“…Although a subset of genes that related to IHC machinery and deafness were found to be differentially expressed, a gradient of gene expression was indeed detected in Ocm, Pvalb, Prkd1, Fbxo32, Nme2, and Sncg, which may play putative roles in the Ca(2+) buffering and survival regulation. …”
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“…The Ti(IV) complex [{Ph(2)P(BH(3))N}(2)C(6)H(4)Ti(NMe(2))(2)] (1) was obtained by the reaction between tetrakis-(dimethylamido)titanium(IV) and the protic aminophosphine–borane ligand [{Ph(2)P(BH(3))NH}(2)C(6)H(4)] (LH2) at ambient temperature. …”
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“…The group of tested compounds includes newly synthesized distyrylnaphthalene derivatives (DSNNs): a trimethylammonium derivative (DSNN-NMe(3)(+)), a phosphonate derivative (DSNN-P), a morpholine derivative (DSNN-Mor), a dihydroxyethylamine derivative (DSNN-DEA), a phosphonate potassium salt (DSNN-POK), an amino derivative (DSNN-NH(2)) and pyridinium derivative (DSNN-Py+). …”
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“…SpyCas9, SauCas9, SthCas9, NmeCas9, CjeCas9). This work presents a focused analysis of non-phage Acr proteins, demonstrating a role in horizontal gene transfer bolstered by broad spectrum CRISPR-Cas9 inhibition.…”
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“…We identified a genome-wide significant locus in IRAK3 (p = 3.57 × 10(–8), rs11465988, β = − 51.6, SE = 9.2) and a genome-wide significant gene-level association in NME7 (p = 1.73 × 10(–6)) for esketamine efficacy (i.e. percentage change in symptom severity score compared to baseline). …”
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“…Pre-coordination of the organic substrate to the reactive lithium amide as a key step in the amidation processes has been assessed, enabling the structural elucidation of the coordination adduct [{Li(NPh(2))(O[double bond, length as m-dash]CPh(NMe(2)))}(2)] (8) when toluene is employed as a solvent. …”
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“…Here, we report the syntheses of the two-dimensional metal–organic framework materials (H(2)NMe(2))(2)Nb(2)(Cl(2)dhbq)(3) and Mo(2)(Cl(2)dhbq)(3) (H(2)Cl(2)dhbq = 3,6-dichloro-2,5-dihydroxybenzoquinone), which feature mononuclear niobium or molybdenum metal nodes and are formed through reactions driven by metal-to-ligand electron transfer. …”
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“…In this work, we use Lewis acid–base interactions between Sb(III) and In(III) species formed at room temperature in situ from commercially available compounds (viz., InCl(3), Sb[NMe(2)](3) and a primary alkylamine) to obtain InSb adduct complexes. …”
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“…Using TENET, we identified and validated that Nme2 is a culture condition specific stem cell factor. …”
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“…When a difluoro complex LPt(IV)F(2)(Ar)(py) is treated with TMS–X (TMS = trimethylsilyl; X= NMe(2), SPh, OPh, CCPh) it also gives the corresponding products of the Ar–X coupling but without observable LPt(IV)F(py)(Ar)X intermediates. …”
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“…RESULTS: Four patients were found to have biallelic loss-of-function (LoF) variants in the following PCD-causing genes: CCDC114, DNAH5, HYDIN, and NME5. In four other patients, only one LoF variant was identified, while the remaining five patients did not have any LoF variants. …”
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“…Its molecular structure was determined by SC-XRD as Na(2)(5)·C(4)H(6)O(2), [PPN](2)(5)·C(5)H(12) (PPN = N(PPh(3))(2)](+)), [NBu(4)](2)(5) and [NMe(4)](2)(5) salts. 5 may be viewed as a dimer of 3 and, thus, it represents a rare case of polymerization isomerism (that is, two compounds having the same elemental composition but different molecular weights) in cluster chemistry. …”
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“…Functionally, miR-snaR associates with Ago proteins and targets NME1, a key metastasis inhibitor, contributing to snaR-A's role in promoting cancer cell migration. …”
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“…While the most acidic examples of such compounds have limited stability, the dicationic complexes with Carb(+) = 9-N-methylacridinium and Carb(+) = [C(Ar(N))(2)](+) (Ar(N) = p-(C(6)H(4))NMe(2)) are active as catalysts for the cycloisomerization of N-propargyl-4-fluorobenzamide, a substrate chosen to benchmark reactivity. …”
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“…This undergoes H/D exchange with D(2) at the (i)Pr groups, reacts with CO or NBD to return Rh(i) products, and reaction with H(3)B·NMe(3)/tert-butylethene results in a dehydrogenative borylation to form a complex that shows both a non-classical B–H⋯Rh 3c-2e agostic bond and a C–H⋯Rh anagostic interaction at the same metal centre.…”
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“…Grimme (MHG), who challenged the accuracy of our r (e) value for the N⋅⋅⋅Te distance in (C(6)F(5))Te(CH(2))(3)NMe(2) determined by gas electron diffraction (GED). …”
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“…GlcCer(d14:1/24:1), PE-NME (18:1/18:1), SM(d16:1/24:1), SM(d18:1/15:0), and SM(d18:1/16:1) can be used as potential serum markers for the diagnosis of PTC.…”
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“…Results: The MGRS model comprising 4 genes (TYMS, NME4, LDHA, and SMOX) was developed to classify patients into high-risk and low-risk groups. …”
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“…All polyelectrolytes are based on poly(allyl glycidyl ether) which has been modified by polymer-analogous reaction with anionic (-SO(3)Na), cationic (-NH(3)Cl or -NHMe(2)Cl) or zwitterionic groups (-NMe(2)(CH(2))(3)SO(3)). While the anionic polymer shows a very weak interaction, the zwitterionic polymer exhibits no interaction with BSA (pI = 4.7) under the applied pH = 7.4, ionic strength (I = 23–80 mM) and temperature conditions (T = 20–37 °C). …”
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“…Sericin improved epithelial cell proliferation by upregulating Nucleoside diphosphate kinase B (Nme2). Therefore, the therapeutic effect of sericin on psoriasis correlated with a reduced immune response and attenuated epidermal proliferation, making sericin a promising approach for skin psoriasis treatment.…”
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