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121“…The metabolic clearance was the same for native LDL (17.1 ml h-1) and OL-NME-LDL complex (16.2 ml h-1). LDL incorporated OL-NME enhanced the anti-tumour activity against murine B16 melanoma model; this resulted from increased efficacy for OL-NME-LDL at doses equal to free 9-OH-NME (157 vs 76 of Increase Life Span (ILS) (%) values after intraperitoneal (i.p.) drug injection on i.p. implanted tumour model and 45 vs -2 ILS (%) values after intravenous drug injection on subcutaneous implanted tumour model). …”
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122por Depienne, Sébastien, Alvarez-Dorta, Dimitri, Croyal, Mikael, Temgoua, Ranil C. T., Charlier, Cathy, Deniaud, David, Mével, Mathieu, Boujtita, Mohammed, Gouin, Sébastien G.“…Phenylurazole (PhUr), N-methylphenylurazole (NMePhUr) and N-methylluminol (NMeLum) derivatives were described as tyrosine (Y) anchors after chemical or enzymatic oxidations. …”
Publicado 2021
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123“…Thus, our results suggest that efforts aimed at decreasing future NME use may be most effective if they target regions where NME use is already high, as well as the nearby regions. …”
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124por Aragão, Fernando Amâncio, Schäfer, Gabriel Santo, de Albuquerque, Carlos Eduardo, Vituri, Rogério Fonseca, de Azevedo, Fábio Mícolis, Bertolini, Gladson Ricardo Flor“…The assessment protocol was applied before the operation and two months after the operation, and the NME of the BF and VL muscles was obtained. RESULTS: There was no difference in the NME of the VL muscle from before to after the operation. …”
Publicado 2015
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125por Lob, Sibylle, Wise, Mark G, Siddiqui, Fakhar, Polis, Thales, DeRyke, C Andrew, Young, Katherine, Motyl, Mary, Sahm, Daniel F“…Lower IMI/REL-susceptibility of CR NME from Guatemala, Mexico, and Panama correlated with higher MBL rates among CR NME (37-93%), while IMI/REL activity against CR NME in countries with high KPC rates (≥80% in Argentina, Brazil, Colombia, Ecuador, and Puerto Rico) remained high (73-95% susceptible). …”
Publicado 2023
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126por Karlowsky, James A., Lob, Sibylle H., Siddiqui, Fakhar, Pavia, Jacqueline, DeRyke, C. Andrew, Young, Katherine, Motyl, Mary R., Sahm, Daniel F.“…IMR (96.9% susceptible), amikacin (95.9%), meropenem (90.7%), and imipenem (88.7%) were the most active agents against NME. Among piperacillin/tazobactam-nonsusceptible NME (n = 4124), 90.4% of isolates were IMR-susceptible (range by country, 97.2 [Chile] to 67.0% [Guatemala]) and among meropenem-nonsusceptible NME isolates (n = 1433), 74.0% were IMR-susceptible (94.1% [Puerto Rico] to 5.1% [Guatemala]). …”
Publicado 2023
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127por Szlosek, Robert, Ackermann, Matthias T., Marquardt, Christian, Seidl, Michael, Timoshkin, Alexey Y., Scheer, Manfred“…The coordination chemistry of only Lewis‐base (LB)‐stabilized pnictogenylboranes EH(2)BH(2)⋅NMe( 3 ) (E=P, As) towards Tl(I) salts has been studied. …”
Publicado 2022
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128por Ye, Daihua, Li, Tingxuan, Zheng, Zicheng, Zhang, Xizhou, Chen, Guangdeng, Yu, Haiying“…Average diameter of lateral roots was 0.17–19 mm for the ME and 0.18–0.21 mm for the NME. Greater acid phosphatase and phytase activities were observed in the ME grown under different levels of Po relative to the NME. …”
Publicado 2015
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129por Windsor, Rebecca, Stewart, Samuel D., Talboom, Joshua, Lewis, Candace, Naymik, Marcus, Piras, Ignazio S., Keller, Stefan, Borjesson, Dori L., Clark, Gary, Khanna, Chand, Huentelman, Matthew“…BACKGROUND: Necrotizing meningoencephalitis (NME, aka Pug dog encephalitis) is an inflammatory brain condition associated with advanced disease at initial presentation, rapid progression, and poor response to conventional immunomodulatory therapy. …”
