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261“…Five of the newly synthesized compounds were selected by the National Cancer Institute (Bethesda, MD, USA) for a primary in vitro antitumor assay. 7-Chloro-3,5-diphenyl-thiazolo[4,5-d]pyrimidin-2-one (5a) proved to be the most active one among the screened derivatives and was further evaluated in the full panel of 60 cell lines at five different concentrations. …”
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262“…The model will be applied to grouped relative survival data for major cancer sites from the ‘Surveillance, epidemiology and end results’ program of the National Cancer Institute.…”
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263“…The antitumor activity of the synthesized compounds was tested in vitro by the National Cancer Institute in NCI60 cell lines. It was observed that some compounds showed slight anticancer activity. …”
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264“…Identification of novel markers for early identification of cancer is an established priority of the National Cancer Institute. The rapid expansion of genomic-based technologies developed over the last decade, and the development of sensitive and specific blood-based assays for the detection of molecular changes associated with cancer, begin to offer the means for achieving this goal. …”
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265por Demirayak, Seref, Yurttas, Leyla, Gundogdu-Karaburun, Nalan, Karaburun, Ahmet Cagri, Kayagil, Ismail“…For anticancer activity evaluation, all compounds were offered to National Cancer Institute (NCI), USA and selected ones were tested against sixty human tumor cell lines derived from nine neoplastic diseases. …”
Publicado 2017
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266por Montoya, Alba, Quiroga, Jairo, Abonia, Rodrigo, Derita, Marcos, Sortino, Maximiliano, Ornelas, Alfredo, Zacchino, Susana, Insuasty, Braulio“…Twelve of the new compounds were evaluated against 58 human cancer cell lines by the U.S. National Cancer Institute (NCI). Compounds 25, 30, 31, 36, and 37 showed significant cytostatic activity, with the most outstanding GI(50) values ranging from 0.05 to 0.95 µM. …”
Publicado 2016
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267“…The in vitro anticancer activity of compounds 11, 12, 14–21 and 24–26 was evaluated at the U.S. National Cancer Institute and in light of the results, some structure-activity relationships were discussed. …”
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268por Moreno-Astudillo, Liliana, Villaseñor-Navarro, Yolanda, Sánchez-Goytia, Vyanka, Porras-Reyes, Fany, Lara-Mercado, Alfredo, Sollozo-Dupont, Isabel“…Twelve patients were diagnosed between 2007 and 2017 at National Cancer Institute, Mexico. Solitary or multiple masses, round or oval, and hypoechoic and solid lesions with posterior acoustic shadowing were patterns commonly reported in these patients; other arrangements include diffuse involvement of the breast simulating an inflammatory carcinoma. …”
Publicado 2019
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269“…The Quantitative Imaging Network of the National Cancer Institute is in its 10th year of operation, and research teams within the network are developing and validating clinical decision support software tools to measure or predict the response of cancers to various therapies. …”
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270por Morigi, Rita, Catanzaro, Elena, Locatelli, Alessandra, Calcabrini, Cinzia, Pellicioni, Valentina, Leoni, Alberto, Fimognari, Carmela“…A series of new Knoevenagel adducts, bearing two indolinone systems, has been synthesized and evaluated on 60 human cancer cell lines according to protocols available at the National Cancer Institute (Bethesda, MD, USA). Some derivatives proved to be potent antiproliferative agents, showing GI(50) values in the submicromolar range. …”
Publicado 2021
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271Publicado 2021“…Daniel conducted the research described in this article while a doctoral student in Thomas Ried and Stephen Taylor's labs at the National Cancer Institute, Bethesda, MD, USA and the University of Manchester, Manchester, UK. …”
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272por Ku, Anson T., Shankavaram, Uma, Trostel, Shana Y., Zhang, Hong, Sater, Houssein A., Harmon, Stephanie A., Carrabba, Nicole V., Liu, Yang, Wood, Bradford J., Pinto, Peter A., Choyke, Peter L., Stoyanova, Radka, Davicioni, Elai, Pollack, Alan, Turkbey, Baris, Sowalsky, Adam G., Citrin, Deborah E.“…FUNDING: This research was supported by the Prostate Cancer Foundation, the Department of Defense Congressionally Directed Medical Research Program, National Cancer Institute, and the Intramural Research Program of the NIH, National Cancer Institute, Center for Cancer Research.…”
Publicado 2023
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273por Woloshin, Steven, Landsman, Victoria, Miller, Daniel G., Byrne, Jeffrey, Graubard, Barry I., Feuer, Eric J.“…OBJECTIVE: To update the National Cancer Institute’s Know Your Chances website to present mortality estimates for a broad set of causes of death and all causes combined by smoking status in addition to age, sex, and race. …”
Publicado 2023
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274por Kehm, Rebecca D., Llanos, Adana A. M., McDonald, Jasmine A., Tehranifar, Parisa, Terry, Mary Beth“…ABSTRACT: The National Cancer Institute (NCI) has established an online repository of evidence-based cancer control programs (EBCCP) and increasingly calls for the usage of these EBCCPs to reduce the cancer burden. …”
Publicado 2022
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275por Toraason, Mark, Albertini, Richard, Bayard, Steven, Bigbee, William, Blair, Aaron, Boffetta, Paolo, Bonassi, Stefano, Chanock, Steven, Christiani, David, Eastmond, David, Hanash, Samuel, Henry, Carol, Kadlubar, Fred, Mirer, Frank, Nebert, Daniel, Rapport, Stephen, Rest, Kathleen, Rothman, Nathaniel, Ruder, Avima, Savage, Russell, Schulte, Paul, Siemiatycki, Jack, Shields, Peter, Smith, Martyn, Tolbert, Paige, Vermeulen, Roel, Vineis, Paolo, Wacholder, Sholom, Ward, Elizabeth, Waters, Michael, Weston, Ainsley“…To address these questions, the National Institute for Occupational Safety and Health, the National Cancer Institute, the National Institute of Environmental Health Sciences, and the American Chemistry Council sponsored a workshop 8-9 May 2002 in Washington, DC. …”
Publicado 2004
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276“…Relative survival rates in the National Cancer Institute (NCI) 'SEER' review of cancer in the USA are fitted by a model which can be used to estimate median survival time in any calendar year. …”
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277“…The antitumour activities of four triorganophosphinegold(I) thiolates, R(2)PAu(S′R) [R = Ph, Cy, Et; SR′H = 6-mercaptopurine and R Et; SR′H = 6-thioguanine] against the National Cancer Institute (NCI) panel of 60 cell lines are reported The [Cy(3)PAu(6-MP)] complex proved to be the more cytotoxic of the four complexes tested. …”
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278“…Here, we present one of the National Cancer Institute’s recently established Integrative Cancer Biology Programs, i.e. the Center for the Development of a Virtual Tumor, CViT, which is charged with building a cancer modeling community, developing the aforementioned enabling technologies and fostering multi-scale cancer modeling and simulation.…”
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279“…We here used a chemical biology/chemical informatic approach to identify apoptotic mechanisms that are insensitive to activation of the PI3K/AKT pathway. The National Cancer Institute (NCI) Mechanistic Set drug library was screened for agents that induce apoptosis in colon carcinoma cells expressing a constitutively active form of AKT1. …”
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280por Shuh, Maureen“…Derse, Ph.D., Head of the Retrovirus Gene Expression Section in the HIV Drug Resistance Program at the National Cancer Institute-Frederick (NCI-Frederick), passed away on October 9, 2009, a scant six weeks after being diagnosed with liver cancer. …”
Publicado 2009
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