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4901por Euden, Joanne, Thomas-Jones, Emma, Aston, Stephen, Brookes-Howell, Lucy, Carman, Julie, Carrol, Enitan, Gilbert, Stephanie, Howard, Philip, Hood, Kerenza, Inada-Kim, Matthew, Llewelyn, Martin, McGill, Fiona, Milosevic, Sarah, Niessen, Louis Wihelmus, Nsutebu, Emmanuel, Pallmann, Philip, Schmidt, Paul, Taylor-Robinson, David, Welters, Ingeborg, Todd, Stacy, French, Neil“…In England, the National Early Warning Score 2 (NEWS2) has been mandated across all National Health Service (NHS) trusts and ambulance organisations. …”
Publicado 2022
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4902“…Even under conservative assumptions (efficacy equivalent to that of MeNZB and protection lasting for 18 months after two-dose primary vaccination and 36 months after single-dose booster vaccination), 4CMenB administered under VaR would likely be cost-saving at its current National Health Service price, averting an estimated mean 110 200 cases (95% credible interval 36 500–223 600), gaining a mean 100·3 QALYs (31·0–215·8), and saving a mean £7·9 million (0·0–20·5) over 10 years. …”
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4903por Ibrahim, Ali, Ryan, Sharon, Viljoen, David, Tutisani, Ellen, Gardner, Lucy, Collins, Lorna, Ayton, Agnes“…To address this, the Oxford service has adapted the enhanced cognitive behavioural treatment (CBTE) model, first developed for inpatients in Italy to a UK national health service (NHS) setting. In this study, we compared the outcomes from treatment as usual (TAU), integrated CBTE (I-CBTE), and alternative treatment models in routine UK clinical practice. …”
Publicado 2022
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4904por Myall, Ashleigh, Price, James R, Peach, Robert L, Abbas, Mohamed, Mookerjee, Sid, Zhu, Nina, Ahmad, Isa, Ming, Damien, Ramzan, Farzan, Teixeira, Daniel, Graf, Christophe, Weiße, Andrea Y, Harbarth, Stephan, Holmes, Alison, Barahona, Mauricio“…We trained and tested the framework on HOCIs using the data from 51 157 hospital inpatients admitted to a UK National Health Service hospital group (Imperial College Healthcare NHS Trust) between April 1, 2020, and April 1, 2021, intersecting the first two COVID-19 surges. …”
Publicado 2022
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4905por Froes, Filipe, Carmo, Mafalda, Lopes, Hugo, Bizouard, Geoffray, Gomes, Catarina, Martins, Margarida, Bricout, Hélène, de Courville, Caroline, de Sousa, Jaime Correia, Rabaçal, Carlos, Raposo, João F., Cordeiro, Carlos Robalo“…METHODS: The study comprised ten epidemic seasons (2008/09–2017/18) and used two approaches: (i) a direct method of estimating the seasonal influenza hospitalization incidence, based on the number of National Health Service hospitalizations with influenza-specific International Classification of Diseases (ICD) codes (ICD-9: 487–488; ICD-10: J09-J11), as primary or secondary diagnosis; (ii) an indirect method of estimating excess hospitalizations and deaths using broader groups of ICD codes in time-series models, computed for six age groups and four groups of diagnoses: pneumonia or influenza (ICD-9: 480–488, 517.1; ICD-10: J09–J18), respiratory (ICD-9: 460–519; ICD-10: J00–J99), respiratory or cardiovascular (R&C, ICD-9: 390–459, 460–519; ICD-10: I00–I99, J00–J99), and all-cause. …”
Publicado 2022
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4906“…METHODS: This was a definitive superiority randomized controlled trial with 2182 National Health Service staff in England recruited on the web and allocated in a 1:1 ratio to fully automated Headspace (n=1095, 50.18%) or active control (Moodzone; n=1087, 49.82%) for 4.5 months. …”
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4907por Sedda, Luigi, Ashish, Abdul, Unsworth, Alison, Martindale, Jane, Sundar, Ramachandaran, Farrier, Martin“…SETTING: The acute inpatient unit in Wrightington, Wigan and Leigh Teaching Hospitals National Health Service (NHS) Foundation Trust (WWL), a medium-sized NHS Trust in north-west of England. …”
Publicado 2022
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4908por Wijnen, Ben, Witlox, Willem, Wolff, Robert, Fayter, Debra, Ramaekers, Bram, Otten, Thomas, Ryder, Steve, Posadzki, Pawel, Worthy, Gill, Stirk, Lisa, Armstrong, Nigel, Kleijnen, Jos, Joore, Manuela“…Fenfluramine was recommended as an add-on to other antiepileptic medicines for treating seizures associated with DS in people aged 2 years and older in the National Health Service (NHS).…”
