“…Isatin, an antagonist of human natriuretic peptide receptors (NPR), prevents this effect. Furthermore, the human NPR-C receptor agonist cANF(4-23) mimics the effects of natriuretic peptides on P. aeruginosa, while sANP, the NPR-A receptor agonist, appears to be weakly active. …”
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“…The aim of this study was to investigate the therapeutic effects of gene transduction using caNPR2 for pulmonary arterial hypertension (PAH). …”
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“…A cGMP signaling cascade composed of C-type natriuretic peptide, the guanylyl cyclase receptor Npr2 and cGMP-dependent protein kinase I (cGKI) controls the bifurcation of sensory axons upon entering the spinal cord during embryonic development. …”
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“…The most common systematic error was the registration of re-admissions as acute fractures in the NPR (84% of all erroneous registrations). With this knowledge, an adjustment model for NPR data was constructed to increase the accuracy of fracture registrations (PPV 92%) without excluding valid registrations. …”
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“…This interaction was abolished in loss-of-function alleles of NPR1. Interactions between βCAs and both NRB4 and NPR1 were also detected in planta, with evidence for a triple interaction, NRB4-βCA1-NPR1. …”
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“…For problems with less complex constraints, the NPR model can also be solved using exact methods such as CPLEX. …”
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“…The effects of the geometric parameters on the equivalent stiffness, buckling, natural frequency and NPR effect were also investigated. To increase the NPR of SP-PSC, the material of facesheet was changed from isotropic material to unidirectional CFPR material, and the influence of the material anisotropy on the NPR effect of SP-PSC was investigated. …”
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“…The “Cr–N 1-2-3” complex was prepared from NCr(NHPh)(NPr(i)(2))(2), which exists as this nitrido–amido tautomer, rather than the bis(imido) Cr(NH)(NPh)(NPr(i)(2))(2). …”
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“…The GATOR1/SEACIT complex consisting of Iml1-Npr2-Npr3 inhibits Target of Rapamycin Complex 1 (TORC1) in response to amino acid insufficiency. …”
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“…Remarkably, the AlP monolayer possesses a giant NPR of −1.779, by far the largest NPR in 2D materials. …”
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“…Education and training were positively associated with the NPR COVID‐19 score. Nurses' characteristics, such as seniority, job category and educational level, were entered into the NPR COVID‐19 regression model, and seniority (≤5 years) showed the strongest negative association with NPR COVID‐19 scores (standard coefficient = −0.20). …”
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“…However, combining sid2 and npr1 in the sid2npr1 double mutant compromises resistance to Xcc, suggesting genetic interactions likely exist between SID2 and NPR1 in the non-host resistance against Xcc in Arabidopsis. …”
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“…The study showed that in npr1 (GFP-ATG8a), AvrRpt2 was more effective at inducing the production of autophagosome and autophagy flux than that in GFP-ATG8a. …”
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“…However, the mode of SA perception is unclear. NPR1 protein has been shown to bind SA. Nevertheless, NPR1 action requires upstream regulatory events (such as a change in cell redox status). …”
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“…OBJECTIVES: In this study we aimed to decipher changes in cell growth and the transcriptome in an immortalized human normal prostate epithelial cell line (NPrEC) following exposure to low-dose Cd. METHODS: Synchronized NPrEC cells were exposed to different doses of Cd and assayed for cell viability and cell-cycle progression. …”
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“…We adapted this protocol to a high-throughput format and identified six npr1 suppressors that accumulated lower levels of SA than npr1 upon pathogen infection. …”
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“…The aim was to validate diagnoses of IBD among patients aged 50+ years in the Danish National Patient Registry (NPR) by comparison with patient medical records. …”
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“…The cytoplasmic domains of both NPR1 and NPR2 display a guanylate cyclase activity that catalyzes the formation of cyclic GMP. …”
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“…The nprR was then found to be required for Bacillus anthracis sporulation. …”
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“…According to the NPR, the proportion of false positives and false negatives was 3.5% and 6.8%, respectively. …”
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