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381por Lazaridis, Iosif, Nadel, Dani, Rollefson, Gary, Merrett, Deborah C., Rohland, Nadin, Mallick, Swapan, Fernandes, Daniel, Novak, Mario, Gamarra, Beatriz, Sirak, Kendra, Connell, Sarah, Stewardson, Kristin, Harney, Eadaoin, Fu, Qiaomei, Gonzalez-Fortes, Gloria, Jones, Eppie R., Roodenberg, Songül Alpaslan, Lengyel, György, Bocquentin, Fanny, Gasparian, Boris, Monge, Janet M., Gregg, Michael, Eshed, Vered, Mizrahi, Ahuva-Sivan, Meiklejohn, Christopher, Gerritsen, Fokke, Bejenaru, Luminita, Blüher, Matthias, Campbell, Archie, Cavalleri, Gianpiero, Comas, David, Froguel, Philippe, Gilbert, Edmund, Kerr, Shona M., Kovacs, Peter, Krause, Johannes, McGettigan, Darren, Merrigan, Michael, Merriwether, D. Andrew, O'Reilly, Seamus, Richards, Martin B., Semino, Ornella, Shamoon-Pour, Michel, Stefanescu, Gheorghe, Stumvoll, Michael, Tönjes, Anke, Torroni, Antonio, Wilson, James F., Yengo, Loic, Hovhannisyan, Nelli A., Patterson, Nick, Pinhasi, Ron, Reich, David“…We show that the earliest populations of the Near East derived around half their ancestry from a ‘Basal Eurasian’ lineage that had little if any Neanderthal admixture and that separated from other non-African lineages prior to their separation from each other. …”
Publicado 2016
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382por Delgobo, Murilo, Mendes, Daniel AGB, Kozlova, Edgar, Rocha, Edroaldo Lummertz, Rodrigues-Luiz, Gabriela F, Mascarin, Lucas, Dias, Greicy, Patrício, Daniel O, Dierckx, Tim, Bicca, Maíra A, Bretton, Gaëlle, Tenório de Menezes, Yonne Karoline, Starick, Márick R, Rovaris, Darcita, Del Moral, Joanita, Mansur, Daniel S, Van Weyenbergh, Johan, Báfica, André“…Furthermore, genetic and functional analysis revealed the IL6/IL6R/CEBP gene module has undergone recent evolutionary selection, including Neanderthal introgression and human pathogen adaptation, connected to systemic monocyte counts. …”
Publicado 2019
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383por Yuan, Kai, Ni, Xumin, Liu, Chang, Pan, Yuwen, Deng, Lian, Zhang, Rui, Gao, Yang, Ge, Xueling, Liu, Jiaojiao, Ma, Xixian, Lou, Haiyi, Wu, Taoyang, Xu, Shuhua“…The new method enabled us to discern two waves of introgression from both Denisovan-like and Neanderthal-like hominins in present-day Eurasian populations and an ancient Siberian individual. …”
Publicado 2021
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384“…The time period between 560 and 360 ka (MIS14 to MIS11) was critical for the evolution of the Neanderthal lineage and the appearance of Levallois technology in Europe. …”
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385“…The study of the lithic assemblages of two French sites, the Bau de l’Aubesier and Payre, contributes new knowledge of the earliest Neanderthal techno-cultural variability. In this paper we present the results of a detailed technological analysis of Early Middle Palaeolithic lithic assemblages of MIS 8 and 7 age from the two sites, which are located on opposite sides of the Rhône Valley in the south-east of France. …”
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386por Savriama, Yoland, Valtonen, Mia, Kammonen, Juhana I., Rastas, Pasi, Smolander, Olli-Pekka, Lyyski, Annina, Häkkinen, Teemu J., Corfe, Ian J., Gerber, Sylvain, Salazar-Ciudad, Isaac, Paulin, Lars, Holm, Liisa, Löytynoja, Ari, Auvinen, Petri, Jernvall, Jukka“…We show that the genetic distance between these species is more than twice the modern human–Neanderthal distance, but still within that of morphologically similar species pairs known to hybridize. …”
Publicado 2018
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387por Mughal, Mehreen R., Koch, Hillary, Huang, Jinguo, Chiaromonte, Francesca, DeGiorgio, Michael“…In addition, we identify BNC2 in Europeans as a target of adaptive introgression, and predict that it harbors a beneficial mutation that arose in an archaic human population that split from modern humans within the hypothesized modern human-Neanderthal divergence range.…”
Publicado 2020
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388por Natri, Heini M., Hudjashov, Georgi, Jacobs, Guy, Kusuma, Pradiptajati, Saag, Lauri, Darusallam, Chelzie Crenna, Metspalu, Mait, Sudoyo, Herawati, Cox, Murray P., Gallego Romero, Irene, Banovich, Nicholas E.“…By combining local ancestry and archaic introgression inference with eQTLs and methylQTLs, we identify regulatory loci driven by modern Papuan ancestry as well as introgressed Denisovan and Neanderthal variation. GWAS colocalization connects QTLs detected here to hematological traits, and further comparison with European datasets reflects the poor overall transferability of GWAS statistics across diverse populations. …”
Publicado 2022
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389por Bañuls-Cardona, Sandra, Blasco, Ruth, Rosell, Jordi, Rufà, Anna, Vallverdú, Josep, Rivals, Florent“…Furthermore, the results provide us with relevant information on the types of accumulations of remains in the caves (short vs. long term), as well as on the seasonality of Neanderthal occupations during the Upper Pleistocene (MIS5-3) of the northeastern Iberian Peninsula.…”
Publicado 2022
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390“…Modern people with high frequencies of Neanderthal genes, have notable anatomical features such as increased skull width in the occipital and parietal visual areas. …”