Publicado 2022
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4909por Pegington, Mary, Harvie, Michelle, Harkness, Elaine F., Brentnall, Adam, Malcomson, Lee, Southworth, Jake, Fox, Jill, Howell, Anthony, Cuzick, Jack, Evans, D. Gareth“…METHODS: The Predicting Risk of Cancer At Screening (PROCAS) study recruited 57,902 women aged 46–73 years (median age 57.2, IQR 51.8–63.7 years) from the Greater Manchester National Health Service breast screening programme in North West England between 2009 and 2015. …”
Publicado 2023
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4910por Pumarola, T., Díez-Domingo, J., Martinón-Torres, F., Redondo Margüello, E., de Lejarazu Leonardo, R. Ortiz, Carmo, M., Bizouard, G., Drago, G., López-Belmonte, J. L., Bricout, H., de Courville, C., Gil-de-Miguel, A.“…METHODS: The study comprised ten epidemic seasons (2008/2009–2017/2018) and used two approaches: (i) a direct method of estimating the seasonal influenza hospitalization, based on the number of National Health Service hospitalizations with influenza-specific International Classification of Diseases (ICD) codes (ICD-9: 487–488; ICD-10: J09-J11), as primary or secondary diagnosis; (ii) an indirect method of estimating excess hospitalizations and deaths using broader groups of ICD codes in time-series models, computed for six age groups and four groups of diagnoses: pneumonia or influenza (ICD-9: 480–488, 517.1; ICD-10: J09–J18), respiratory (ICD-9: 460–519; ICD-10: J00–J99), respiratory or cardiovascular (C&R, ICD-9: 390–459, 460–519; ICD-10: I00–I99, J00–J99), and all-cause. …”
Publicado 2023
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4911por Dewez, Juan Emmanuel, Nijman, Ruud G., Fitchett, Elizabeth J. A., Lynch, Rebecca, de Groot, Ronald, van der Flier, Michiel, Philipsen, Ria, Vreugdenhil, Harriet, Ettelt, Stefanie, Yeung, Shunmay“…In England, the funding constraints of the National Health Service and the prioritization of alternative and less expensive antimicrobial stewardship interventions prevented the development of a reimbursement scheme. …”
Publicado 2023
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4912por Marsden, John, Kelleher, Mike, Gilvarry, Eilish, Mitcheson, Luke, Bisla, Jatinder, Cape, Angela, Cowden, Fiona, Day, Edward, Dewhurst, Jonathan, Evans, Rachel, Hardy, Will, Hearn, Andrea, Kelly, Joanna, Lowry, Natalie, McCusker, Martin, Murphy, Caroline, Murray, Robert, Myton, Tracey, Quarshie, Sophie, Vanderwaal, Rob, Wareham, April, Hughes, Dyfrig, Hoare, Zoë“…METHODS: This pragmatic, parallel-group, open-label, multi-centre, effectiveness superiority randomised, controlled, phase 3 trial was conducted at five National Health Service community-based treatment clinics in England and Scotland. …”
Publicado 2023
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4913por Tosas Auguet, Olga, Betley, Jason R., Stabler, Richard A., Patel, Amita, Ioannou, Avgousta, Marbach, Helene, Hearn, Pasco, Aryee, Anna, Goldenberg, Simon D., Otter, Jonathan A., Desai, Nergish, Karadag, Tacim, Grundy, Chris, Gaunt, Michael W., Cooper, Ben S., Edgeworth, Jonathan D., Kypraios, Theodore“…METHODS AND FINDINGS: This study involved spatial analysis of cross-sectional data linked with all MRSA isolates identified by three National Health Service (NHS) microbiology laboratories between 1 November 2011 and 29 February 2012. …”
Publicado 2016
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4914por Goodyer, Ian M, Reynolds, Shirley, Barrett, Barbara, Byford, Sarah, Dubicka, Bernadka, Hill, Jonathan, Holland, Fiona, Kelvin, Raphael, Midgley, Nick, Roberts, Chris, Senior, Rob, Target, Mary, Widmer, Barry, Wilkinson, Paul, Fonagy, Peter“…METHODS: We did this multicentre, pragmatic, observer-blind, randomised controlled superiority trial (IMPACT) at 15 National Health Service child and adolescent mental health service (CAMHS) clinics in three regions in England. …”
Publicado 2017
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4915por Hickman, Matthew, Dillon, John F, Elliott, Lawrie, De Angelis, Daniela, Vickerman, Peter, Foster, Graham, Donnan, Peter, Eriksen, Ann, Flowers, Paul, Goldberg, David, Hollingworth, William, Ijaz, Samreen, Liddell, David, Mandal, Sema, Martin, Natasha, Beer, Lewis J Z, Drysdale, Kate, Fraser, Hannah, Glass, Rachel, Graham, Lesley, Gunson, Rory N, Hamilton, Emma, Harris, Helen, Harris, Magdalena, Harris, Ross, Heinsbroek, Ellen, Hope, Vivian, Horwood, Jeremy, Inglis, Sarah Karen, Innes, Hamish, Lane, Athene, Meadows, Jade, McAuley, Andrew, Metcalfe, Chris, Migchelsen, Stephanie, Murray, Alex, Myring, Gareth, Palmateer, Norah E, Presanis, Anne, Radley, Andrew, Ramsay, Mary, Samartsidis, Pantelis, Simmons, Ruth, Sinka, Katy, Vojt, Gabriele, Ward, Zoe, Whiteley, David, Yeung, Alan, Hutchinson, Sharon J“…Our findings will have direct National Health Service and patient relevance; informing prioritisation given to early HCV treatment for PWID. …”