Publicado 2021
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130por de Faria Castro Fleury, Eduardo, Castro, Caio, do Amaral, Mario Sergio Campos, Roveda Junior, Décio“…RATIONALE AND OBJECTIVES: According to the Breast Imaging and Reporting Data System (BI-RADS), one of the main limitations of MRI is diagnosing the non-mass enhancement (NME). The NME lesion is challenging since it is unique to the MRI lexicon. …”
Publicado 2022
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131por Windsor, Rebecca, Stewart, Samuel, Schmidt, Jessica, Mosqueda, Mario, Piras, Ignazio, Keller, Stefan M., Steinmetz, Briana, Borjesson, Dori L., Huentelman, Matthew, Khanna, Chand“…HYPOTHESIS/OBJECTIVE: Pug dogs at genetic risk for NME might manifest neurological abnormalities before developing pathognomonic clinical signs of NME. …”
Publicado 2022
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132por Misan, Natalia, Michalak, Sławomir, Rzymski, Piotr, Poniedziałek, Barbara, Kapska, Katarzyna, Osztynowicz, Krystyna, Ropacka-Lesiak, Mariola“…The serum NME1 levels and placental CLN4 expression were predictive markers of IVH in the FGR group. …”
Publicado 2022
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133por Ruamps, Mirko, Bastin, Stéphanie, Rechignat, Lionel, Sournia-Saquet, Alix, Vendier, Laure, Lugan, Noël, Mouesca, Jean-Marie, Valyaev, Dmitry A., Maurel, Vincent, César, Vincent“…While the complexes [CuCl(IMes((NMe2)2))], [RhCl(COD)(IMes((NMe2)2))], and [FeCp(CO)(2) (IMes((NMe2)2))](BF(4)) exhibit two oxidation waves, the first oxidation wave is fully reversible but only for the first complex the second oxidation wave is reversible. …”
Publicado 2022
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134“…Necrolytic migratory erythema (NME) is usually associated with paraneoplastic syndrome caused by functional pancreatic neuroendocrine tumor (PNET). …”
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135“…Interestingly, only Pug dogs with necrotizing meningoencephalitis (NME) showed elevated serum GFAP concentrations (<0.01 to 1.14 ng/ml), while other breeds of dogs with NME did not. …”
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136“…In early drug development advanced imaging techniques can help with progressing new molecular entities (NME) to subsequent phases of drug development and thus reduce attrition. …”
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137por Cross, Penelope J., Heyes, Logan C., Zhang, Shiwen, Nazmi, Ali Reza, Parker, Emily J.“…Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (NmeDAH7PS) adopts a homotetrameric structure consisting of an extensive and a less extensive interface. …”
Publicado 2016
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138por Zhu, Ke-Wei, Chen, Peng, Zhang, Dao-Yu, Yan, Han, Liu, Han, Cen, Li-Na, Liu, Yan-Ling, Cao, Shan, Zhou, Gan, Zeng, Hui, Chen, Shu-Ping, Zhao, Xie-Lan, Chen, Xiao-Ping“…Three SNPs (NME1 rs3760468, NME2 rs3744660, and RRM1 rs183484) were associated with worse OS in AML patients. …”
Publicado 2018
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139“…Here we present a propeller-like squaraine dye SQ-NMe(2) decorated with four peripheral dimethylamines acting as electron donors and spatial obstacles. …”
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140por Schrauwen, Isabelle, Barber, Renee M., Schatzberg, Scott J., Siniard, Ashley L., Corneveaux, Jason J., Porter, Brian F., Vernau, Karen M., Keesler, Rebekah I., Matiasek, Kaspar, Flegel, Thomas, Miller, Andrew D., Southard, Teresa, Mariani, Christopher L., Johnson, Gayle C., Huentelman, Matthew J.“…Necrotizing meningoencephalitis (NME) affects toy and small breed dogs causing progressive, often fatal, inflammation and necrosis in the brain. …”
Publicado 2014
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