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391por Austin, Christine, Smith, Tanya M., Bradman, Asa, Hinde, Katie, Joannes-Boyau, Renaud, Bishop, David, Hare, Dominic J., Doble, Philip, Eskenazi, Brenda, Arora, Manish“…We also document transitions in a Middle Palaeolithic juvenile Neanderthal, which shows a pattern of exclusive breastfeeding for seven months, followed by seven months of supplementation. …”
Publicado 2013
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392por Monge, Guadalupe, Jimenez-Espejo, Francisco J., García-Alix, Antonio, Martínez-Ruiz, Francisca, Mattielli, Nadine, Finlayson, Clive, Ohkouchi, Naohiko, Sánchez, Miguel Cortés, de Castro, Jose María Bermúdez, Blasco, Ruth, Rosell, Jordi, Carrión, José, Rodríguez-Vidal, Joaquín, Finlayson, Geraldine“…The earliest anthropogenic pollution evidence is related to Neanderthal hearths from Gorham's Cave (Gibraltar), being one of the first milestones in the so-called “Anthropocene”. …”
Publicado 2015
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393“…Finally, tephra fallout impacts would have interrupted the westward migration of modern hominid groups in Europe, possibly supporting the hypothesis of prolonged Neanderthal survival in South-Western Europe during the Middle to Upper Palaeolithic transition.…”
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394por Yee, Sook Wah, Ferrández-Peral, Luis, Alentorn, Pol, Fontsere, Claudia, Ceylan, Merve, Koleske, Megan L., Handin, Niklas, Artegoitia, Virginia M., Lara, Giovanni, Chien, Huan-Chieh, Zhou, Xujia, Dainat, Jacques, Zalevsky, Arthur, Sali, Andrej, Brand, Colin M., Capra, John A., Artursson, Per, Newman, John W., Marques-Bonet, Tomas, Giacomini, Kathleen M.“…Site-directed mutagenesis yielding the human SLC22A10-P220L produced a protein with excellent plasma membrane localization and associated uptake function. Neanderthal and Denisovan genomes show human-like sequences at proline 220 position, corroborating that SLC22A10 were rendered nonfunctional during hominin evolution after the divergence from the pan lineage (chimpanzees and bonobos). …”
Publicado 2023
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395por Yee, Sook Wah, Ferrández-Peral, Luis, Alentorn, Pol, Fontsere, Claudia, Ceylan, Merve, Koleske, Megan L., Handin, Niklas, Artegoitia, Virginia M., Lara, Giovanni, Chien, Huan-Chieh, Zhou, Xujia, Dainat, Jacques, Zalevsky, Arthur, Sali, Andrej, Brand, Colin M., Capra, John A., Artursson, Per, Newman, John W., Marques-Bonet, Tomas, Giacomini, Kathleen M.“…Site-directed mutagenesis yielding the human SLC22A10-P220L produced a protein with excellent plasma membrane localization and associated uptake function. Neanderthal and Denisovan genomes show human-like sequences at proline 220 position, corroborating that SLC22A10 were rendered nonfunctional during hominin evolution after the divergence from the pan lineage (chimpanzees and bonobos). …”
Publicado 2023
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396por Webb, Andrew E., Gerek, Z. Nevin, Morgan, Claire C., Walsh, Thomas A., Loscher, Christine E., Edwards, Scott V., O’Connell, Mary J.“…Then we used population genomic data from the recently completed Neanderthal genome project, the 1000 human genomes project, and the 17 laboratory mouse genomes project to determine whether the residues that were putatively positively selected are fixed or variable in these populations. …”
Publicado 2015
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397“…The most explanatory scenario suggests that ancestral HPV16 already infected ancestral human populations and that viral lineages co-diverged with the hosts in parallel with the split between archaic Neanderthal-Denisovans and ancestral modern human populations, generating the ancestral HPV16A and HPV16BCD viral lineages, respectively. …”
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398por Rodríguez, Willy, Mazet, Olivier, Grusea, Simona, Arredondo, Armando, Corujo, Josué M., Boitard, Simon, Chikhi, Lounès“…As an example we address the question of human and Neanderthal evolution and discuss how the NSSC framework allows to interpret genomic data under this new perspective.…”
Publicado 2018
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399por Mohammed Ismail, Wazim, Pagel, Kymberleigh A., Pejaver, Vikas, Zhang, Simo V., Casasa, Sofia, Mort, Matthew, Cooper, David N., Hahn, Matthew W., Radivojac, Predrag“…Our analysis confirmed gene flow between Neanderthal and ancestral pan-European populations, with similar contributions to the Serbian genome as those observed in other European groups. …”
Publicado 2018
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400por Rüther, Patrick Leopold, Husic, Immanuel Mirnes, Bangsgaard, Pernille, Gregersen, Kristian Murphy, Pantmann, Pernille, Carvalho, Milena, Godinho, Ricardo Miguel, Friedl, Lukas, Cascalheira, João, Taurozzi, Alberto John, Jørkov, Marie Louise Schjellerup, Benedetti, Michael M., Haws, Jonathan, Bicho, Nuno, Welker, Frido, Cappellini, Enrico, Olsen, Jesper Velgaard“…Finally, we demonstrate the high throughput capabilities of the method in a high-degradation context by analyzing more than two hundred Middle and Upper Palaeolithic bones from Southern European sites with late Neanderthal occupation. While this initial study is focused on modern and archaeological mammalian bone, SPIN will be open and expandable to other biological tissues and taxa.…”
Publicado 2022
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