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  1. 1241
    “…RUS improved survival rates and arterial structure, suppressed proinflammatory cytokines, down-regulated miR-146a-5p, and up-regulated NPR2 and SSH1 in septic mice. In HUVECs, RUS increased cell viability, suppressed apoptosis, inhibited inflammation, downregulated miR-146a-5p, and increased NRP2 and SSH1 levels. …”
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    Ruscogenin Attenuates Lipopolysaccharide-Induced Septic Vascular Endothelial Dysfunction by Modulating the miR-146a-5p/NRP2/SSH1 Axis
  2. 1242
    por Hakami, Tahir
    Publicado 2022
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    Clinical characteristics and treatment outcomes of patients with newly diagnosed schizophrenia: A 4‐year single‐center experience in Saudi Arabia
  3. 1243
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    Multisectoral actions of mental health during the COVID‐19 pandemic in Mazandaran province of Iran
  4. 1244
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    A 12‐session relapse prevention program vs psychoeducation in the treatment of Japanese alcoholic patients: A randomized controlled trial
  5. 1245
    “…Results: White blood cell count (WBC), neutrophil count (NEU), red cell volume distribution width (RDW), NLR, Platelet to lymphocyte ratio (PLR), neutrophil-to-platelet ratio (NPR), and SII were significantly higher in the severe groups than in the non-severe group (p < 0.01).Conversely, the severe group had a markedly decreased lymphocyte count, basophil (Baso#) count, red blood cell count (RBC), Hemoglobin (HGB), hematocrit (HCT), and lymphocyte-to-monocyte ratio (LMR) (P < 0.01).ROC curve analysis showed the AUC, optimal cut-off value, sensitivity, specificity of NLR and SII to early predict severe-patients with COVID-19 were 0.867, 7.25, 70.83%, 92.21% and 0.860, 887.20, 81.25%, 81.82%, respectively. …”
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    Predictive Value of Systemic Immune-Inflammation index and Neutrophil-to-Lymphocyte Ratio in Patients with Severe COVID-19
  6. 1246
    “…Eleven of 18 (61%) families revealed explanatory variants, including 7 single-nucleotide variant alleles and 3 copy number variants (CNVs), at previously reported “disease trait associated loci”: BHLHA9, GLI3, HOXD cluster, HOXD13, NPR2, and WNT10B. Breakpoint junction analyses for all three CNV alleles revealed mutational signatures consistent with microhomology-mediated break-induced replication, a mechanism facilitated by Alu/Alu-mediated rearrangement. …”
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    Developmental genomics of limb malformations: Allelic series in association with gene dosage effects contribute to the clinical variability
  7. 1247
    “…In addition, we find that Ler/Kas-2 incompatibility is dependent on NPR1 (NONEXPRESSER OF PR GENES 1) and nitric oxide production. …”
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    Ammonium and nitric oxide condition the establishment of Arabidopsis Ler/Kas-2 immune-related hybrid incompatibility
  8. 1248
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    Development and acceptability of a decision aid for major depressive disorder considering discontinuation of antidepressant treatment after remission
  9. 1249
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    Prolonged extrapyramidal symptoms induced by long‐term, intermittent administration of low‐dose olanzapine along with metoclopramide for emesis: A case report
  10. 1250
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    Residual effects of low dose of suvorexant, zolpidem, and ramelteon in healthy elderly subjects: A randomized double‐blind study
  11. 1251
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    Anodal transcranial direct current stimulation sustainably increases EEG alpha activity in patients with schizophrenia
  12. 1252
    “…We also found that TYLCV levels were affected in SlNPR1 and SlCOI1 silenced plants. Interestingly, compared to the mock treated samples, SA signaling was hyper-activated in SlCOI1 silenced plants which resulted in a significant reduction in viral titer, whereas in SINPR1 silencing tomato plants, there was a 19-fold increase in viral load. …”
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    Physiological and transcriptomic analyses revealed gene networks involved in heightened resistance against tomato yellow leaf curl virus infection in salicylic acid and jasmonic acid treated tomato plants
  13. 1253
    “…In this manuscript, we utilized hydroponics-medium to assess the effect of controlled application of micronutrients, including iron (Fe), manganese (Mn), and zinc (Zn) on the expression of important IR genes (PR1, PR5, and NPR1 from salicylic acid (SA) pathway, and VSP, PDF, and LOX genes from jasmonic acid (JA) pathway) in watermelon seedlings upon inoculation with either FON or RKN or both. …”
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    Micronutrients Affect Expression of Induced Resistance Genes in Hydroponically Grown Watermelon against Fusarium oxysporum f. sp. niveum and Meloidogyne incognita
  14. 1254
    “…Most of the findings were in genes associated with the growth plate differentiation: IHH (n  = 4), SHOX (n  = 3), FGFR3 (n  = 2), NPR2 (n  = 2), ACAN (n  = 2), and COL2A1 (n  = 1) or involved in the RAS/MAPK pathway: NF1 (n  = 2), PTPN11 (n  = 1), CBL (n  = 1), and BRAF (n  = 1). …”
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    Diagnostic yield of a multigene sequencing approach in children classified as idiopathic short stature
  15. 1255
    “…Several defense genes, including WRKY28 and PTI5 of PAMP-triggered immunity (PTI), UDP and UDP1 of effector-triggered immunity (ETI), Hin1 and HSR203J of HR, PR1a of systemic acquired resistance (SAR) and the SAR related gene NPR1 were all up-regulated in transgenic tomato leaves overexpressing BvEP. …”
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    A novel elicitor protein phosphopentomutase from Bacillus velezensis LJ02 enhances tomato resistance to Botrytis cinerea
  16. 1256
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    Antidepressants for social anxiety disorder: A systematic review and meta‐analysis
  17. 1257
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    Findings of (18)F‐PI‐2620 tau PET imaging in patients with Alzheimer’s disease and healthy controls in relation to the plasma P‐tau181 levels in a Japanese sample
  18. 1258
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    A preliminary study on predictors of treatment response to repetitive transcranial magnetic stimulation in patients with treatment‐resistant depression in Japan
  19. 1259
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    Risk assessment of accidental falls in patients taking trazodone, quetiapine, or risperidone for insomnia: A single‐center, case–control study
  20. 1260
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    Relationship among psychotic features, benzodiazepine receptor agonists, and rehospitalization in patients with electroconvulsive therapy‐responsive major depressive disorder: A retrospective 2‐year observational study
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