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421por Ruch, Randall J.“…To address this, Connexin43 (Cx43), the major human lung epithelial gap junction protein, was expressed ectopically in poorly expressing National Cancer Institute-125 (NCI-H125) metastatic human lung adenocarcinoma cells, and phenotypic characteristics of malignant cells and abundance of CSCs were evaluated. …”
Publicado 2019
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422por Kunos, Charles A., Capala, Jacek, Finnigan, Shanda, Smith, Gary L., Ivy, Susan Percy“…About two in every five women with advanced stage ovarian cancer outlive their disease after the first treatment phase, with the rest rendered incurable due to the chemorefractory nature of their disease. The National Cancer Institute (NCI) Cancer Therapy Evaluation Program conducted 67 phase I or phase Ib trials among women with relapsed or refractory ovarian cancer between 1989 and 2017 in an effort to uncover tolerable and effective drug combinations intended to increase survival rates. …”
Publicado 2019
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423“…Data have been supplemented with the information obtained from publicly available data repositories including PubMed, World Health Organization, National Cancer Institute, Centers for Disease Control and Prevention, European Cancer Information System, and many others to bring the historical context of this study. (3) Among the total of 2563 clinical trials included in the analysis, most have been registered in the USA (1487), which is 58% of the total. …”
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424por Zhu, Siyu, Zhang, Chaozai, Huang, Lina S., Zhang, Xing-Quan, Xu, Yan, Fang, Xiong, Zhou, Jiao, Wu, Meixian, Schooley, Robert T., Huang, Ziwei, An, Jing“…In this study, an in silico screening of the National Cancer Institute (NCI) diversity set based on ZIKV NS3 helicase was performed using a molecular docking approach. …”
Publicado 2019
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425“…By screening the full National Cancer Institute (NCI) panel, including 60 human cancer cell lines, four molecules displayed good and sometimes better growth inhibition GI(50) than the ROCK inhibitor Y-27632, the Topo II inhibitor podophyllotoxin and the tubulin inhibitor combretastatin A-4. …”
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426por Ferreira, Naidhia Alves Soares, Schoueri, Jean Henri Maselli, Sorpreso, Isabel Cristina Esposito, Adami, Fernando, dos Santos Figueiredo, Francisco Winter“…Information from Brazilian women diagnosed with breast cancer between 1998 and 2012 was collected through the Hospital Registry of Cancer (HRC), developed by the National Cancer Institute (INCA). We performed a secondary data analysis, and found that the majority of women (81.3%) waited for ≤60 days to start treatment after being diagnosed. …”
Publicado 2020
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427por Njuguna, Diana Wangeshi, Mahrouseh, Nour, Onisoyonivosekume, Dede, Varga, Orsolya“…Legal documents were searched uniformly from government websites, national cancer institute sites, and international and national legal databases, then the data were analyzed using the Nvivo12 software package. …”
Publicado 2020
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428“…The United States National Cancer Institute (NCI) Cancer Therapy Evaluation Program studies experimental therapeutic agents like radiopharmaceuticals in both early and late phase trials, which provide opportunities to comprehend more clearly the possible sources of financial toxicity incurred by cancer survivors. …”
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429por Ghosh, Rajat, Vitor, Jorge B., Mendes, Eduarda, Paulo, Alexandra, Acharya, Pratap Chandra“…The newly synthesized spirooxindole derivatives were evaluated for their antiproliferative efficacy against National Cancer Institute (NCI)-60 cancer cell lines and DNA G-quadruplex (G4) interaction capacity. …”
Publicado 2020
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430por Kunos, Charles A., Howells, Rodney, Chauhan, Aman, Myint, Zin W., Bernard, Mark E., El Khouli, Riham, Capala, Jacek“…We anticipate in the near-term that radiopharmaceutical trials will become a larger proportion of the National Cancer Institute Cancer Therapy Evaluation Program (CTEP) portfolio.…”
Publicado 2021
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431“…This article reports on a National Cancer Institute–funded training program to prepare advanced practice nurses to incorporate palliative care within their practice. …”
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432por Vallejo, Alexandra, González, Iván D, Guerrero Lizcano, Eduardo, Forero, Oscar, Enciso, Leonardo“…With our case series, we aim at sharing the experience of four patients diagnosed and treated at the National Cancer Institute between 2010 and 2020, establishing a correlation of the clinical, imaging, and histopathological presentation, the response to treatment based on radiotherapy and chemotherapy, and the clinical outcomes reported in the medical records.…”
Publicado 2021
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433por Stevens, Kathleen R., de la Rosa, Elisabeth, Ferrer, Robert L., Finley, Erin P., Flores, Bertha E., Forgione, Dana A., Noel, Polly Hitchcock, Reistetter, Timothy A., Valerio-Shewmaker, Melissa, Wooten, Kevin C.“…The Workshop combined internal and external expertise, targeted nationally established IR competencies, incorporated new National Institutes of Health/National Cancer Institute OpenAccess online resources, employed well-known adult education principles, and measured impact. …”
Publicado 2021
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434“…This analogue displayed the desired fluorescence properties along with significant biological activity in the National Cancer Institute’s 60-cell line bioassay, and the pattern of this biological activity mirrored that of the natural product schweinfurthin F. …”
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435por Mohammed, Altaf, Dashwood, Roderick H., Dickinson, Sally, Disis, Mary L., Jaffee, Elizabeth M., Johnson, Bryon D., Khleif, Samir N., Pollak, Michael N., Schlom, Jeffrey, Shoemaker, Robert H., Stanton, Sasha E., Wondrak, Georg T., You, Ming, Zhu, Hao, Miller, Mark Steven“…The National Cancer Institute (NCI) Division of Cancer Prevention (DCP) convened the “Translational Advances in Cancer Prevention Agent Development (TACPAD) Workshop on Immunomodulatory Agents” as a virtual 2-day workshop on September 13 to 14, 2021. …”
Publicado 2021
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436“…Based on the National Cancer Institute’s multi-institutional TCIA data set containing FDG-PET/CT/dose, a 3D deep learning model was proposed to predict LR without time-consuming segmentation or feature extraction. …”
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437“…The GFA-SVR model and associated pharmacophore models were used to screen the National Cancer Institute (NCI) structural database for novel CLK4 antagonists. …”
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438“…Method: The Surveillance, Epidemiology, and End Results program of the National Cancer Institute was searched for all cases of porocarcinomas diagnosed between 2000 and 2018. …”
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439por Menakuru, Sasmith R., Azeem, Qiraat, Priscu, Adelina, Khan, Ibrahim, Beirat, Amir“…The authors report the first case of stage 4 cytokine release syndrome (CRS) (graded by the National Cancer Institute Common Terminology Criteria for Adverse Effects scale) involving a patient with advanced metastatic melanoma who was treated with the combination of two monoclonal antibodies, nivolumab (anti-programmed cell death receptor 1 inhibitor [PD-1]) and ipilimumab (a cytotoxic T lymphocyte-associated antigen 4 inhibitor [CTLA-4]) after her first dose of both. …”
Publicado 2022
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440“…Currently, he is Senior Investigator at the Center for Structural Biology, National Cancer Institute in Frederick, Maryland, USA. He received his Ph.D. from the University of California, Los Angeles in 1974, completed postdoctoral training at Stanford University and has also worked at the National Bureau of Standards, the ABL‐Basic Research Program at the NCI‐FCRDC and the University of Cambridge, UK. …”
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