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Mostrando 361 - 380 Resultados de 434 Para Buscar '"Neanderthals"', tiempo de consulta: 0.22s Limitar resultados
  1. 361
    “…By the late 1990s, published genetic work had largely concluded that archaic groups made no lasting genetic contribution to modern humans; less than a decade later, this conclusion was reversed following the successful DNA sequencing of an ancient Neanderthal. This reversal of consensus is noteworthy, but the reasoning behind it is not widely understood across all academic communities. …”
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    Inferring archaic introgression from hominin genetic data
  2. 362
    “…We report ubiquitous positive selection at nucleotide positions corresponding to DNA contact residues and the expansion of ZFs within clades, which confirms the rapid evolution of the ZF domain throughout the primate lineage. Alignment of Neanderthal and Denisovan sequences suggests that PRDM9 in archaic hominins was closely related to present-day human alleles that are rare and specific to African populations. …”
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    Primate evolution of the recombination regulator PRDM9
  3. 363
    “…Differences in ancestry composition, as the result of migration and admixture, have generated in Italy the largest degree of population structure detected so far in the continent, as well as shaping the amount of Neanderthal DNA in modern-day populations.…”
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    Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe
  4. 364
    “…The Neanderthal and Denisovan genomes enabled the discovery of sequences that differ between modern and archaic humans, the majority of which are noncoding. …”
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    The cis-regulatory effects of modern human-specific variants
  5. 365
    “…By applying the method to Neanderthal DNA extracts that are heavily contaminated with present-day human DNA, we show that the fraction of useful sequence information increases ∼10-fold and that the resulting sequences are more efficiently depleted of human contamination than when using purely computational approaches. …”
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    Selective enrichment of damaged DNA molecules for ancient genome sequencing
  6. 366
    “…These regions further correspond to chromosomal sections shown to be devoid of Neanderthal introgression into modern humans. This suggests that the same X-linked regions that undergo selective sweeps are among the first to form reproductive barriers between diverging species. …”
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    Strong Selective Sweeps on the X Chromosome in the Human-Chimpanzee Ancestor Explain Its Low Divergence
  7. 367
    “…Finally, we applied the method to a well-known Neanderthal cranium that exhibits signs of taphonomically induced asymmetry.…”
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    Retrodeformation of fossil specimens based on 3D bilateral semi-landmarks: Implementation in the R package “Morpho”
  8. 368
    “…Furthermore, we detect a longstanding increased plasticity of immune gene splicing, and show that positive selection and Neanderthal introgression have both contributed to diversify the splicing landscape of human populations. …”
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    Defining the genetic and evolutionary architecture of alternative splicing in response to infection
  9. 369
    “…To further add to the existing complexity, we also detect greater Denisovan than Neanderthal ancestry in ancient Uruguay and Panama individuals. …”
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    Genomic evidence for ancient human migration routes along South America's Atlantic coast
  10. 370
    “…The X chromosome in non-African humans shows less diversity and less Neanderthal introgression than expected from neutral evolution. …”
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    Extraordinary selection on the human X chromosome associated with archaic admixture
  11. 371
    por Chung, Seungwon, Son, Jung-Woo
    Publicado 2023
    “…Furthermore, the authors investigated the explanatory power of the paradoxical functional facilitation theory, the superior visual perception hypothesis, the “Hmmmmm” hypothesis, and the Neanderthal theory of autism regarding the emergence of autistic savant artists. …”
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    How Well Do We Understand Autistic Savant Artists: A Review of Various Hypotheses and Research Findings to Date
  12. 372
    “…Eight new alleles were identified in the Neanderthal and/or Denisova genetic pools. Four others, possibly affecting cognition, occured both in the sapiens and two other archaic genomes. …”
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    Homo sapiens, Homo neanderthalensis and the Denisova specimen: New insights on their evolutionary histories using whole-genome comparisons
  13. 373
    “…By testing the distribution of schizophrenia single nucleotide polymorphisms (SNPs) with risk and protective effects in the human-specific sites, we observed a negative selection of risk alleles for schizophrenia in modern humans relative to archaic humans (e.g., Neanderthal and Denisovans). Such findings indicate that risk alleles of schizophrenia have been gradually removed from the modern human genome due to negative selection pressure. …”
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    Interrogating the Evolutionary Paradox of Schizophrenia: A Novel Framework and Evidence Supporting Recent Negative Selection of Schizophrenia Risk Alleles
  14. 374
    “…We found no genetic traces of early expansions out-of-Africa in present-day populations but found Arabians have elevated Basal Eurasian ancestry that dilutes their Neanderthal ancestry. Population sizes within the region started diverging 15–20 kya, when Levantines expanded while Arabians maintained smaller populations that derived ancestry from local hunter-gatherers. …”
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    The genomic history of the Middle East
  15. 375
    “…Sima de los Huesos) currently assigned to H. heidelbergensis s.s. be reassigned to Homo neanderthalensis to reflect the early appearance of Neanderthal derived traits in the Middle Pleistocene in the region; and (3) that the Middle Pleistocene Asian fossils, particularly from China, likely represent a different lineage altogether.…”
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    Resolving the “muddle in the middle”: The case for Homo bodoensis sp. nov.
  16. 376
    por Sainudiin, Raazesh, York, Thomas
    Publicado 2009
    “…RESULTS: The posterior samples from the auto-validating sampler are used to rigorously (i) estimate posterior probabilities for different rooted topologies based on mitochondrial DNA from human, chimpanzee and gorilla, (ii) conduct a non-parametric test of rate variation between protein-coding and tRNA-coding sites from three primates and (iii) obtain a posterior estimate of the human-neanderthal divergence time. CONCLUSION: This solves the open problem of rigorously drawing independent and identically distributed samples from the posterior distribution over rooted and unrooted small tree spaces (3 or 4 taxa) based on any multiply-aligned sequence data.…”
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    Auto-validating von Neumann rejection sampling from small phylogenetic tree spaces
  17. 377
    “…The belated emergence of Levallois technology in Italy compared to western Europe corresponds to the late Italian Neanderthal speciation event. The new radiometric dates and the technological analyses of San Bernardino Cave raise the issue of the different roles of glacial refugia in the peopling and the spread of innovative flaking strategies in Europe during the late Middle Pleistocene.…”
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    San Bernardino Cave (Italy) and the Appearance of Levallois Technology in Europe: Results of a Radiometric and Technological Reassessment
  18. 378
    “…More recently, a study has identified a 50 kb genomic segment introgressed from Neanderthal adding a risk for COVID-19, and this genomic segment is present among 16% and 50% people of European and South Asian descent, respectively. …”
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    The major genetic risk factor for severe COVID-19 does not show any association among South Asian populations
  19. 379
    “…Similar to other hunter-gatherer populations of MSEA, we also find the Maniq to possess low levels of Neanderthal ancestry and undetectable levels of Denisovan ancestry. …”
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    Unveiling the Genetic History of the Maniq, a Primary Hunter-Gatherer Society
  20. 380
    por Ma, Xixian, Xu, Shuhua
    Publicado 2022
    “…Interestingly, the putative adaptive haplotype at SLC35F4 was of Neanderthal ancestry, while that at SLC35F3 was also likely of archaic origins. …”
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    Archaic introgression contributed to the pre-agriculture adaptation of vitamin B1 metabolism in East Asia
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