocolitis (NEC). Objective. To investigate the early diagnostic value of serologic I-FABP in NEC for the premature neonates. …”
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498por Jie, Hongyu, He, Yi, Huang, Xuechan, Zhou, Qingyou, Han, Yanping, Li, Xing, Bai, Yongkun, Sun, Erwei“…We showed that Nec-1 markedly enhanced the resolution of established neutrophil-dependent inflammation in LPS-induced acute lung injury in mice. …”
Publicado 2016
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499“…We found that β-arrestin-2 was overexpressed in both human and murine NEC samples. β-arrestin-2-deficient mice were protected from endoplasmic reticulum stress and NEC development. …”
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500“…Necrostatin-1 (Nec-1) is a RIP1-targeted inhibitor of necroptosis, a form of programmed cell death discovered and investigated in recent years. …”
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