“…The Middle-to-Upper Paleolithic transition in Europe covers the last millennia of Neanderthal life together with the appearance and expansion of Modern Human populations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Throughout the past decade, studying ancient genomes has provided unique insights into human prehistory, and differences between modern humans and other branches like Neanderthals can enrich our understanding of the molecular basis of unique modern human traits. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Herein, we will focus on some recently studied forms of human adaptation to infectious agents, including hybridization with now-extinct hominins, such as Neanderthals and Denisovans, and admixture between modern human populations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…There was no sign of strong selection of the highly conservative GRID2 gene in ancient hominids (Neanderthals and Denisovans) or modern humans; however, according to in silico tests using the Mfold tool, the GRID2 gene possibly gained human-specific mutations that increased the stability of GRID2 mRNA.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We confirm previous observations that East Asian individuals have more Neanderthal ancestry than European individuals, but surprisingly, when we compare the number of single nucleotide polymorphisms with archaic alleles found across a population, Europeans have more Neanderthal ancestry than East Asians. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The risk haplotype, which was inherited from Neanderthals, decreases the expression of several cytokine receptors, including CCR5. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The lack of these morphological traits in Neanderthals, who lived in cold environments, seems a paradox, but it is probably the consequence of a warm-adapted faces together with precocious maturation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We compared these with the alleles in chimpanzees and gorillas. Neanderthal and Denisovan hominins predominantly possess gene variants conferring increased resistance to these toxic compounds. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The results show that distance hunting was likely within the repertoire of hunting strategies of Neanderthals, and the resulting behavioural flexibility closely mirrors that of our own species.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We investigated the evolutionary pressures acting on almost all human protein-coding genes (N = 11,667; 1:1 orthologs in primates) based on their divergence from those of early hominins, such as Neanderthals, and non-human primates. We confirm that genes encoding brain-related proteins are among the most strongly conserved protein-coding genes in the human genome. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We present evidence that this deletion was nearly fixed in the ancestral population of anatomically modern humans and Neanderthals but underwent a recent adaptive reduction in frequency in East Asia. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our sample includes chimpanzees, early hominins, early Homo Neanderthals, as well as prehistoric and recent humans. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Comparative inter-regional analysis of core technology indicates morphological similarities with the Levantine Tabun C assemblage, associated with human fossils controversially identified as either Neanderthals or Homo sapiens.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A central challenge is to estimate the timing of past admixture and divergence events, for example the time at which Neanderthals exchanged genetic material with humans and the time at which modern humans left Africa. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The CI event is of particular interest not only to investigate the role of volcanism on climate forcing and palaeoenvironments, but also because its timing coincides with the arrival into Europe of anatomically modern humans, the demise of Neanderthals, and an associated major shift in lithic technology. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Competitive interactions between African modern humans and Indian archaics who shared an adaptation to tropical environments differed from that between modern humans and archaics like Neanderthals and Denisovans, who were adapted to temperate environments. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The Lys/GGPM motif is present in the DPβ sequence of the Neanderthal genome, and this ancient sequence is related to the human allele DPB1*0401. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We also applied it to 1,000 Genomes and Complete Genomics data combined with high-coverage Denisovan and Neanderthal genomes to test for sweeps in modern humans since the separation from the Neanderthal–Denisovan ancestor. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In recent research (Boeckx and Benítez-Burraco, 2014a,b) have advanced the hypothesis that our species-specific language-ready brain should be understood as the outcome of developmental changes that occurred in our species after the split from Neanderthals-Denisovans, which resulted in a more globular braincase configuration in comparison to our closest relatives, who had elongated endocasts. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Comparisons of whole-genome sequences from ancient and contemporary samples have pointed to several instances of archaic admixture through interbreeding between the ancestors of modern non-Africans and now extinct hominids such as Neanderthals and Denisovans. One implication of these findings is that some adaptive features in contemporary humans may have entered the population via gene flow with archaic forms in Eurasia. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso