“…The study provides insights into the design and optimization of antimicrobial peptides to achieve improved stability and therapeutic efficacy. TA4(dK), C10:0-A2(6-NMeLys), and C10:0-A2(9-NMeLys) were identified as the most promising molecules for further studies.…”
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“…A two-step mechanism was studied by quantum-chemical calculations using Ace-Asn-Nme (Ace = acetyl, Nme = NHCH(3)) as a model compound. …”
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“…The calculations were performed for Ace−Asn−His−Nme (Ace = acetyl, Nme = methylamino) as a model compound by the density functional theory with the B3LYP functional and the 6-31+G(d,p) basis set. …”
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“…Herein we report our first investigations of radicals derived from phosphasilenes with Mes, Tip, Dur, and NMe(2) substituents on the P atom, using muon spin spectroscopy and DFT calculations. …”
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“…(C(6)F(5))Te(CH(2))(3)NMe(2) (1), a perfluorophenyltellurium derivative capable of forming intramolecular N⋅⋅⋅Te interactions, was prepared and characterized. …”
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“…Herein, the trichlorine monoanions in 2‐chloroethyltrimethylammonium trichloride [NMe(3)EtCl][Cl(3)], 1, tetramethylammonium trichloride [NMe(4)][Cl(3)], 2, and tetrapropylammonium trichloride [NnPr(4)][Cl(3)], 3, are analysed. …”
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“…In all cases, separation selectivity increased in the order of dipropylamine < di-sec-butylamine < CyNMe(2) < TEPDA, i.e., TEPDA was best suited for the separation of hydrocarbons and their derivatives. …”
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“…Results  Three thousand one hundred fifty-seven endoscopy-related certifications were awarded to 1928 trainees from gastroenterology (52.3 %), GS (28.4 %) and NME (16.5  %) specialties. During the study period, certification numbers increased for all modalities and specialties, particularly NME trainees. …”
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“…Despite relatively mild work-up conditions the pentaborate(1-) salts prepared were not always as anticipated and the following compounds were isolated in good yield: [Me(2)NH(CH(2))(2)NHMe(2)][B(5)O(6)(OH)(4)](2) (1), [Et(2)NH(CH(2))(2)NHEt(2)][B(5)O(6)(OH)(4)](2) (2), [Et(2)NH(2)][B(5)O(6)(OH)(4)] (3), [Me(2)NH(2)][B(5)O(6)(OH)(4)] (4), [Me(2)NH(CH(2))(3)NHMe(2)][B(5)O(6)(OH)(4)](2) (5), [Et(2)NH(CH(2))(3)NHEt(2)][B(5)O(6)(OH)(4)](2) (6), [Me(3)NCH(2)CH=CH(2)][B(5)O(6)(OH)(4)] (7), and [Me(3)N(CH(2))(3)NMe(3)] [B(5)O(6)(OH)(4)](2)(.)0.5H(2)O (8). The tetraborate(2-) salt, [Me(3)N(CH(2))(2)NMe(3)][B(4)O(5)(OH)(4)](.)2B(OH)(3)(.)2H(2)O (9) was obtained in moderate yield (41%) from a 3:1 reaction of B(OH)(3) with [Me(3)N(CH(2))(2)NMe(3)](OH)(2). …”
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“…The structures of H(2)B(μ-NMe(2))(2)BH(I) and [(μ-NMe(2))BH(NTf(2))](2) indicated a sterically crowded environment around boron, and this leads to the less common O-bound mode of NTf(2) binding. …”
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“…Conclusion: STEAP1, TOMM20, GLT8D2, and NME5 were identified as potential biomarkers and therapeutic targets for adenomyosis. …”
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“…Importantly, transcriptome profiling and mechanistic assays unveil that YTHDC1 in macrophages regulates Ras homolog family member H (RHOH) to suppress inflammatory responses and fine‐tunes NME nucleoside diphosphate kinase 1 (NME1) to enhance the integrity of colonic epithelial barrier, respectively. …”
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“…In this review, we summarize how the HGF/SF transgenic mouse has been used to reveal metastasis-regulating activity of four different genes (CDK4(R24C), survivin and NME1/NME2) in the context of UV-induced melanoma. …”
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“…Reaction of the alkoxydiaminocyclopropenium salt [C(3)(NEt(2))(2)(OMe)](+) with amines led to a series of C(2v)-symmetric salts [C(3)(NEt(2))(2)(NR(2))]DCA (R = Me, Bu, Hex) and two C(s)-symmetric salts and [C(3)(NEt(2))(2)(NRMe)]DCA (R = Me, Bu). Similarly, [C(3)(NMe(2))(2)(OMe)](+), was used to prepare the C(s)-symmetric salts [C(3)(NMe(2))(2)(NRMe)]DCA (R = Pr, Bu). …”
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“…The synthesis and characterization of six new substituted guanidium tetrahydroxidohexaoxidopentaborate(1-) salts are reported: [C(NH(2))(2)(NHMe)][B(5)O(6)(OH)(4)]·H(2)O (1), [C(NH(2))(2)(NH{NH(2)})][B(5)O(6)(OH)(4)] (2), [C(NH(2))(2)(NMe(2))][B(5)O(6)(OH)(4)] (3), [C(NH(2))(NMe(2))(2)][B(5)O(6)(OH)(4)] (4), [C(NHMe)(NMe(2))(2)][B(5)O(6)(OH)(4)]·B(OH)(3) (5), and [TBDH][B(5)O(6)(OH)(4)] (6) (TBD = 1,5,7-triazabicyclo [4.4.0]dec-5-ene). …”
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“…SLOPER presented the highest global (p < 0.001, d ≥ 0.629), FDP (p < 0.001, d ≥ 0.777), FDS (only CRIMP vs SLOPER: p < 0.001, d = 0.140), and EDC NME (p < 0.001, d ≥ 1.194). The CRIMP showed greater FDS activity (p = 0.001, d = 0.386) and lower NME (p = 0.003, d = 0.125) compared to SLOPE. …”
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“…Less improvement in NDI and NME flexion from baseline to 12 months post exercise commencement, along with some baseline covariates were related to persistent dizziness and explained 50% of the variance. …”
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“…The reaction of the orthopalladated complex [Pd(μ-Cl)(C(6)H(4)(CH(CO(2)Me)NMe(2))-2)](2) (1) with nucleophiles HNu under a CO atmosphere results in the selective incorporation of the C(O)Nu moiety to the phenyl ring and formation of the carbonyl species ortho-C(6)H(4)(C(O)Nu)(CH(CO(2)Me)NMe(2)) (2a–j) (Nu = OR, NHR, NR(2)). …”
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“…Based on density functional theory calculations using Ace-Asp-Nme (Ace = acetyl, Nme = NHMe) as a model compound, we propose the possibility that acetic acid (AA), which is often used in protein drug formulation for mildly acidic buffer solutions, catalyzes the succinimide formation from Asp residues by acting as a proton-transfer mediator. …”
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“…Here, it was found that the sub‐cellular distribution of [Os(η(6)‐p‐cym)(Azpy‐NMe(2))I](+) (p‐cym=p‐cymene, Azpy‐NMe(2)=2‐(p‐[dimethylamino]phenylazo)pyridine) (1), a promising drug candidate, can be mapped in human ovarian cancer cells at pharmacological concentrations using a synchrotron X‐ray fluorescence nanoprobe (SXRFN). …”
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