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  1. 161
    “…Synthesis of Zeb2 protein is controlled by a natural antisense transcript named Zeb2-NAT. We show that transfection of adult fibroblasts with specific LNA Gapmers induces a robust downregulation of Zeb2-NAT transcripts and Zeb2 protein and enhances the reprogramming of old fibroblasts into pluripotent cells. …”
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    Silencing of the lncRNA Zeb2-NAT facilitates reprogramming of aged fibroblasts and safeguards stem cell pluripotency
  2. 162
    “…Background: cis-NATs (cis-natural antisense transcripts ) are transcribed from opposite strands of adjacent genes and have been shown to regulate gene expression by generating small RNAs from the overlapping region. cis-NATs are important for plant development and resistance to pathogens and stress. …”
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    Cell-specific cis-natural antisense transcripts (cis-NATs) in the sperm and the pollen vegetative cells of Arabidopsis thaliana
  3. 163
    “…We show its functionality and the ability to completely N(α)-acetylate our model substrate α-synuclein both upon induction of the construct with L-arabinose and also by only relying on the constitutive expression of the NatB genes.…”
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    pTSara-NatB, an improved N-terminal acetylation system for recombinant protein expression in E. coli
  4. 164
    “…Background: Human N-acetyltransferase 10 (NAT10) plays pivotal roles in cellular biological processes, such as senescence, autophagy and cytokinesis. …”
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    miR-6716-5p promotes metastasis of colorectal cancer through downregulating NAT10 expression
  5. 165
    “…Additionally, the association between the NAT2 SNP and SDRs was validated in the PK cohort (rs1041983 TT vs. …”
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    Isoniazid Concentration and NAT2 Genotype Predict Risk of Systemic Drug Reactions during 3HP for LTBI
  6. 166
    “…Similarly, overexpression of miR-6744-5p in MDA-MB-231 increased anoikis and also decreased tumor cell invasion in vitro and in vivo. Furthermore, NAT1 enzyme was identified and validated as the direct target of miR-6744-5p. …”
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    MicroRNA-6744-5p promotes anoikis in breast cancer and directly targets NAT1 enzyme
  7. 167
    “…RESULTS: Considering the limitations of microscopy and the wide availability of the Brazilian NAT platform in the screening of blood units for HIV, HCV, and HBV, a molecular diagnostic tool was validated for detection of Plasmodium sp. in blood banks; a pilot study showed that using this novel NAT assay could reduce the risk of TTM. …”
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    Use of a NAT-based assay to improve the surveillance system and prevent transfusion-transmitted malaria in blood banks
  8. 168
    “…We found that NAT expression is tightly regulated by phosphate depletion and other naturally occurring environmental stresses. …”
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    Global identification of a marine diatom long noncoding natural antisense transcripts (NATs) and their response to phosphate fluctuations
  9. 169
    por Ruby, Perrine Marie
    Publicado 2020
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    The Neural Correlates of Dreaming Have Not Been Identified Yet. Commentary on “The Neural Correlates of Dreaming. Nat Neurosci. 2017”
  10. 170
    “…AIM: Since [(18)F, (nat)Ga]rhPSMA-7 is composed of four stereoisomers ([(18)F, (nat)Ga]rhPSMA-7.1, -7.2, -7.3 and -7.4), we initiated a preclinical selection process to identify the isomer with the most favorable pharmacokinetics for further clinical investigation. …”
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    Preclinical comparison of four [(18)F, (nat)Ga]rhPSMA-7 isomers: influence of the stereoconfiguration on pharmacokinetics
  11. 171
    “…NAT10 is also a potential biomarker in acute myeloid leukemia (AML); however, the mechanisms underlying NAT10’s contribution to disease states and the effect of targeting NAT10 as a therapeutic target remain unclear. …”
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    Targeting NAT10 Induces Apoptosis Associated With Enhancing Endoplasmic Reticulum Stress in Acute Myeloid Leukemia Cells
  12. 172
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    Natural history of Type 2 and 3 spinal muscular atrophy: 2‐year NatHis‐SMA study
  13. 173
    “…As eNAT can inactivate SARS-CoV-2, it may support COVID-19 diagnostics at the point of care. …”
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    Copan eNAT Transport System To Address Challenges in COVID-19 Diagnostics in Regions with Limited Testing Access
  14. 174
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    NAT10 promotes gastric cancer metastasis via N4-acetylated COL5A1
  15. 175
    Publicado 2021
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    Natural history of Type 2 and 3 spinal muscular atrophy: 2‐year NatHis‐SMA study
  16. 176
    “…BACKGROUND: Distinct N-acetyltransferase 2 (NAT2) slow acetylators genotypes have been associated with a higher risk to develop anti-tuberculosis drug-induced hepatotoxicity (DIH). …”
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    Homozygotes NAT2*5B slow acetylators are highly associated with hepatotoxicity induced by anti-tuberculosis drugs
  17. 177
    “…Notably, UNC-52-like kinase 1 (ULK1) is identified as the target of NAT10 in neutrophils. The decreased expression of NAT10 resultes in the decay of ULK1 transcripts and therefore the reduced expression of ULK1. …”
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    NAT10 regulates neutrophil pyroptosis in sepsis via acetylating ULK1 RNA and activating STING pathway
  18. 178
    “…In this study, we demonstrate that the only known ac(4)C writer, N-acetyltransferase 10 (NAT10), plays an essential role in male reproduction. …”
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    NAT10-mediated N(4)-acetylcytidine modification is required for meiosis entry and progression in male germ cells
  19. 179
    Publicado 2022
    “…Background: Over a decade, tissues dissected adjacent to primary tumors have been considered “normal” or healthy samples (NATs). However, NATs have recently been discovered to be distinct from both tumorous and normal tissues. …”
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    Classification of IHC Images of NATs With ResNet-FRP-LSTM for Predicting Survival Rates of Rectal Cancer Patients
  20. 180
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    Identification of the doubly-magic nucleus $^{100}$Sn in the reaction $^{112}$Sn + $^{nat}$Ni at 63 MeV/nucleon
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