Mostrando 41 - 60 Resultados de 647 Para Buscar '"NME"', tiempo de consulta: 0.33s Limitar resultados
  1. 41
    “…In vivo presence of NME2 at telomere ends was validated using independent methods and as further evidence we found intranuclear association of NME2 and the telomere repeat binding factor 2. …”
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  2. 42
    “…The cyclic compound 2,4-bis(dimethylamino)-1,3-diethylcyclodiphosphazane-2,4-dithione [systematic name: 2,4-bis(dimethylamino)-1,3-diethyl-1,3,2λ(5),4λ(5)-diazadiphosphetidine-2,4-dithione], C(8)H(22)N(4)P(2)S(2) or [EtNP(S)NMe(2)](2), is member of a class of mol­ecules that may be used, by virtue of their complexation properties, for the extraction of metals. …”
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  3. 43
  4. 44
    “…The first MSG, NM23 (non-metastatic clone 23, isoform H1) or now called NME1 (stands for non-metastatic) was identified some decades ago. …”
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  5. 45
    “…The influence of steric repulsion between the NMe(2) group and a second ortho-(peri-)substituent in the series of 1-dimethylaminonaphthalene and N,N-dimethylanilene ortho-oximes on the ease of the NMe(2) group’s intramolecular nucleophilic substitution is studied. …”
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  6. 46
  7. 47
    “…Coenzyme A (CoA) is a key cellular metabolite which participates in diverse metabolic pathways, regulation of gene expression and the antioxidant defense mechanism. Human NME1 (hNME1), which is a moonlighting protein, was identified as a major CoA-binding protein. …”
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  8. 48
  9. 49
    “…Here we show that the nucleoside diphosphate kinase gene Nme3 acts as a QTL on TRD. Reduction of the Nme3 dosage by gene targeting of the wild-type allele enhanced the transmission rate of the t-haplotype and phenocopied distorter function. …”
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  10. 50
    “…Recently, a large meta-analysis of five genome wide association studies (GWAS) identified a novel locus (rs2718058) adjacent to NME8 that played a preventive role in Alzheimer's disease (AD). …”
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  11. 51
    “…The ciliopathy-typical manifestations of NME3 depletion in two vertebrate in vivo models, the biochemical association of NME3 with validated NPHPs, and its localization to the basal body reveal a role for NME3 in ciliary function. …”
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  12. 52
    “…It has been previously reported that growing primed induced PSCs (iPSCs) in bFGF-depleted medium with NME7(AB) as the only added growth factor facilitates the regression of these cells to their naïve state. …”
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  13. 53
    “…Protein expression of Δ133p53α, Δ160p53α and ΔNp73α isoforms, NME1 and NME2, and N′ΔGLI1, GLI1FL, GLI2ΔN isoforms was elevated in tumour tissue, whereas ∆Np73β was downregulated. …”
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  14. 54
    “…We have identified a rare subpopulation of cells with markedly reduced expression of NME1 (NME1(LOW)) in human melanoma cell lines. To enable isolation of viable NME1(LOW) cells for phenotypic analysis by fluorescence-activated cell sorting (FACS), a CRISPR-Cas9-mediated approach was used to attach an EGFP coding module to the C-terminus of the endogenous NME1 gene in melanoma cell lines. …”
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  15. 55
    “…Our results, in each of these three steps of validation, confirm the prognostic capability of AHCY, DPYLS3, and NME1, and highlight their key role in neuroblastoma prognosis. …”
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  16. 56
    “…Mitochondria are involved in the regulation of cellular metabolism and the production of reactive oxygen species (ROS). NME/NM23 nuceloside diphosphate kinase 4 (NME4) gene is known to have the ability to supply nucleotide triphosphate and deoxynucleotide triphosphate for replication and transcription of mitochondria. …”
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  18. 58
    “…Herein, we utilized a bioinformatics approach to systematically identify genes whose expression is correlated with the metastasis suppressor function of NME1. This was accomplished through a search for genes that were regulated by NME1, but not by NME1 variants lacking metastasis suppressor activity. …”
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  20. 60
    “…And only Nme(2)Cas9‐Vegfa treatment during the early stage of CNV development reduced the CNV lesion area by 49.5%, compared to the negative control, while Nme(2)Cas9‐Hif1α or Nme(2)Cas9‐Vegfr2 treatment did not show therapeutic effect. …”
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