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261Vascular Relaxation Induced by C-Type Natriuretic Peptide Involves the Ca(2+)/NO-Synthase/NO Pathwaypor Andrade, Fernanda A., Restini, Carolina B. A., Grando, Marcella D., Ramalho, Leandra N. Z., Bendhack, Lusiane M.“…We hypothesized that NO produced by the endothelial NO-synthase (NOS-3) contributes to the relaxation induced by CNP in isolated rat aorta via activation of endothelial NPR-C receptor. Therefore, the aim of this study was to investigate the putative contribution of NO through NPR-C activation in the CNP induced relaxation in isolated conductance artery. …”
Publicado 2014
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262por Lin, Xue-Lian, Tang, Xu-Dong, Cai, Zheng-Xu, Wang, Feng-Yun, Li, Ping, Sui, Hua, Guo, Hui-Shu“…Taken together, these results indicate that the up-regulation of the NPs/NPR-C and NPs/NPR-A, B/cGMP signaling pathways may be involved in depression-induced loss of gastric ICC.…”
Publicado 2016
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263por Juras, Anna, Krzewińska, Maja, Nikitin, Alexey G., Ehler, Edvard, Chyleński, Maciej, Łukasik, Sylwia, Krenz-Niedbała, Marta, Sinika, Vitaly, Piontek, Janusz, Ivanova, Svetlana, Dabert, Miroslawa, Götherström, Anders“…To fill this gap, we analyzed ancient mitochondrial DNA (mtDNA) from Scythians of the North Pontic Region (NPR) and successfully retrieved 19 whole mtDNA genomes. …”
Publicado 2017
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264por Ren, Meixia, Ng, Fu Liang, Warren, Helen R, Witkowska, Kate, Baron, Michael, Jia, Zhilong, Cabrera, Claudia, Zhang, Ruoxin, Mifsud, Borbala, Munroe, Patricia B, Xiao, Qingzhong, Townsend-Nicholson, Andrea, Hobbs, Adrian J, Ye, Shu, Caulfield, Mark J“…Genome-wide association studies have identified several genetic variants at the NPR3 locus associated with BP, but the functional impact of these variants remains to be determined. …”
Publicado 2018
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265por He, Weilei, Ruan, Yiting, Yuan, Chengxiang, Cheng, Qianqian, Cheng, Haoran, Zeng, Yaying, Chen, Yunbin, Huang, Guiqian, Chen, Huijun, He, Jincai“…NPR (>39.9) was independently associated with PH (OR = 2.641, 95% CI: 1.308–5.342, P = 0.007). …”
Publicado 2019
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266por Vasques, Gabriela, Andrade, Nathalia, Funari, Mariana, Nishi, Mirian, Quedas, Elisangela, Mendonca, Berenice, Jorge, Alexander“…Variants in NPR2 and IHH genes were identified in children with isolated short stature or with nonspecific skeletal abnormalities. …”
Publicado 2019
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267“…Opioid agonists activated heterologously expressed NPR-17, as did at least one NLP-24 peptide. Worms lacking the ASI neurons, which express npr-17, did not response to naloxone. …”
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268“…The maximum magnitude of out-of-plane NPR is identified in the case of (20 (F)/20 (C)/−20 (C)/20 (C)) (S) laminate as well. …”
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269por Guo, Chunxia, Zhao, Dong, Liu, Zhanli, Ding, Qian, Gao, Haoqiang, Yan, Qun, Sun, Yongtao, Ren, Fuguang“…In this paper, the quasi-static and dynamic compression tests of three kinds of 3D-printed NPR convex–concave honeycomb tubes are carried out. …”
Publicado 2021
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270por Li, Xiaowen, Qiang, Xiaobin, Gong, Zhenhao, Zhang, Yubo, Gong, Penglai, Chen, Lang“…Negative Poisson's ratio (NPR) materials are functional and mechanical metamaterials that shrink (expand) longitudinally after being compressed (stretched) laterally. …”
Publicado 2021
