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Mostrando 421 - 434 Resultados de 434 Para Buscar '"Neanderthals"', tiempo de consulta: 0.12s Limitar resultados
  1. 421
    por Delpiano, Davide, Uthmeier, Thorsten
    Publicado 2020
    “…A higher regional mobility caused by the comparably low predictability of resources characterized the subsistence tactics of Neanderthal groups especially at the borders of their overall distribution. …”
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    Techno-functional and 3D shape analysis applied for investigating the variability of backed tools in the Late Middle Paleolithic of Central Europe
  2. 422
    “…Furthermore, mdig may coordinate with the Neanderthal variants linked to an elevated mortality of COVID-19. …”
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    Environmentally-induced mdig contributes to the severity of COVID-19 through fostering expression of SARS-CoV-2 receptor NRPs and glycan metabolism
  3. 423
    “…Finally, applying the CN1 as a reference, we discovered 5.80 Mb and 4.21 Mb putative introgression sequences from Neanderthal and Denisovan, respectively, including many East Asian specific ones undetected using CHM13 as the reference. …”
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    The complete and fully-phased diploid genome of a male Han Chinese
  4. 424
    “…Moreover, with the use of the high-quality de novo assembly, we observed a much higher rate of genome-wide archaic hominid (Altai Neanderthal and Denisovan) shared non-reference sequences in ZF1 (1.32%–1.53%) compared to other East Asian genomes (0.70%–0.98%), reflecting a unique genomic composition of Tibetans. …”
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    De novo assembly of a Tibetan genome and identification of novel structural variants associated with high-altitude adaptation
  5. 425
    por Eising, Else, Mirza-Schreiber, Nazanin, de Zeeuw, Eveline L., Wang, Carol A., Truong, Dongnhu T., Allegrini, Andrea G., Shapland, Chin Yang, Zhu, Gu, Wigg, Karen G., Gerritse, Margot L., Molz, Barbara, Alagöz, Gökberk, Gialluisi, Alessandro, Abbondanza, Filippo, Rimfeld, Kaili, van Donkelaar, Marjolein, Liao, Zhijie, Jansen, Philip R., Andlauer, Till F. M., Bates, Timothy C., Bernard, Manon, Blokland, Kirsten, Bonte, Milene, Børglum, Anders D., Bourgeron, Thomas, Brandeis, Daniel, Ceroni, Fabiola, Csépe, Valéria, Dale, Philip S., de Jong, Peter F., DeFries, John C., Démonet, Jean-François, Demontis, Ditte, Feng, Yu, Gordon, Scott D., Guger, Sharon L., Hayiou-Thomas, Marianna E., Hernández-Cabrera, Juan A., Hottenga, Jouke-Jan, Hulme, Charles, Kere, Juha, Kerr, Elizabeth N., Koomar, Tanner, Landerl, Karin, Leonard, Gabriel T., Lovett, Maureen W., Lyytinen, Heikki, Martin, Nicholas G., Martinelli, Angela, Maurer, Urs, Michaelson, Jacob J., Moll, Kristina, Monaco, Anthony P., Morgan, Angela T., Nöthen, Markus M., Pausova, Zdenka, Pennell, Craig E., Pennington, Bruce F., Price, Kaitlyn M., Rajagopal, Veera M., Ramus, Franck, Richer, Louis, Simpson, Nuala H., Smith, Shelley D., Snowling, Margaret J., Stein, John, Strug, Lisa J., Talcott, Joel B., Tiemeier, Henning, van der Schroeff, Marc P., Verhoef, Ellen, Watkins, Kate E., Wilkinson, Margaret, Wright, Margaret J., Barr, Cathy L., Boomsma, Dorret I., Carreiras, Manuel, Franken, Marie-Christine J., Gruen, Jeffrey R., Luciano, Michelle, Müller-Myhsok, Bertram, Newbury, Dianne F., Olson, Richard K., Paracchini, Silvia, Paus, Tomáš, Plomin, Robert, Reilly, Sheena, Schulte-Körne, Gerd, Tomblin, J. Bruce, van Bergen, Elsje, Whitehouse, Andrew J. O., Willcutt, Erik G., St Pourcain, Beate, Francks, Clyde, Fisher, Simon E.
