“…Here, we present the crystal structure of human CCR7 fused to the protein Sialidase NanA by using data up to 2.1 Å resolution. The structure shows the ligand Cmp2105 bound to an intracellular allosteric binding pocket. …”
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“…Here we show ultra-near-field index modulated PlAsmonic NanO-apeRture lAbel-free iMAging (PANORAMA) which uniquely relies on unscattered light to detect sub-100 nm dielectric nanoparticles. …”
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“…Cu(2+)(,) Ni(2+), Fe(2+)(,) Ca(2+), and Co(2+) exhibited a complete activating effect on it, while Zn(2+), Mn(2+), NaN(3), PMSF, N-Methylmaleimide, and EDTA have inhibitory effect. …”
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“…This study is based on data from the cohort of older adults aged ≥65 years (n = 226) in the Irish National Adult Nutrition Survey (NANS) (2008–2010) which estimated food and nutrient intakes in a representative sample of adults 18–90 years using a 4 day weighed food record. …”
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“…In addition, the proposed mechanism indicates usefulness of this concept for both internal and terminal alkynes, eliminates the option to replace NIS by its Cl- or Br-analogues, and strongly promotes NaN(3) as an alternative to TMSN(3). Lastly, our results advise increasing the solvent polarity as another route to advance this metal-free strategy towards more efficient processes.…”
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“…Along with the legends about epidemic demons, China has developed over the centuries a medical approach based on the teachings of Huang Di Nei Jing ([Image: see text] Internal Classic), Nan Jing ([Image: see text] Classic of Difficulties), and Shang Han Lun ([Image: see text] Treatise of Harmful Cold). …”
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“…Genotypic analyses revealed clade 2 on the dendrogram of repetitive sequence-based fingerprinting, capsule serogroup cap genotype A, and hsf-1-nanH-pmHAS (virulence-associated genes). Our observations show that the two isolates have similar phenotypic and genotypic traits, regardless of differences in patient background, biting pets, wound inflammation, or the necessity of surgical intervention.…”
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“…Cubic delta-tantalum nitride (δ-TaN) nanoparticles were selectively prepared using a K(2)TaF(7) + (5 + k) NaN(3) + kNH(4)F reactive mixture (k being the number of moles of NH(4)F) via a combustion process under a nitrogen pressure of 2.0 MPa. …”
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“…The principle of combining five shu points is based on the theory of Nan-jing. The treatment and diagnosis concepts in Saam acupuncture were mainly influenced by Dongeuibogam and Chimgoogyeong-heombang. …”
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“…Different equations such as the Nan, Vogel-Fulcher-Tamman (VFT), or Maron-Pierce (MP) models were utilized to describe the temperature or nanoparticle concentration dependences of thermal conductivity and viscosity. …”
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“…In this study, we discovered isochaihulactone, a natural compound extracted from the Chinese traditional herb Nan-Chai-Hu, which can disrupt ER homeostasis in GBM cell lines. …”
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“…Immunostaining revealed nuclear accumulation of p53 within 6 h after various stresses [heat shock, osmotic shock, heavy metal (Cd), blockers of the cellular respiratory system (NaN(3)), amino acid analogues (azetidine and canavanine), an inhibitor of protein synthesis (puromycin), and oxygen free radicals (H(2)O(2))]. …”
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“…The synthesis of the former is achieved by the use of (t)BuNCO as a mild oxygen transfer reagent, whilst that of the latter is via the reduction of NaN(3). Both mono-uranium complexes are stabilised by the presence of bulky silyl substituents on the ligand framework that facilitate a 2e(–) oxidation of a single U(iii) centre. …”
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“…The data from ITS2 region indicated that 13 (62%) of the 21 samples labeled as “Nan-she-teng” and eight (31%) of the 26 samples labeled as “Lei-gong-teng” were authentic; the remaining were adulterants. …”
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“…The azide-capped it-PMMA was prepared by living anionic polymerization of MMA, which was initiated with t-BuMgBr in toluene at –78 °C, and was followed by termination using CCl(4) as the halogenating agent in the presence of a strong Lewis base and subsequent azidation with NaN(3). The alkyne-capped st-PMMA was obtained by living anionic polymerization of MMA, which was initiated via an in situ metal-halogen exchange reaction between 1,1-diphenylhexyl lithium and an α-bromoester bearing a pendent silyl-protected alkyne group. …”
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“…Additional findings obtained using intracellular dialysis of inorganic phosphate and alkaline phosphatase or NaN(3) treatment further support the involvement of a phosphorylation mechanism. …”
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“…In this paper, we propose a framework that preserves the secrecy of prosumers’ identities and provides protection against the traffic analysis attack in a competitive market for energy trade in a Neighborhood Area Network (NAN). In addition, the amount of bidders and of successful bids are hidden from malicious attackers by our framework. …”
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