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271por Buttgereit, Jens, Shanks, Julia, Li, Dan, Hao, Guoliang, Athwal, Arvinder, Langenickel, Thomas H., Wright, Hannah, da Costa Goncalves, Andrey C., Monti, Jan, Plehm, Ralph, Popova, Elena, Qadri, Fatimunnisa, Lapidus, Irina, Ryan, Brent, Özcelik, Cemil, Paterson, David J., Bader, Michael, Herring, Neil“…Immunohistochemistry demonstrated co-staining of NPR-B with tyrosine hydroxylase in stellate ganglia neurons. …”
Publicado 2016
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272por Park, Jung-Kyu, Kim, Kun Woo, Kim, Hyun Joo, Choi, Seon Young, Son, Kuk Hui, Lee, Jin Woo“…Briefly, a skin scaffold with the NPR effect was fabricated by creating a fine pattern through 3D printing. …”
Publicado 2023
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273“…The results show that the alternative arrangement of S- and Z-twisted 4-ply auxetic yarns in a woven fabric can generate a higher negative Poisson’s ratio (NPR) of the fabric. While the higher single stiff yarn modulus of auxetic yarn can result in greater NPR behavior, finer soft auxetic yarn does not necessarily generate such an effect. …”
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274“…Inspired by the buckled pentagonal iso-structures that often expose NPR, we employ state-of-the-art first-principles density functional theory calculations and analyses to predict a new 2D metallic ternary auxetic penta-phosphorus boron nitride (p-PBN) with a high value of NPR. …”
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275por Dozot, Marie, Poncet, Sandrine, Nicolas, Cécile, Copin, Richard, Bouraoui, Houda, Mazé, Alain, Deutscher, Josef, De Bolle, Xavier, Letesson, Jean-Jacques“…The intracellular pathogens Brucella spp. possess four PTS proteins (EI(Ntr), NPr, EIIA(Ntr) and an EIIA of the mannose family) but no PTS permease suggesting that this PTS might serve only regulatory functions. …”
Publicado 2010
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276por Henesy, Michelle B., Britain, Andrea L., Zhu, Bing, Amable, Lauren, Honkanen, Richard E., Corbin, Jackie D., Francis, Sharron H., Rich, Thomas C.“…However, little is known about the molecular mechanisms that underlie desensitization of natriuretic peptide receptors, including natriuretic peptide receptor-A (NPR-A). Here we report that calcineurin (protein phosphatase 2B, PP2B, PPP3C) regulates homologous desensitization of NPR-A in murine Leydig tumor (MA-10) cells. …”
Publicado 2012
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277por Ochoa Cordero, Manuel, Meza Herrera, César A., Vázquez García, Juan M., Stewart, Caroline A., Rosales Nieto, César A., Ochoa Alfaro, Ana E., Purvis, Ian W., Cuevas Reyes, Venancio, Lee Rangel, Héctor A., Martin, Graeme B.“…Following lambing, FI increased in PRG ewes (p < 0.001) to double the values in NPR ewes. PRG reduced WP (p < 0.001); in PR3, WP was lower than for both PR1 and NPR (p < 0.001). …”
Publicado 2019
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278por Arden, Sam, Morelli, Ben, Schoen, Mary, Cashman, Sarah, Jahne, Michael, Ma, Xin (Cissy), Garland, Jay“…Onsite non-potable reuse (NPR) is being increasingly considered as a viable option to address water scarcity and infrastructure challenges, particularly at the building scale. …”
Publicado 2020
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279“…The weighted ISI of NPR with leakage was correlated with MCP-1, IL-8, IL-6, PlGF, and VEGF-A levels, while the non-weighted ISI of NPR with leakage was correlated with IL-8 and IL-6 levels. …”
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280por Fedchenko, Maria, Mandalenakis, Zacharias, Hultsberg-Olsson, Görel, Dellborg, Helena, Eriksson, Peter, Dellborg, Mikael“…The National Swedish Patient Register (NPR) is widely used in epidemiological studies; however, MI diagnoses specifically in patients with CHD have never been validated in the NPR. …”
Publicado 2020
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