    Publicado 2022
    “…Heritability was enriched for genomic elements regulating gene expression in the fetal brain and in chromosomal regions that are depleted of Neanderthal variants. Together, these results provide avenues for deciphering the biological underpinnings of uniquely human traits.…”
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    Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people
  6. 426
    “…OBJECTIVES: Intra‐tooth patterns of trace elements barium (Ba) and strontium (Sr) have been used to infer human and nonhuman primate nursing histories, including australopithecine and Neanderthal juveniles. Here, we contrast the two elemental models in first molars (M1s) of four wild baboons and explore the assumptions that underlie each. …”
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    Elemental models of primate nursing and weaning revisited
  7. 427
    “…By interrogating allele frequencies in more than 100 diverse human populations and resequencing Neanderthal DNA, we confirmed the ancestral state of this locus and found a strong geographical gradient for the derived allele (Val372), with near fixation in West Africa. …”
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    Extreme Population Differences in the Human Zinc Transporter ZIP4 (SLC39A4) Are Explained by Positive Selection in Sub-Saharan Africa
  8. 428
    “…Here, we present the modification and optimization of a PEC method, earlier developed for sequencing the Neanderthal mitochondrial genome, with forensic applications in mind. …”
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    Optimized mtDNA Control Region Primer Extension Capture Analysis for Forensically Relevant Samples and Highly Compromised mtDNA of Different Age and Origin
  9. 429
    “…The exit took place 50,300–81,000 years ago (latest date for FT lineage expansion outside Africa – earliest date for the D/D0 lineage split inside Africa), and most likely 50,300–59,400 years ago (considering Neanderthal admixture). This work resolves a long-running debate about Y-chromosomal out-of-Africa/back-to-Africa migrations, and provides insights into the out-of-Africa expansion more generally.…”
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    A Rare Deep-Rooting D0 African Y-Chromosomal Haplogroup and Its Implications for the Expansion of Modern Humans Out of Africa
  10. 430
    “…The GenoChip includes ancestry informative markers obtained for over 450 human populations, an ancient human (Saqqaq), and two archaic hominins (Neanderthal and Denisovan) and was designed to identify all known Y-chromosome and mtDNA haplogroups. …”
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    The GenoChip: A New Tool for Genetic Anthropology
  11. 431
    “…Additionally, longitudinal transcriptome analyses revealed a more persistent retention of immune signatures in Alpha+E484K patients throughout the entire course of COVID-19 disease and convalescence. While the OAS1 Neanderthal mutation has been linked to a milder COVID-19 pathology, we did not identify significant immune transcriptomes differences in the 25 patients homozygous for this mutation. …”
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    Immune transcriptome analysis of COVID-19 patients infected with SARS-CoV-2 variants carrying the E484K escape mutation identifies a distinct gene module
  12. 432
    “…We then use AD-LIBS to infer ancestry in two published data sets: European human genomes with Neanderthal ancestry and brown bear genomes with polar bear ancestry. …”
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    AD-LIBS: inferring ancestry across hybrid genomes using low-coverage sequence data
  13. 433
    “…BLAST analyses of ancient human genome sequences uncovered several homozygous carriers of variant P2X7 alleles, possibly reflecting a high degree of inbreeding, e.g., H—R—T for a 50.000 year old Neanderthal, H—R—A for a 24.000 year old Siberian, and Y—R—A for a 7,000 year old mesolithic European. …”
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    Origin, distribution, and function of three frequent coding polymorphisms in the gene for the human P2X7 ion channel
  14. 434
    “…Finally, we showed that SARS-CoV-2 infection in the Sardinian population is also influenced by other genetic factors such as β-thalassemia trait (rs11549407C>T in the HBB gene), KIR2DS2/HLA-C C1+ group combination and the HLA-B*58:01, C*07:01, DRB1*03:01 haplotype which exert a protective effect [P = 0.005, P = 0.001 and P = 0.026 respectively]. Conversely, the Neanderthal LZTFL1 gene variant (rs35044562A>G) shows a detrimental consequence on the disease course [P = 0.001]. …”
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    A review of the main genetic factors influencing the course of COVID-19 in Sardinia: the role of human leukocyte antigen-G
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