Publicado 2019
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4916por Gumley, Andrew, Bradstreet, Simon, Ainsworth, John, Allan, Stephanie, Alvarez-Jimenez, Mario, Beattie, Louise, Bell, Imogen, Birchwood, Max, Briggs, Andrew, Bucci, Sandra, Castagnini, Emily, Clark, Andrea, Cotton, Sue M, Engel, Lidia, French, Paul, Lederman, Reeva, Lewis, Shon, Machin, Matthew, MacLennan, Graeme, Matrunola, Claire, McLeod, Hamish, McMeekin, Nicola, Mihalopoulos, Cathrine, Morton, Emma, Norrie, John, Reilly, Frank, Schwannauer, Matthias, Singh, Swaran P, Smith, Lesley, Sundram, Suresh, Thomson, David, Thompson, Andrew, Whitehill, Helen, Wilson-Kay, Alison, Williams, Christopher, Yung, Alison, Farhall, John, Gleeson, John“…Our primary outcomes are establishing parameters of feasibility, acceptability, usability, safety, and outcome signals of a digital health intervention as an adjunct to usual care that is deliverable in the UK National Health Service and Australian community mental health service (CMHS) settings. …”
Publicado 2020
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4917por Marsden, John, White, Martin, Annand, Fizz, Burkinshaw, Peter, Carville, Serena, Eastwood, Brian, Kelleher, Michael, Knight, Jonathan, O'Connor, Rosanna, Tran, Anh, Willey, Peter, Greaves, Felix, Taylor, Stephen“…METHODS: This was a mixed-methods public health review, comprising a rapid evidence assessment of articles (Jan 1, 2008, to Oct 3, 2018; with searches of MEDLINE, Embase, and PsycINFO, and the Cochrane and King's Fund libraries), an open call-for-evidence on patient experience and service evaluations, and a retrospective, patient-linked analysis of the National Health Service (NHS) Business Services Authority prescription database (April 1, 2015, to March 30, 2018) for all adults aged 18 years and over. …”
Publicado 2019
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4918por Jackson, Graham H, Davies, Faith E, Pawlyn, Charlotte, Cairns, David A, Striha, Alina, Collett, Corinne, Waterhouse, Anna, Jones, John R, Kishore, Bhuvan, Garg, Mamta, Williams, Cathy D, Karunanithi, Kamaraj, Lindsay, Jindriska, Wilson, Jamie N, Jenner, Matthew W, Cook, Gordon, Kaiser, Martin F, Drayson, Mark T, Owen, Roger G, Russell, Nigel H, Gregory, Walter M, Morgan, Gareth J“…METHODS: The Myeloma XI trial was an open-label, randomised, phase 3, adaptive design trial done at 110 National Health Service hospitals in the UK. There were three potential randomisations in the study: induction treatment, intensification treatment, and maintenance treatment. …”
Publicado 2019
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4919por Kontis, Dimitrios, Andreopoulou, Angeliki, Vassilouli, Spyridoula, Giannakopoulou, Dimitra, Siettou, Eleni, Giannoulis, Alexandros, Louki, Fedra, Tsaltas, Eleftheria, Theochari, Eirini“…The CRP is implemented at a specialized Unit of the Greek National Health Service which is located in the centre of Athens for patients with SCZ living in the community. …”
Publicado 2020
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4920por Hellyer, Thomas P, McAuley, Daniel F, Walsh, Timothy S, Anderson, Niall, Conway Morris, Andrew, Singh, Suveer, Dark, Paul, Roy, Alistair I, Perkins, Gavin D, McMullan, Ronan, Emerson, Lydia M, Blackwood, Bronagh, Wright, Stephen E, Kefala, Kallirroi, O'Kane, Cecilia M, Baudouin, Simon V, Paterson, Ross L, Rostron, Anthony J, Agus, Ashley, Bannard-Smith, Jonathan, Robin, Nicole M, Welters, Ingeborg D, Bassford, Christopher, Yates, Bryan, Spencer, Craig, Laha, Shondipon K, Hulme, Jonathan, Bonner, Stephen, Linnett, Vanessa, Sonksen, Julian, Van Den Broeck, Tina, Boschman, Gert, Keenan, DW James, Scott, Jonathan, Allen, A Joy, Phair, Glenn, Parker, Jennie, Bowett, Susan A, Simpson, A John“…METHODS: VAPrapid2 was a multicentre, randomised controlled trial in patients admitted to 24 ICUs from 17 National Health Service hospital trusts across England, Scotland, and Northern Ireland. …”
Publicado 2020
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