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221por Tang, Haipei, Liu, Yun, Li, Jianzhen, Yin, Yike, Li, Gaofei, Chen, Yu, Li, Shuisheng, Zhang, Yong, Lin, Haoran, Liu, Xiaochun, Cheng, Christopher H. K.“…This conclusion is based on the following results: (1) the expression level of npr peaks at the full-grown stage of the follicles; (2) the expression of npr is stimulated by LH signaling in vitro and in vivo; and (3) the npr null females are infertile due to ovulation defects. …”
Publicado 2016
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222“…PURPOSE: This study investigated the role of natriuretic peptide receptor 2 (NPR2) on cell proliferation and testosterone secretion in mouse Leydig cells. …”
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223“…Background: The Swedish National Patient Registry (NPR) is a nationwide registry that is used extensively for epidemiological research. …”
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224por Murley, Chantelle, Friberg, Emilie, Hillert, Jan, Alexanderson, Kristina, Yang, Fei“…We aimed to estimate the validity of multiple sclerosis (MS) diagnoses registered in the Swedish National Patient Register (NPR) by two sequential register-based case-definition algorithms. …”
Publicado 2019
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225por Zhang, Xiangyi, Pan, Yi-Hsuan, Chen, Ying, Pan, Chenhua, Ma, Ji, Yuan, Chonggang, Yu, Guohua, Ma, Jiyan“…To investigate how the N-terminal polybasic region of PrP (NPR) influences the PrP(C)-to-PrP(Sc) conversion, we analyzed two PrP mutants: ΔN6 (deletion of all six amino acids in NPR) and Met4-1 (replacement of four positively charged amino acids in NPR with methionine). …”
Publicado 2021
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226por Mackasey, Martin, Egom, Emmanuel E., Jansen, Hailey J., Hua, Rui, Moghtadaei, Motahareh, Liu, Yingjie, Kaur, Jaspreet, McRae, Megan D., Bogachev, Oleg, Rafferty, Sara A., Ray, Gibanananda, Kirkby, Adam W., Rose, Robert A.“…Natriuretic peptide(s) (NP) are cardioprotective hormones whose effects can be mediated partly by the NP receptor C (NPR-C). We investigated the role of NPR-C in angiotensin II (Ang II)-mediated SAN disease in mice. …”
Publicado 2018
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227por Panayiotou, Catherine M, Baliga, Reshma, Stidwill, Raymond, Taylor, Valerie, Singer, Mervyn, Hobbs, Adrian J“…Since both NO and natriuretic peptides play important roles in cardiovascular homeostasis via activation of guanylate cyclase-linked receptors, we used mice lacking natriuretic peptide receptor (NPR)-A (NPR1) to establish if natriuretic peptides contribute to the cardiovascular dysfunction present in endotoxic shock. …”
Publicado 2010
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228por Miura, Kohji, Namba, Noriyuki, Fujiwara, Makoto, Ohata, Yasuhisa, Ishida, Hidekazu, Kitaoka, Taichi, Kubota, Takuo, Hirai, Haruhiko, Higuchi, Chikahisa, Tsumaki, Noriyuki, Yoshikawa, Hideki, Sakai, Norio, Michigami, Toshimi, Ozono, Keiichi“…We describe a three-generation family with tall stature, scoliosis and macrodactyly of the great toes and a heterozygous p.Val883Met mutation in Npr2, the gene that encodes the CNP receptor NPR2 (natriuretic peptide receptor 2). …”
Publicado 2012
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229por Khan, Saadullah, Ali, Raja Hussain, Abbasi, Sanaullah, Nawaz, Muhammad, Muhammad, Noor, Ahmad, Wasim“…Mutations in the gene NPR2 have been shown to cause acromesomelic dysplasia-type Maroteaux (AMDM), an autosomal recessive skeletal disproportionate dwarfism disorder in humans. …”
Publicado 2012
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230por Smith, Julie, Fahrenkrug, Jan, Jørgensen, Henrik L, Christoffersen, Christina, Goetze, Jens P“…TG concentrations in serum peaked in the active dark period (P=0.003). In conclusion, NPR-A and NPR-C gene expression is associated with the expression of clock genes in white adipose tissue. …”
Publicado 2015
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231“…The cytoprotective effects of CNP are mediated in part via the G(i)-coupled natriuretic peptide receptor (NPR)3. As GPCRs are well-known to control cell proliferation, we investigated if NPR3 activation underlies effects of CNP on endothelial and vascular smooth muscle cell mitogenesis. …”
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232“…The deduced Npr protein sequences from the retrieved npr genes also showed that most of the Npr sequences used in this study were closely related to those of the genus Bacillus, with similarities ranging from 61% to 100%. …”
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233por Rizzuto, Debora, Feldman, Adina L., Karlsson, Ida K., Dahl Aslan, Anna K., Gatz, Margaret, Pedersen, Nancy L.“…RESULTS: Barely half of the dementia cases were ever detected by NPR or CDR. Using data from longitudinal studies we estimated that a record with a dementia diagnosis appears in the NPR on average 5.5 years after first diagnosis. …”
Publicado 2018
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234por Khan, Muhammad Saad Shoaib, Islam, Faisal, Chen, Huan, Chang, Ming, Wang, Daowen, Liu, Fengquan, Fu, Zheng Qing, Chen, Jian“…Recent findings show that Enhanced Disease Susceptibility 1 (EDS1) also functions as a transcriptional coactivator and stimulates the expression of PR1 in the presence of NPR1 and SA. Furthermore, EDS1 stabilizes NPR1 protein level, while NPR1 sustains EDS1 expression during pathogenic infection. …”
Publicado 2022
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235“…There was no difference in PROMs between PR and NPR in five studies, whereas PR was found to be superior to NPR in one study. …”
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236“…Previous studies have shown that inflammation is a major pathological feature of ICH, and the neutrophil-to-platelet ratio (NPR) is a marker of systemic inflammation. Therefore, we aimed to assess the association between the NPR and HE in ICH patients. …”
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237por Zhang, Junzhe, Lei, Wenxue, Meng, Yixuan, Zhou, Chengqian, Zhang, Baihong, Yuan, Jun, Wang, Min, Xu, Dongqing, Meng, Xiangchun, Chen, Wenli“…Here, we demonstrated that NPR1-GFP protein expression was observed from the 12th hour to the 10th day after infiltrating AuNPs-PEI-pNPR1 (Arabidopsis thaliana nonexpressor of pathogenesis-related gene 1)-GFP. …”
Publicado 2022
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238por Tian, Li, Yang, Jinshan, You, Xiao, Wang, Mengmeng, Ren, Xiaoyin, Zhang, Xiangyu, Dong, Shaoming“…Graphene metamaterials with a radial-like structure and negative Poisson’s ratio (NPR) were assembled using a unique centripetal freezing technique. …”
Publicado 2022
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239por Abildgaard, Niels, Freilich, Jonatan, Anttila, Pekka, Bent-Ennakhil, Nawal, Ma, Yuanjun, Lassenius, Mariann, Ørstavik, Sigurd, Toppila, Iiro, Waage, Anders, Turesson, Ingemar, Hansson, Markus“…Patients newly diagnosed with MM who received MM-specific treatment were included. PDR/NPR treatment records were used to assess incident NPR cases. …”
Publicado 2023
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240“…Furthermore, analysis of npr1-1 and the tga1-1 tga4-1 npr1-1 triple mutant indicates that clade I TGA factors act substantially independent of NPR1 in mediating disease resistance against these strains of P. syringae. …”
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