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  1. 701
    “…In this study, to explore sperm motility-related molecular mechanisms, we compared the testis tissues transcriptomes from 2-year-old male COC and 4nAT. The RNA-seq data revealed that 2985 genes were differentially expressed between COC and 4nAT, including 2216 upregulated and 769 downregulated genes in 4nAT. …”
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    Different expression patterns of sperm motility-related genes in testis of diploid and tetraploid cyprinid fish(†)
  2. 702
    “…N-acetyltransferase 2 (NAT2) is a Phase II enzyme that specifically catalyzes the acetylation of INH, and NAT2 expression/activity play pivotal roles in INH metabolism, drug efficacy, and toxicity. …”
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    miR-15a-3p Protects Against Isoniazid-Induced Liver Injury via Suppressing N-Acetyltransferase 2 Expression
  3. 703
    “…In our center, all blood transfusions before 2015 were screened using non-NAT methods, while all blood transfusions were screened using NAT starting in 2015. …”
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    The impact of nucleic acid testing as a blood donor screening method in transfusion-associated hepatitis C among children with bleeding disorders in Indonesia: a single-center experience
  4. 704
    “…One such challenge is the lack of consensus on the optimal timing and duration of NAT. Improved criteria for patient selection are needed to further identify PDAC patients likely to respond to NAT. …”
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    Developments and challenges in neoadjuvant therapy for locally advanced pancreatic cancer
  5. 705
    “…BACKGROUND: Human N(α)-acetyltransferase complex B (hNatB) is integrated by hNaa20p (hNAT5/hNAT3) and hNaa25p (hMDM20) proteins. …”
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    Characterization of the human N(α)-terminal acetyltransferase B enzymatic complex
  6. 706
    “…In 8000 ELISA negative blood samples subjected to NAT, 4 donor samples were reactive for HBV. The NAT yield was 1 in 2000. …”
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    Automated nucleic acid amplification testing in blood banks: An additional layer of blood safety
  7. 707
    “…Here, we have investigated the role of NAT1 in the invasiveness of breast cancer cells both in vitro and in vivo. …”
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    Effects of human arylamine N-acetyltransferase I knockdown in triple-negative breast cancer cell lines
  8. 708
    “…Little polymorphism sharing was found among hominids, yet all species displayed high NAT diversity, but distributed in an opposite fashion in chimpanzees and bonobos (Pan genus) compared to modern humans, with higher diversity in Pan species at NAT1 and lower at NAT2, while the reverse is observed in humans. …”
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    Humans and Chimpanzees Display Opposite Patterns of Diversity in Arylamine N-Acetyltransferase Genes
  9. 709
    “…The most common haplotypes were NAT2*4 (28%) followed by NAT2*5B (27.4%), NAT2*6A (21.5%) and NAT2*12A (7.5%). …”
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    Validation of PHASE for deriving N-acetyltransferase 2 haplotypes in the Western Cape mixed ancestry population
  10. 710
    por Zhang, Yun, Huang, Zi-Xing, Song, Bin
    Publicado 2021
    “…Imaging plays a vital role in tumor response evaluation after NAT. However, conventional imaging modalities such as multidetector computed tomography have limited roles in the assessment of tumor resectability after NAT for PDAC because of the similar appearance of tissue fibrosis and tumor infiltration. …”
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    Role of imaging in evaluating the response after neoadjuvant treatment for pancreatic ductal adenocarcinoma
  11. 711
    “…The benefit of neoadjuvant treatment (NAT) for borderline resectable/locally advanced PDAC has been demonstrated; this evidence raises the question of whether even resectable PDAC should undergo NAT rather than upfront surgery. …”
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    Neoadjuvant Treatment in Resectable Pancreatic Cancer. Is It Time for Pushing on It?
  12. 712
    “…The modest clinical benefits of neoadjuvant chemotherapy (NAT) in pancreatic ductal adenocarcinoma (PDAC) are associated with a lack of robust data on treatment‐induced changes in the tumor. …”
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    Neoadjuvant chemotherapy is associated with an altered metabolic profile and increased cancer stemness in patients with pancreatic ductal adenocarcinoma
  13. 713
    “…RESULTS: In this study, a full-length complementary DNA (cDNA) encoding Schistosoma japonicum NAT13 (SjNAT13) was isolated from schistosome cDNAs. …”
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    Characterisation and preliminary functional analysis of N-acetyltransferase 13 from Schistosoma japonicum
  14. 714
    “…Our goal was to evaluate NAT incidence and severity during the pandemic across multiple US cities. …”
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    Association of Economic Recession and Social Distancing With Pediatric Non-accidental Trauma During COVID-19
  15. 715
    por Meyer, U A
    Publicado 1994
    “…Acetylation by arylamine N-acetyltransferases (NATs) is a major route in the metabolism of numerous drugs and carcinogens. …”
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    Polymorphism of human acetyltransferases.
  16. 716
    “…Here, we reported that in colorectal cancer cells the expression of NAT10 (N-acetyltransferase 10) could mediate MN formation through DNA replication and NAT10-positive MN could activate SASP by binding to cGAS. …”
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    N-Acetyltransferase 10 Promotes Micronuclei Formation to Activate the Senescence-Associated Secretory Phenotype Machinery in Colorectal Cancer Cells
  17. 717
    “…Herein, we report a case in which a woman was diagnosed with invasive ductal carcinoma in the left breast and received NAT before surgery. Automated breast ultrasound (AB US) was regularly performed before and during the NAT to evaluate the tumor response to NAT by measuring diameter changes and volume reductions of the tumor. …”
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    Assessment of Neoadjuvant Treatment Response Using Automated Breast Ultrasound in Breast Cancer
  18. 718
    “…OBJECTIVE: We evaluated the individual and combination effects of NAT1, NAT2 and tobacco smoking in a case-control study of 219 incident prostate cancer (PCa) cases and 555 disease-free men. …”
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    No Association Between Variant N-acetyltransferase Genes, Cigarette Smoking and Prostate Cancer Susceptibility Among Men of African Descent
  19. 719
    “…An uncommon but serious adverse event from NAT treatment is known as progressive multifocal leukoencephalopathy (PML). …”
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    Clinical adverse effects of natalizumab: Protocol for a meta-analysis of randomized double-blind placebo-controlled clinical trails
  20. 720
    por Hank, Thomas, Strobel, Oliver
    Publicado 2019
    “…While high-level evidence from prospective studies is still sparse, several large retrospective studies have recently reported their experience with NAT and conversion surgery for LAPC. This review aims to provide a current overview about different NAT regimens, conversion rates, survival outcomes and determinants of post-resection outcomes, as well as surgical strategies in the context of conversion surgery after NAT. …”
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    Conversion Surgery for Advanced Pancreatic Cancer
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