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201por Spencer, Katie, Velikova, Galina, Henry, Ann, Westhoff, Paulien, Hall, Pe ter, van der Linden, Yvette M.“…This study assesses the use of NPR as an outcome measure after palliative radiation therapy for bone metastases. …”
Publicado 2019
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202“…Furthermore, a thermo-mechanical coupling analysis model of the NPR spacer was established and the deformation and force output characteristics of the NPR spacer were studied and experimentally verified. …”
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203“…Since nuclear translocation of NPR1-GR requires dexamethasone, we were able to control NPR1-dependent transcription and identify direct transcriptional targets of NPR1. …”
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204por Cudalbeanu, Mihaela, Peitinho, David, Silva, Francisco, Marques, Rosa, Pinheiro, Teresa, Ferreira, Ana C., Marques, Fernanda, Paulo, António, Soeiro, Catarina F., Sousa, Sílvia Andreia, Leitão, Jorge Humberto, Tăbăcaru, Aurel, Avramescu, Sorin Marius, Dinica, Rodica Mihaela, Campello, Maria Paula Cabral“…Root extracts from Danube Delta Nymphaea alba were used to prepare gold nanoparticles (AuNPR(n)) by reducing HAuCl(4) at different pHs (6.4–8.4) using ultrasonic irradiation: an easy, cheap, eco-friendly and green approach. …”
Publicado 2021
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205por Cronjé, Héléne T., Karhunen, Ville, Hovingh, G. Kees, Coppieters, Ken, Lagerstedt, Jens O., Nyberg, Michael, Gill, Dipender“…METHODS: Instrumental variables mimicking the effects of pharmacological intervention on CNP were identified as uncorrelated genetic variants located in the genes coding for its primary receptors, natriuretic peptide receptors-2 and 3 (NPR2 and NPR3), that associated with height. We performed MR and colocalization analyses to investigate the effects of NPR2 signalling and NPR3 function on CVD outcomes and risk factors. …”
Publicado 2023
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206por Weng, Yung-Jin, Huang, Jen-Ching, Chen, Yueh-Yang, Hsu, Shao-Teng, Zhang, Zu-Rong“…To dynamically stretch molds and control the microstructural shape, the proposal is committed to using the NPR structure as a regulatory mechanism. The NPR structural and dynamic parallel NPR-molds to control microstructure mold-cores were simulated and analyzed. …”
Publicado 2021
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207por Chang, Andy J, Chronis, Nikolas, Karow, David S, Marletta, Michael A, Bargmann, Cornelia I“…C. elegans detects oxygen through soluble guanylate cyclase homologs (sGCs) and responds to it differently depending on the activity of the neuropeptide receptor NPR-1: npr-1(lf) and naturally isolated npr-1(215F) animals avoid high oxygen and aggregate in the presence of food; npr-1(215V) animals do not. …”
Publicado 2006
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208“…The Kaplan–Meier (K–M) survival along with the univariate and multivariate Cox analyses was used to examine the prognostic value of NPR in AAD. In addition, nomograms were constructed by combining NPR, age, Stanford typing, and treatment methods. …”
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209por Kim, Tae-Young, Park, No-June, Jegal, Hyun, Paik, Jin-Hyub, Choi, Sangho, Kim, Su-Nam, Yang, Min Hye“…The chemical composition of NPR extract was analyzed using an HPLC-PDA system. …”
Publicado 2023
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210por Mahinrad, Simin, Bulk, Marjolein, van der Velpen, Isabelle, Mahfouz, Ahmed, van Roon-Mom, Willeke, Fedarko, Neal, Yasar, Sevil, Sabayan, Behnam, van Heemst, Diana, van der Weerd, Louise“…Our results showed that NP and NPR genes were ubiquitously expressed throughout the brain in healthy humans. …”
Publicado 2018
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211por Subramanian, Umadevi, Ramasamy, Chandramohan, Ramachandran, Samivel, Oakes, Joshua M., Gardner, Jason D., Pandey, Kailash N.“…The objective of this study was to determine the mechanisms regulating the development of cardiac fibrosis and dysfunction in Npr1 mutant mice. Npr1 knockout (Npr1(−/−), 0-copy), heterozygous (Npr1(+/−), 1-copy), and wild-type (Npr1(+/+), 2-copy) mice were treated with the transforming growth factor (TGF)-β1 receptor (TGF-β1R) antagonist GW788388 (2 µg/g body weight/day; ip) for 28 days. …”
Publicado 2022
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212Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor modelpor Peake, Nicholas, Su, Nyan, Ramachandran, Manoj, Achan, Pramod, Salter, Donald M, Bader, Dan L, Moyes, Amie J, Hobbs, Adrian J, Chowdhury, Tina T“…In separate experiments, constructs were cultured under free-swelling conditions or subjected to dynamic compression with CNP, interleukin-1β (IL-1β), the Npr2 antagonist P19 or the Npr3 agonist cANF(4-23). …”
Publicado 2013
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213por Fan, Mingzhen, Miao, Yuyang, Yan, Yutong, Zhu, Kunyuan, Zhao, Xiaoe, Pan, Menghao, Ma, Baohua, Wei, Qiang“…The results showed that goat mammary gland expressed NPR-B, but not CNP. The expression and secretion of S100A7 in goat MECs were obviously induced by CNP/NPR-B signaling pathway. …”
Publicado 2022
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214“…The N-propionylated group B meningococcal polysaccharide (NPrGBMP) mimics a unique protective epitope on the surface of group B meningococci (GBM) and Escherichia coli K1. …”
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215Taipan Natriuretic Peptides Are Potent and Selective Agonists for the Natriuretic Peptide Receptor Apor Vink, Simone, Akondi, Kalyana Bharati, Jin, Jean, Poth, Kim, Torres, Allan M., Kuchel, Philip W., Burke, Sandra L., Head, Geoffrey A., Alewood, Paul F.“…We now describe several taipan (Oxyuranus microlepidotus) natriuretic peptides TNPa-e which stimulated cGMP production through the natriuretic peptide receptor A (NPR-A) with higher potencies for the rat NPR-A (rNPR-A) over human NPR-A (hNPR-A). …”
Publicado 2023
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216por Chen, Huan, Li, Min, Qi, Guang, Zhao, Ming, Liu, Longyu, Zhang, Jingyi, Chen, Gongyou, Wang, Daowen, Liu, Fengquan, Fu, Zheng Qing“…We further demonstrate that EDS1 stabilizes NPR1 protein and NPR1 transcriptionally up-regulates EDS1. …”
Publicado 2021
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217por Allaoui, Hinda, Rached, Nedra, Marrakchi, Naziha, Cherif, Ameur, Mosbah, Amor, Messadi, Erij“…We found that L2 exhibited higher affinity for all human NPRs compared to BNP, with a rank preference for NPR-A > NPR-C > NPR-B. Moreover, L2 affinity for human NPR-A and NPR-C was higher in other species. …”
Publicado 2022
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218por Shuhaibar, Leia C., Kaci, Nabil, Egbert, Jeremy R., Horville, Thibault, Loisay, Léa, Vigone, Giulia, Uliasz, Tracy F., Dambroise, Emilie, Swingle, Mark R., Honkanen, Richard E., Duplan, Martin Biosse, Jaffe, Laurinda A., Legeai-Mallet, Laurence“…Here, because FGFR3 signaling decreases NPR2 activity by dephosphorylating the NPR2 protein, we tested whether a phosphatase inhibitor (LB-100) could enhance BMN-111–stimulated bone growth in ACH. …”
Publicado 2021
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219“…In this study, we address the problem of compliance mismatch by designing and developing a 3D tubular construct that has a negative Poisson’s ratio ν(xy) (NPR). NPR constructs have the unique ability to expand transversely when pulled axially, thereby resulting in a highly-compliant tubular construct. …”
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220por Neinast, Michael D., Frank, Aaron P., Zechner, Juliet F., Li, Quanlin, Vishvanath, Lavanya, Palmer, Biff F., Aguirre, Vincent, Gupta, Rana K., Clegg, Deborah J.“…RESULTS: RYGB and calorie restriction induced similar weight loss and improved glucose metabolism without decreasing food intake. β3-adrenergic receptor expression increased in gonadal adipose tissue, in addition to Nppb (BNP), and NP receptors, Npr1, and Npr2. The ratio of Npr1:Npr3 and Npr2:Npr3 increased in RYGB, but not WM-SO groups. …”
Publicado 2015
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