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Mostrando 321 - 340 Resultados de 434 Para Buscar '"Neanderthals"', tiempo de consulta: 0.36s Limitar resultados
  1. 321
    “…This series also represents an “off-site” reference record for chronologically well-constrained Palaeolithic sites documenting Neanderthal and Homo sapiens occupations within the same region. …”
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    High-resolution ecosystem changes pacing the millennial climate variability at the Middle to Upper Palaeolithic transition in NE-Italy
  2. 322
    “…In this study, we show that while analyses of population history using such panels work well for studies of relationships among non-African populations and one African outgroup, when co-modeling more than one sub-Saharan African and/or archaic human groups (Neanderthals and Denisovans), fitting of f-statistics to such SNP sets is expected to frequently lead to false rejection of true demographic histories, and failure to reject incorrect models. …”
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    Modeling of African population history using f-statistics is biased when applying all previously proposed SNP ascertainment schemes
  3. 323
    “…However, dispersal across the Levant would better explain the introgression with Neanderthals, and more than one exit would fit better with the different ancient genomic components discovered in indigenous Australians and in ancient Europeans. …”
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    Carriers of Mitochondrial DNA Macrohaplogroup N Lineages Reached Australia around 50,000 Years Ago following a Northern Asian Route
  4. 324
    por Facco, Enrico, Zanette, Gastone
    Publicado 2017
    “…Archeological findings suggest that humans have been surprisingly skillful and knowledgeable since prehistory. Neanderthals used medicinal plants; and relics of dental tools bear witness to a kind of Neolithic proto-dentistry. …”
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    The Odyssey of Dental Anxiety: From Prehistory to the Present. A Narrative Review
  5. 325
    “…The enrichment was not observed for Neanderthal or Denisovan DMRs. The enrichment seen in human DMRs is comparable to that for genomic regions tagged by Neanderthal Selective Sweep markers, and stronger than that for Human Accelerated Regions. …”
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    Recently evolved human-specific methylated regions are enriched in schizophrenia signals
  6. 326
    por Pfeifer, Bastian, Kapan, Durrell D.
    Publicado 2019
    “…These methods have been applied to a variety of genomic systems ranging from butterflies to Neanderthals to detect introgression, however, when employed at a fine genomic scale these methods do not perform well to quantify introgression in small sample windows. …”
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    Estimates of introgression as a function of pairwise distances
  7. 327
    “…The genomes of present-day humans outside Africa originated almost entirely from a single out-migration ~ 50,000–70,000 years ago, followed by mixture with Neanderthals contributing ~ 2% to all non-Africans. However, the details of this initial migration remain poorly understood because no ancient DNA analyses are available from this key time period, and interpretation of present-day autosomal data is complicated due to subsequent population movements/reshaping. …”
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    A Southeast Asian origin for present-day non-African human Y chromosomes
  8. 328
    “…Archaeological and palaeontological records from the Levantine woodland zone document major biological and cultural shifts, such as alternating occupations by Homo sapiens and Neanderthals. However, Late Quaternary cultural, biological and environmental records from the vast arid zone that constitutes most of Southwest Asia remain scarce, limiting regional-scale insights into changes in hominin demography and behaviour(1,2,5). …”
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    Multiple hominin dispersals into Southwest Asia over the past 400,000 years
  9. 329
    “…Intriguingly, this low-producing variant that is endemic to present-day Asia was found in early humans who had inhabited mainland Asia since ∼40,000 years ago but not in other ancient humans, such as Neanderthals and Denisovans. The present study suggests that an individual's IL-6 genotype underlies COVID-19 outcome and may be used to guide IL-6 blockade therapy in Asian patients.…”
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    A Low-Producing Haplotype of Interleukin-6 Disrupting CTCF Binding Is Protective against Severe COVID-19
  10. 330
    “…Archaic admixture has had a substantial impact on human evolution with multiple events across different clades, including from extinct hominins such as Neanderthals and Denisovans into modern humans. In great apes, archaic admixture has been identified in chimpanzees and bonobos but the possibility of such events has not been explored in other species. …”
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    Ghost admixture in eastern gorillas
  11. 331
    por Glinsky, Gennadi V.
    Publicado 2015
    “…Sequences of only 4.3% of hESC-specific NANOG-binding sites are present in Neanderthals’ genome, suggesting that a majority of these regulatory elements emerged in Modern Humans. …”
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    Transposable Elements and DNA Methylation Create in Embryonic Stem Cells Human-Specific Regulatory Sequences Associated with Distal Enhancers and Noncoding RNAs
  12. 332
    “…Remarkably, E154 is the ancestral residue in mammalian IFNλ4s and is extremely well conserved, yet K154 has been fixed throughout evolution of the hominid genus Homo, including Neanderthals. Compared to chimpanzee IFNλ4, the human orthologue had reduced activity due to amino acid K154. …”
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    A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages
  13. 333
    “…Despite recent evidence for Y chromosome introgression from humans into Neanderthals, we find that the Neanderthal PAR1 retained similarity to the Denisovan sequence. …”
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    Evolutionary dynamics of pseudoautosomal region 1 in humans and great apes
  14. 334
    “…But the bias introduced by common ascertainments such as the 1240K panel is mostly limited to situations when more than one sub-Saharan African and/or archaic human groups (Neanderthals and Denisovans) or non-human outgroups are co-modelled, for example, f(4)-statistics involving one non-African group, two African groups, and one archaic group. …”
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    Modeling of African population history using f-statistics can be highly biased and is not addressed by previously suggested SNP ascertainment schemes
  15. 335
    “…Climatic conditions and the presence of Neanderthals and other hominins might have played significant roles in these human movements. …”
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    Carriers of mitochondrial DNA macrohaplogroup L3 basal lineages migrated back to Africa from Asia around 70,000 years ago
  16. 336
    “…The Neanderthal genome paper presented a list of regions putatively targeted by positive selection around the time of the human–Neanderthal split. …”
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    On Characterizing Adaptive Events Unique to Modern Humans
  17. 337
    “…This population is either related to the Neanderthal-Denisova clade or diverged early from the Denisova lineage. …”
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    Approximate Bayesian computation with deep learning supports a third archaic introgression in Asia and Oceania
  18. 338
    “…These levels of Neanderthal admixture are consistent with an early divergence of Arab ancestors after the out-of-Africa bottleneck but before the major Neanderthal admixture events in Europe and other regions of Eurasia. …”
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    Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations
  19. 339
    “…We also find that the Neanderthal FADS haplotype is more closely related to the derived haplogroup and the Denisovan clusters closer to the ancestral haplogroup. …”
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    Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World
  20. 340
    por Petsko, Gregory A
    Publicado 2006
    “…The problem with reaching 'senior faculty' status is the feeling that you have nothing much to contribute except experience, but the recently announced Neanderthal Genome Project might put things into perspective.…”
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    Senior moments
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