“…According to their properties and obvious alterations during hypobaric hypoxia, changes of plasma concentrations of Ttr, Prdx-2, Gpx -3, Apo A-I, Hp, Apo-E, Fetub and Nme were selected to be validated by Western blot analysis. …”
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“…These proteins mediated many processes, such as glycolysis and energy production (Nme2 and Pnp), cartilage matrix (Col2a1), transcription and protein synthesis (Eef1a1 and DJ-1), signal transduction (CaM and Pebp1), transport (Alb and Hba1), and latexin (Lxn). …”
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“…To validate particular elements in our network, we assessed publicly available ChIP-seq data for BMAL1, REV-ERBα/β and RORα/γ proteins and found strong evidence for circadian regulation of Elavl1, Nme1, Dhx6, Med1 and Rbbp7 all of which are involved in the regulation of tumourigenesis. …”
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“…The Non-NMEs-FDC entered the market at a median of 2.33 years (-7.55, 2.39) before approval of generic single active ingredient. Non-NME-FDC added a median of 9.70 (2.75, 16.24) years to the patent and exclusivity life of the single active ingredients in the combination. …”
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“…Further, cellular levels of protein kinase C epsilon type (PKC-ε) and kinesin heavy chain (KIF5B) increased with time of induction, whereas the level of NME/NM23 nucleoside diphosphate kinase 1 (Nm23-H1) decreased during the time course of differentiation. …”
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“…As a first practical result, three-dimensional swimming trajectories of the cypris larva of the barnacle Semibalanus balanoides are recorded in the vicinity of a glass surface and close to PEG2000-OH and C(11)NMe(3)(+)Cl(−) terminated self-assembled monolayers. …”
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“…The systematic change of electron density of the pyridine nitrogens upon alteration of the para-substituent (NO(2), CF(3), H, F, Me, OMe, NMe(2)) was confirmed by (15)N NMR and by computation of the natural atomic population and the π electron population of the nitrogen atoms. …”
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“…Herein we present our first study of Fe–N( x )H( y ) complexes supported by new tris(phosphine)silyl ligands, abbreviated as [SiPNMe3] and [SiPiPr2P(NMe)], that incorporate remote tertiary amine hydrogen-bond acceptors within a tertiary phosphine/amine 6-membered ring. …”
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“…In addition, coding variants in ZCWPW1 (rs6465770) and NME8 (rs10250905 and rs62001869) showed association with memory endophenotypes. …”
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“…Intrathecal injection of the mu-opioid receptor agonist [D-Ala(2), NMe-Phe(4), Gly-ol(5)]-enkephalin produces paradoxical behavioural responses: early-phase analgesia and late-phase mechanical allodynia which requires NMDAR; both phases are prolonged in Arrb2 knockout (KO) mice. …”
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“…Protein-protein interaction network and functional module analyses identified highly-interconnected “hub” genes (APOE, PICALM, BIN1, ABCA7, CD2AP, CLU, CR1, MS4A4E and MS4A6A) and bottleneck genes (APOE, TOMM40, NME8, PICALM, CD2AP, ZCWPW1, FAM180B, GAB2 and PTK2B) that created three tight subnetworks. …”
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“…The preparation and characterization of a new family of four polyoxothiometalate (POTM) clusters are reported, with varying size and complexity, based upon the dimeric [Mo(2)O(2)S(2)(H(2)O)(6)](2+) cation with the general formula (NMe(4))(a)K(b)[(Mo(2)O(2)S(2))(c)(TeO(4))(d)(C(4)O(4))(e)(OH)(f)] where a,b,c,d,e,f={1,7,14,2,4,10}=1, {Mo(28)Te(2)}; {2,26,36,12,10,48}=2, {Mo(72)Te(12)}; {0,11,15,3,3,21}=3, {Mo(30)Te(3)}; {2,6,12,2,4,16}=4, {Mo(24)Te(2)}. …”
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“…The result predicts a close relationship between an 8-miRNA set (miR-9, miR-490-5p, miR-490-3p, miR-182, miR-34a, miR-196b, miR-34b*, miR-181a-2*) and a 9-mRNA set (CAV2, LAPTM4B, TIMP1, PKIG, WASF1, MMP1, ERVH-4, NME4, HSD17B12). The majority of the identified variables have been linked to hematologic functions by a number of studies. …”
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“…This review discusses the role that the NM23/NME/NDPK phosphotransferase plays, how the addition of the pHis phosphoproteome will expand the phosphoproteome, and make His phosphorylation part of the global phosphorylation world. …”
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“…Racemic and enantiomerically pure titanium(IV) complexes with ortho-brominated or para-nitrated chiral diaminobis(phenolato) ligands were prepared with NH and NMe cyclohexyldiamino bridges through ligand to metal chiral induction. …”
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“…Here, we report the rational design and DNA binding interactions of a novel di-Cu(2+) artificial metallonuclease [Cu(2)(tetra-(2-pyridyl)-NMe-naphthalene)Cl(4)] (Cu(2)TPNap). Cu(2)TPNap is a high-affinity binder of duplex DNA with an apparent binding constant (K(app)) of 10(7) M(bp)(−1). …”
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“…A series of new complexes were synthesized, namely [M(2)L(μ-L')](+) (L' = azo-H, M = Cd (1), Ni (2); L' = azo-OH, M = Zn (3), Ni (4); L' = azo-NMe(2), M = Zn (5), Cd (6), Ni (7); L' = azo-CO(2)Me, M = Cd (8), Ni (9)), and characterized by elemental analysis, electrospray ionization mass spectrometry (ESIMS), IR, UV–vis and NMR spectroscopy (for diamagnetic Zn and Cd complexes) and X-ray single crystal structure analysis. …”
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“…Among them, six genes (CLDN3, DECR2, EVA1B, NME4, NTSR1, and XPNPEP2) were highly significantly changed by altered DNA methylation. …”
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“…Finally, to showcase its modularity, we adapted our Cas-ON system to the smaller and more target-specific Neisseria meningitidis (Nme)Cas9 orthologue and its cognate inhibitors AcrIIC1 and AcrIIC3. …”
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